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PREconception Folic Acid Clinical Efficacy (PREFACE) Trial

NCT06641245 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 272

Last updated 2024-10-21

No results posted yet for this study

Summary

A study to help understand what forms of folic acid are most effective to increase folate status during pregnancy for the best protection against neural tube defects

Conditions

  • Folate
  • Folate Bioavailability
  • Clinical Trials
  • Pregnancy

Interventions

DIETARY_SUPPLEMENT

Folic Acid

folic acid (0.6 mg)

DIETARY_SUPPLEMENT

5-MTHF (5-methyltetrahydrofolate)

0.625 mg/d (6S)-5-MTHF

Sponsors & Collaborators

  • University of Saskatchewan

    collaborator OTHER

  • University of British Columbia

    lead OTHER

Principal Investigators

  • Crystal D Karakochuk, PhD · The University of British Columbia

  • Kelsey M Cochrane, PhD · University of Saskatchewan

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
19 Years
Max Age
42 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-01-31
Primary Completion
2029-01-31
Completion
2030-01-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06641245 on ClinicalTrials.gov