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Folate Augmentation of Treatment - Evaluation for Depression: a Randomised Controlled Trial

NCT00514410 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 730

Last updated 2011-10-12

No results posted yet for this study

Summary

To determine whether giving folic acid to people with depression will help their antidepressants work better. If folate does help antidepressants to work better, then it will provide a safe, simple and cheap way of improving the treatment of depression.

Conditions

Interventions

DRUG

Folic Acid

Folic acid 5 mg once a day for three months as a supplement to their antidepressant treatment

DRUG

Placebo

Matching placebo taken once a day for three months

Sponsors & Collaborators

  • NHS Health Technology Assessment Programme

    collaborator OTHER

  • Swansea University

    collaborator OTHER

  • Cardiff University

    collaborator OTHER

  • University of Liverpool

    collaborator OTHER

  • North West Wales NHS Trust

    collaborator OTHER

  • North East Wales NHS Trust

    collaborator OTHER

  • Swansea NHS Trust

    collaborator OTHER_GOV

  • Bangor University

    lead OTHER

Principal Investigators

  • Ian T Russell, PhD, HonFRCGP, FRCP Edin, FFPH · Swansea University

  • Keith Lloyd, MBBS, MSc, MRC Psych, MSc, MD · Swansea University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-07-31
Primary Completion
2011-05-31
Completion
2011-05-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00514410 on ClinicalTrials.gov