Evaluating the Role of Thrombin in Saphenous Vein Graft Failure After Heart Bypass Surgery
NCT00481806 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 450
Last updated 2013-05-10
Summary
Heart bypass surgery, also known as coronary artery bypass graft (CABG) surgery, creates a detour around the blocked part of a heart artery to restore blood supply to the heart muscle. The saphenous vein, located along the inside of the leg, is commonly used to create the bypass in a CABG surgery. An abnormal increase in the blood clotting protein thrombin may cause the saphenous vein graft to close up and eventually fail. This study will evaluate the relationship between thrombin levels and saphenous vein graft failures in people undergoing a CABG procedure.
Conditions
- Coronary Artery Bypass
- Thrombosis
Sponsors & Collaborators
-
University of Maryland, Baltimore County
collaborator OTHER -
University of Arizona
lead OTHER
Principal Investigators
-
Robert S. Poston, MD · University of Arizona, Tucson
Eligibility
- Min Age
- 18 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-02-28
- Primary Completion
- 2013-05-31
- Completion
- 2013-12-31
Countries
- United States
Study Locations
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