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Genetically Guided Statin Therapy

NCT01894230 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 167

Last updated 2017-06-23

Study results available
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Summary

The purpose of this study is to examine if using genetics can improve statin adherence in patients who should be taking statins but are not because of prior side effects. This study will assist physicians/providers in making a personalized health care plan for prevention of cardiovascular disease.

Conditions

  • Hypercholesterolemia
  • Hydroxy-methylglutaryl-coenzyme A (HMG Co-A) Reductase Inhibitors Adverse Reaction

Interventions

GENETIC

SLCO1B1*5 allele testing, results reported at randomization

Genetic testing for SLCO1B1\*5 allele and reporting of results to patient and provider at randomization

GENETIC

SLCO1B1*5 allele testing, results reported at end of study

Genetic testing for SLCO1B1\*5 allele and reporting of results to patient and provider at end of study

GENETIC

Genetic testing for SLCO1B1*5 allele

Blood test for SLCO1B1\*5 allele

Sponsors & Collaborators

  • David Grant U.S. Air Force Medical Center

    collaborator FED

  • Duke University

    lead OTHER

Principal Investigators

  • Deepak Voora, MD · Duke University

  • Henry Lau, MD · David Grant US Air Force Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-07-31
Primary Completion
2016-04-30
Completion
2016-04-30

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01894230 on ClinicalTrials.gov