Studying Tissue Samples From Women Who Underwent Chemotherapy for Lymph Node-Positive Stage II or Stage IIIA Breast Cancer on Clinical Trial CLB-9741 or CLB-9344
NCT00897026 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1195
Last updated 2021-08-17
Summary
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors plan the best treatment.
PURPOSE: This research study is looking at tissue samples from women who underwent chemotherapy for lymph node-positive stage II or stage IIIA breast cancer.
Conditions
Interventions
- DRUG
- DRUG
-
doxorubicin hydrochloride
- DRUG
- GENETIC
-
fluorescence in situ hybridization
- OTHER
-
immunohistochemistry staining method
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Alliance for Clinical Trials in Oncology
lead OTHER
Principal Investigators
-
Matthew Ellis, MD, PhD, FRCP · Washington University Siteman Cancer Center
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-07-31
- Primary Completion
- 2012-04-27
- Completion
- 2012-04-27
Countries
- United States
Study Locations
More Related Trials
-
Combination Chemotherapy With or Without Colony-stimulating Factors in Treating Women With Breast Cancer
NCT00014222 ·Status: COMPLETED ·Phase: PHASE3
-
S9719 Gene Damage Following Chemotherapy in Women With Stage II or Stage III Breast Cancer
NCT00003095 ·Status: COMPLETED
-
Study of Neoadjuvant Chemotherapy of Breast Cancer
NCT00830544 ·Status: UNKNOWN ·Phase: PHASE2
-
Combination Chemotherapy in Treating Women With Stage II or Stage IIIA Breast Cancer That Has Spread to the Lymph Nodes
NCT00004125 ·Status: COMPLETED ·Phase: PHASE3
-
Biological and Clinical Effects of Palbociclib With Ovarian Suppression and Letrozole in the Neoadjuvant Treatment of Breast Cancer
NCT03628066 ·Status: COMPLETED ·Phase: PHASE2
-
Biomarkers in Women Receiving Chemotherapy & Celecoxib for Stage II or Stage III Breast Cancer Removable by Surgery
NCT00665457 ·Status: TERMINATED ·Phase: PHASE2
-
A Study To Assess The Tolerability And Clinical Activity Of Gedatolisib In Combination With Palbociclib/Letrozole Or Palbociclib/Fulvestrant In Women With Metastatic Breast Cancer
NCT02684032 ·Status: COMPLETED ·Phase: PHASE1
-
AZD2171 and Combination Chemotherapy in Treating Women With Locally Advanced Breast Cancer
NCT00310089 ·Status: COMPLETED ·Phase: NA
-
Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer
NCT05020860 ·Status: RECRUITING ·Phase: PHASE2
-
Docetaxel and Cyclophosphamide Compared to Anthracycline-Based Chemotherapy in Treating Women With HER2-Negative Breast Cancer
NCT01547741 ·Status: UNKNOWN ·Phase: PHASE3
-
Palbociclib and Letrozole or Fulvestrant in Treating Patients With Estrogen Receptor Positive, HER2 Negative Metastatic Breast Cancer
NCT03633331 ·Status: COMPLETED ·Phase: PHASE2
-
Assessing the Efficacy of Paclitaxel and Olaparib in Comparison to Paclitaxel / Carboplatin Followed by Epirubicin/Cyclophosphamide as Neoadjuvant Chemotherapy in Patients With HER2-negative Early Breast Cancer and Homologous Recombination Deficiency
NCT02789332 ·Status: COMPLETED ·Phase: PHASE2
-
Real Time Molecular Analysis of Breast Cancer Receiving Neo-adjuvant Chemotherapy
NCT04504747 ·Status: RECRUITING
-
Selective Neoadjuvant Treatment According to Immunohistochemical Subtype for HER2 Negative Breast Cancer Patients
NCT00432172 ·Status: COMPLETED ·Phase: PHASE2
-
Impact of Endocrine Therapy and Abemaciclib on Host and Tumor Immune Cell Repertoire/Function in Advanced ER+/HER2- Breast Cancer
NCT04352777 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant Chemotherapy + Herceptin in HER2 Positive Stage II-III Breast Cancer Patients
NCT00270894 ·Status: COMPLETED ·Phase: PHASE2
-
Phase III Study of Gemcitabine Plus a Cytotoxic Agent Versus Two Cytotoxic Agents
NCT00191438 ·Status: COMPLETED ·Phase: PHASE3
-
Primary Chemotherapy With Docetaxel-Capecitabine and Doxorubicin-Cyclophosphamide in Breast Cancer
NCT00005908 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy Before Surgery and Tissue Sample Collection in Patients With Stage IIA-IIIC Breast Cancer
NCT01897441 ·Status: TERMINATED ·Phase: NA
-
Carboplatin+Nab-paclitaxel, Plus Trastuzumab (HER2+) or Bevacizumab (HER2-) in the Neoadjuvant Setting
NCT00618657 ·Status: COMPLETED ·Phase: PHASE2
-
Phase III Comparison of Adjuvant Chemotherapy W/High-Dose Cyclophosphamide Plus Doxorubicin (AC) vs Sequential Doxorubicin Fol by Cyclophosphamide (A-C) in High Risk Breast Cancer Patients With 0-3 Positive Nodes (Intergroup, CALGB 9394)
NCT00590785 ·Status: COMPLETED ·Phase: PHASE3
-
Adjuvant Stage 2-3A Breast Cancer With Positive Lymph Nodes
NCT00007904 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Neoadjuvant Chemotherapy Plus Trastuzumab and Pertuzumab in HER2-Negative Breast Cancer Patients With Abnormal HER2 Signaling
NCT03412643 ·Status: UNKNOWN ·Phase: PHASE2
-
Genomic & Proteomic Analysis of Docetaxel & Capecitabine as Primary Chemo for Stage II-III Breast Cancer
NCT00198237 ·Status: COMPLETED ·Phase: PHASE2
-
TIL Relation to pCR After Neoadjuvant Therapy in Breast Cancer Patients
NCT05206396 ·Status: UNKNOWN