MedTrace Logo

Low Dose Vasopressin in Traumatic Shock

NCT00420407 · Status: TERMINATED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 81

Last updated 2019-06-18

Study results available
· View outcomes & findings →

Summary

Hypothesis: We hypothesize that resuscitation regimens which minimize the total volume of resuscitation fluid, while restoring organ perfusion, will lead to lower morbidity and mortality in critically ill patients following trauma.

Conditions

  • Injuries
  • Shock, Traumatic

Interventions

DRUG

normal saline control

no vasopressin added to bolus or 5 hour continuous infusion

DRUG

vasopressin

vasopressin bolus 4 units followed by continuous infusion 2.4units/hr for 5 hours

Sponsors & Collaborators

  • The University of Texas Health Science Center at San Antonio

    lead OTHER

Principal Investigators

  • Stephen M. Cohn, MD · The University of Texas Health Science Center at San Antonio

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-02-28
Primary Completion
2009-04-30
Completion
2011-02-28
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00420407 on ClinicalTrials.gov