Observing Young Patients With Ependymoma Undergoing Standard Combination Chemotherapy
NCT00683319 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 50
Last updated 2013-09-20
Summary
RATIONALE: Gathering information about how young patients with ependymoma respond to standard combination chemotherapy and learning about the long-term effects of this treatment may help doctors plan better treatment.
PURPOSE: This phase III trial is observing young patients with ependymoma undergoing standard combination chemotherapy.
Conditions
- Brain and Central Nervous System Tumors
- Cognitive/Functional Effects
- Long-term Effects Secondary to Cancer Therapy in Children
- Ototoxicity
Interventions
- DRUG
- DRUG
- DRUG
- DRUG
-
methotrexate
- DRUG
-
vincristine sulfate
- PROCEDURE
-
adjuvant therapy
- PROCEDURE
-
cognitive assessment
- PROCEDURE
-
magnetic resonance imaging
- PROCEDURE
-
magnetic resonance spectroscopic imaging
- PROCEDURE
-
quality-of-life assessment
Sponsors & Collaborators
-
Children's Cancer and Leukaemia Group
lead OTHER
Principal Investigators
-
Martin W. English, MD · Birmingham Children's Hospital
Eligibility
- Max Age
- 2 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-04-30
- Primary Completion
- 2034-03-31
Countries
- United Kingdom
Study Locations
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