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Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer

NCT00755313 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 81

Last updated 2017-11-24

No results posted yet for this study

Summary

RATIONALE: Gathering information over time from laboratory tests, imaging scans, and assessment tests may help doctors learn more about the side effects of chemotherapy and plan the best treatment.

PURPOSE: This clinical trial is studying the effects of chemotherapy on the brain in women with newly diagnosed early-stage breast cancer.

Conditions

  • Breast Cancer
  • Chemotherapeutic Agent Toxicity
  • Cognitive/Functional Effects
  • Fatigue
  • Long-term Effects Secondary to Cancer Therapy in Adults
  • Neurotoxicity
  • Psychosocial Effects of Cancer and Its Treatment

Interventions

BIOLOGICAL

trastuzumab

DRUG

aromatase inhibition therapy

DRUG

carboplatin

DRUG

cyclophosphamide

DRUG

docetaxel

DRUG

doxorubicin hydrochloride

OTHER

metabolic assessment

OTHER

questionnaire administration

OTHER

study of socioeconomic and demographic variables

PROCEDURE

cognitive assessment

PROCEDURE

positron emission tomography

RADIATION

fludeoxyglucose F 18

Sponsors & Collaborators

Principal Investigators

  • Hope S. Rugo, MD · University of California, San Francisco

Eligibility

Min Age
35 Years
Max Age
80 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-05-31
Primary Completion
2012-09-30
Completion
2014-06-06

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00755313 on ClinicalTrials.gov