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Is Dexmedetomidine Associated With a Lower Incidence of Postoperative Delirium When Compared to Propofol or Midazolam in Cardiac Surgery Patients

NCT00417664 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2022-05-27

No results posted yet for this study

Summary

The purpose of this chart review study is to determine whether the use of dexmedetomidine, a selective α2-adrenergic receptor agonist with sedative, analgesic, and antinociceptive properties, would be associated with a lower incidence of delirium when compared to propofol and midazolam. We hypothesize that sedation with dexmedetomidine following cardiac surgery with CPB will be associated with a lower incidence of postoperative delirium.

Conditions

  • Delirium

Interventions

DRUG

Dexmedetomidine

Dexmedetomidine administered as part of anesthesia in cardiac surgery patients

DRUG

Propofol

Propofol administered as part of anesthesia in cardiac surgery patients

DRUG

Midazolam

Midazolam administered as part of anesthesia in cardiac surgery patients

Sponsors & Collaborators

Principal Investigators

  • Jose R Maldonado, MD · Stanford University

Eligibility

Min Age
18 Years
Max Age
89 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2002-04-30
Primary Completion
2004-01-31
Completion
2004-04-30
FDA Drug
Yes

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00417664 on ClinicalTrials.gov