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Impact of Weight Loss Following Bariatric Surgery on Pulmonary Function in Patients With Morbid Obesity

NCT00532896 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2012-02-22

No results posted yet for this study

Summary

Increase in body mass index (BMI)is associated with a decrease in expiratory flows.Obesity is also associated with an increased prevalence of asthma.Consequences of obesity on respiratory function and on bronchial responsiveness are still to be documented.

This study aims to evaluate, before and after surgery, the impact of a bariatric surgery (biliopancreatic diversion with duodenal switch)on respiratory function in patients with morbid obesity .

Our hypothesis is that weight loss following bariatric surgery will induce significant improvements in pulmonary function and airway responsiveness, and, as a consequence, a reduction in respiratory symptoms,these changes being correlated with a reduction in systemic markers of inflammation. Maintenance of weight loss after one year will permit the persistence of these improvements

Conditions

Sponsors & Collaborators

  • Laval University

    lead OTHER

Principal Investigators

  • Louis-Philippe Boulet, MD · Hôpital Laval

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-04-30
Primary Completion
2011-01-31
Completion
2011-05-31

Countries

  • Canada

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00532896 on ClinicalTrials.gov