Molecular, Metabolomic and Nutritional Changes After Metabolic Surgery
NCT05322551 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 102
Last updated 2022-09-01
Summary
Obesity is a major risk factor for Type 2 Diabetes (T2D) and cardiovascular diseases, such as hypertension and dyslipidemia. Recently, weight loss surgery (i.e., metabolic or bariatric surgery) has been shown to result in very good long-term glycemic control in patients with T2D and obesity. However, knowledge and data on molecular levels and metabolomics are still limited. This study will fill in these gaps and provide potential biomarkers for T2D. Lifestyle and dietary practices (LDP) influence the clinical outcome and metabolites in T2D. Although the roles of LDP is critical in ensuring optimal clinical outcomes, data is still limited especially on relating the LDP and metabolomics in T2D.
Conditions
- Obesity; Endocrine
- Diabete Type 2
- PreDiabetes
Sponsors & Collaborators
-
Universiti Putra Malaysia
collaborator OTHER -
Ministry of Health, Malaysia
lead OTHER_GOV
Principal Investigators
-
Fazliana Mansor, PhD · Institute for Medical Research, Setia Alam, Malaysia
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-06-24
- Primary Completion
- 2023-01-31
- Completion
- 2024-12-31
Countries
- Malaysia
Study Locations
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