Cholesterol and Pharmacogenetic Study
NCT00451828 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 1000
Last updated 2011-10-05
Summary
The overall objective of the CAP study was to determine genetic influences on efficacy of simvastatin treatment with regard to LDL cholesterol reduction and changes in other markers of cardiovascular disease risk.
Conditions
Interventions
- DRUG
-
Simvastatin
40mg/day
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
collaborator NIH -
San Francisco General Hospital
collaborator OTHER -
University of California, Los Angeles
collaborator OTHER -
Cedars-Sinai Medical Center
collaborator OTHER - collaborator OTHER
- collaborator OTHER
-
UCSF Benioff Children's Hospital Oakland
lead OTHER
Principal Investigators
-
Ronald M Krauss, M.D. · UCSF Benioff Children's Hospital Oakland
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 30 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2002-03-31
- Primary Completion
- 2004-10-31
Countries
- United States
Study Locations
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