Chemotherapy in Treating Women With Previously Treated Metastatic Breast Cancer
NCT00003236 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2023-06-18
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: Randomized phase II trial to compare the effectiveness of ISIS 5132 with ISIS 3521 in treating women who have metastatic breast cancer that has not responded to previous therapy.
Conditions
Interventions
- BIOLOGICAL
-
ISIS 3521
- DRUG
-
ISIS 5132
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Eastern Cooperative Oncology Group
lead NETWORK
Principal Investigators
-
William J. Gradishar, MD · Robert H. Lurie Cancer Center
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Max Age
- 120 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-07-13
- Primary Completion
- 2002-06-30
Countries
- United States
Study Locations
More Related Trials
-
A Study to Determine the Antitumor Activity and Evaluate the Safety of MKC-1
NCT00306631 ·Status: COMPLETED ·Phase: PHASE2
-
PS-341 in Treating Women With Metastatic Breast Cancer
NCT00028639 ·Status: COMPLETED ·Phase: PHASE2
-
ICI 182780 in Treating Women With Metastatic Breast Cancer
NCT00012025 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Chemotherapy Alone in Treating Women With Stage IV Breast Cancer
NCT00012311 ·Status: UNKNOWN ·Phase: PHASE2
-
Chemotherapy Followed by Surgery in Treating Women With Stage II or Stage III Breast Cancer
NCT00003953 ·Status: COMPLETED ·Phase: PHASE2
-
Pegylated Liposomal Doxorubicin Hydrochloride and Carboplatin Followed by Surgery and Paclitaxel in Treating Patients With Triple Negative Stage II-III Breast Cancer
NCT02315196 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Fulvestrant and Bevacizumab in Treating Patients With Metastatic Breast Cancer
NCT00423917 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy in Treating Women With Metastatic Breast Cancer
NCT00004046 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy and Peripheral Stem Cell Transplantation Followed by Trastuzumab in Treating Women With Metastatic Breast Cancer
NCT00006123 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Carboplatin or Docetaxel in Treating Women With Metastatic Genetic Breast Cancer
NCT00321633 ·Status: COMPLETED ·Phase: PHASE2
-
Open Label Trial of INCB07839 to Determine Effect and Safety of INCB007839 Plus Trastuzumab in HER2 Positive Metastatic Breast Cancer
NCT00864175 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Docetaxel Combined With Estramustine in Treating Women With Metastatic Breast Cancer
NCT00003066 ·Status: UNKNOWN ·Phase: PHASE2
-
Irinotecan and Docetaxel in Treating Patients With Refractory Metastatic Breast Cancer
NCT00079118 ·Status: COMPLETED ·Phase: PHASE2
-
Molecular Profile of Breast Cancer in Ugandan Patients With Stage IIB-III Breast Cancer
NCT03518242 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BTX-9341 in Advanced and/or Metastatic Breast Cancer
NCT06515470 ·Status: RECRUITING ·Phase: PHASE1
-
Trial of BDC-1001 +/- Pertuzumab in Subjects With HER2-Positive Metastatic Breast Cancer
NCT05954143 ·Status: TERMINATED ·Phase: PHASE2
-
A Pre-Surgical PK Study of IM and Intraductally Delivered Fulvestrant
NCT02540330 ·Status: TERMINATED ·Phase: PHASE2
-
Combination Chemotherapy Following Surgery in Treating Women With Early Stage Breast Cancer
NCT00003012 ·Status: COMPLETED ·Phase: PHASE3
-
Assessing the Efficacy of Paclitaxel and Olaparib in Comparison to Paclitaxel / Carboplatin Followed by Epirubicin/Cyclophosphamide as Neoadjuvant Chemotherapy in Patients With HER2-negative Early Breast Cancer and Homologous Recombination Deficiency
NCT02789332 ·Status: COMPLETED ·Phase: PHASE2
-
Doxorubicin or Epirubicin and Cyclophosphamide in Treating Older Women With Invasive Breast Cancer
NCT00516425 ·Status: UNKNOWN ·Phase: PHASE3
-
Combination Chemotherapy With or Without Colony-stimulating Factors in Treating Women With Breast Cancer
NCT00014222 ·Status: COMPLETED ·Phase: PHASE3
-
Sulindac and Docetaxel in Treating Women With Metastatic or Recurrent Breast Cancer
NCT00039520 ·Status: COMPLETED ·Phase: PHASE2
-
Gedatolisib Plus Talazoparib in Advanced Triple Negative or BRCA1/2 Positive, HER2 Negative Breast Cancers
NCT03911973 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Phase II Study of AZD2281 in Patients With Known BRCA Mutation Status or Recurrent High Grade Ovarian Cancer or Patients With Known BRCA Mutation Status/ Triple Neg Breast Cancer
NCT00679783 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluating Efficacy and Tolerability of Anticancer Drug Therapies for the Treatment of Gynecologic and Breast Cancers
NCT06800612 ·Status: RECRUITING