Docetaxel

Drug

Drug Profile

Docetaxel is a taxane chemotherapy medicine used for multiple cancers including breast, head and neck, stomach, prostate, and non-small-cell lung cancer. It is administered by slow IV infusion and may be used alone or in combination regimens. It is a prescription-only antineoplastic drug.

Drug Class
Taxane chemotherapy
Approval Status
Approved for medical use in 1995; prescription-only in major markets
Mechanism of Action
Disrupts normal microtubule function and thereby blocks cell division
Brand Names
  • Taxotere
  • Docecad
  • Docefrez
Indications
  • \Breast cancer\
  • \Head and neck cancer\
  • \Stomach cancer\
  • \Prostate cancer\
  • \Non-small-cell lung cancer\

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Related Clinical Trials

NCT ID Title Status Phase
NCT07776639

Iparomlimab and Tuvonralimab Injection (QL1706) Combined With DOS as Neoadjuvant Therapy for Locally Advanced Adenocarcinoma of the Stomach and Gastroesophageal Junction

RECRUITING PHASE2
NCT07768189

A Study to Evaluate CRB-701 Compared to Investigator's Choice Therapy in Previously Treated Oropharyngeal Squamous Cell Carcinoma

NOT_YET_RECRUITING PHASE3
NCT07747740

Sequential Gemcitabine Plus Docetaxel Versus Gemcitabine Plus Mitomycin C for BCG-Unresponsive Non-Muscle-Invasive Bladder Cancer

RECRUITING PHASE2
NCT07743632

Neoadjuvant Angiogenesis-Targeting Bispecific Chemoimmunotherapy for TNBC

NOT_YET_RECRUITING PHASE2
NCT07730151

Efficacy and Safety of Darolutamide Combined With Docetaxel and ADT as Neoadjuvant Therapy for Locally Advanced Prostate Cancer.

NOT_YET_RECRUITING PHASE2
NCT07723248

A Study to Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Patients With mCRPC Who Were Previously Treated With Abiraterone Acetate (Himalayas-1)

RECRUITING PHASE3
NCT07699757

HSK41959 With Standard Therapy in Solid Tumors With MTAP Deletion

NOT_YET_RECRUITING PHASE1
NCT07698535

Measuring Circulating Tumor Deoxyribonucleic Acid Tumor Fraction to Guide Early 177Lu-PSMA-617 Treatment Discontinuation in Patients With Metastatic Castration-Resistant Prostate Cancer, DYNAMO Trial

NOT_YET_RECRUITING PHASE2
NCT07668752

A Study to Evaluate GFH375 Versus Docetaxel in Participants With Non-Small Cell Lung Cancer With KRAS G12D Mutation

RECRUITING PHASE3
NCT07662018

Prospective Observational Study of Outcomes After Gemcitabine, Docetaxel, Melphalan, and Carboplatin With Autologous Stem Cell Transplantation in Pediatric Relapsed/Refractory Germ Cell Tumors

RECRUITING