Docetaxel

Drug

Drug Profile

Docetaxel is a taxane chemotherapy medicine used for multiple cancers including breast, head and neck, stomach, prostate, and non-small-cell lung cancer. It is administered by slow IV infusion and may be used alone or in combination regimens. It is a prescription-only antineoplastic drug.

Drug Class
Taxane chemotherapy
Approval Status
Approved for medical use in 1995; prescription-only in major markets
Mechanism of Action
Disrupts normal microtubule function and thereby blocks cell division
Brand Names
  • Taxotere
  • Docecad
  • Docefrez
Indications
  • \Breast cancer\
  • \Head and neck cancer\
  • \Stomach cancer\
  • \Prostate cancer\
  • \Non-small-cell lung cancer\

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Related Clinical Trials

NCT ID Title Status Phase
NCT07609251

A Clinical Study of SCTB41 Combined With Docetaxel in Patients With Previously Treated Locally Advanced or Metastatic Non-Small Cell Lung Cancer(Phase II Study Ongoing)

NOT_YET_RECRUITING PHASE2
NCT07590934

Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer

NOT_YET_RECRUITING PHASE1/PHASE2
NCT07566052

A Study to Compare Setidegrasib (ASP3082) With Docetaxel, in People With Non-small Cell Lung Cancer With a KRAS G12D Mutation

NOT_YET_RECRUITING PHASE3
NCT07545044

A Study of JSKN003 Versus Trastuzumab in Combination With Pertuzumab and Docetaxel as First-Line Treatment for HER2-Positive Recurrent or Metastatic Breast Cancer

NOT_YET_RECRUITING PHASE2
NCT07528274

Microwave Ablation Plus Tislelizumab and Docetaxel in Advanced NSCLC After First-Line Immunotherapy Failure

RECRUITING PHASE2
NCT07518173

A Study of BL-M07D1 Combined With Pertuzumab Versus Docetaxel Plus Trastuzumab and Pertuzumab in Patients With First-line HER2-positive Recurrent or Metastatic Breast Cancer

NOT_YET_RECRUITING PHASE3
NCT07518147

A Study Comparing BL-M05D1 With the Investigator's Choice of Treatment Regimen in Patients With Claudin (CLDN)18.2-Positive Advanced Gastric Cancer or Gastroesophageal Junction Adenocarcinoma (GC/GEJC) Who Have Received Prior First-Line Treatment

NOT_YET_RECRUITING PHASE3
NCT07487896

A Study of YL201 Versus Investigator's Choice of Chemotherapy in Participants With Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma After Failure of First-Line Therapy

NOT_YET_RECRUITING PHASE3
NCT07464327

A Phase III Study of HS-20093 Injection Combined With Adebrelimab Versus Docetaxel in Previously Treated Patients With Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer Without Actionable Genomic Alterations

NOT_YET_RECRUITING PHASE3
NCT07459751

A Global Phase II/III Clinical Study to Evaluate the Efficacy and Safety of HLX43 Monotherapy or HLX43 in Combination With HLX07 Versus Docetaxel in Advanced or Metastatic Squamous Non-Small Cell Lung Cancer

RECRUITING PHASE2/PHASE3