Screening Gene Mutations in Myeloid Cancers by Next Generation Sequencing to Improve Treatment Results
NCT04060485 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2019-08-19
Summary
Genetic mutations have closely linked to the pathogenesis and prognostication of myeloid cancers. In addition, a number of molecularly targeted agents have been developed in recent years. With the advent of next generation sequencing (NGS), we now are able to detect a wide range of mutations more rapidly, accurately, and economically. In this study, the investigators will use NGS to screen and analyze myeloid-associated gene mutations in the participants, and aim to build up the mutational landscapes of the various myeloid cancers, and investigate how these mutations are linked to clinical outcome.
Conditions
- Acute Myeloid Leukemia
- Myelodysplastic Syndromes
- Myeloproliferative Neoplasm
- Aplastic Anemia
Sponsors & Collaborators
-
National Taiwan University Hospital
lead OTHER
Principal Investigators
-
Wen-Chien Chou, MD, PhD · National Taiwan University Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 120 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-08-19
- Primary Completion
- 2024-08-31
- Completion
- 2024-12-31
Countries
- Taiwan
Study Locations
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