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Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure

NCT05355974 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 42

Last updated 2024-07-15

No results posted yet for this study

Summary

The purpose of this study is to investigate whether protocolized vasopressor use for patients with normal blood pressure undergoing rapid sequence intubation improves hemodynamic parameters and mitigates adverse events.

The hypothesis is that use of vasopressors during Rapid Sequence Intubation will prevent substantial decreases in blood pressure when compared to normal intravenous fluids.

Conditions

  • Respiratory Failure
  • Hypotension and Shock
  • Hypotension on Induction
  • Intubation Complication
  • Anesthesia Intubation Complication

Interventions

DRUG

Norepinephrine

Norepinephrine continuous infusion at 0.10 mcg/kg/min

DRUG

Lactated Ringers, Intravenous

500mL infusion run at 999mL/hr

DRUG

normal saline

500mL infusion run at 999mL/hr

DRUG

Plasma-lyte

500mL infusion run at 999mL/hr

Sponsors & Collaborators

  • Wright State University

    lead OTHER

Principal Investigators

  • Matthew Koroscil, MD · Wright State University

  • Yonatan Dollin, DO · Wright State University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-08-09
Primary Completion
2024-07-10
Completion
2024-07-10
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05355974 on ClinicalTrials.gov