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Randomized Trial of a Liberal Versus a Restrictive Transfusion Strategy in Elderly Cardiac Surgery Patients

NCT00318227 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 73

Last updated 2017-08-28

No results posted yet for this study

Summary

The purpose of this study is to determine whether a less restrictive strategy of red blood cell transfusion in elderly patients following coronary bypass surgery results in enhanced postoperative recovery as determined by quality of life assessment, exercise tolerance and clinical outcomes.

Two postoperative transfusion strategies:

1. Liberal - transfused when Hgb is \<100g/L
2. Restrictive - transfused when Hgb is \<70g/L

Conditions

  • Anemia
  • Coronary Artery Bypass Surgery

Interventions

PROCEDURE

Blood Transfusion

Blood transfusion will be administered when the transfusion trigger is met.

Sponsors & Collaborators

  • London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

    lead OTHER

Principal Investigators

  • Mary Lee Myers, MD FRCSC · London Health Sciences Centre/University of Western Ontario

  • Robin Varghese, MD MS FRCSC · London Health Sciences Centre/University of Western Ontario

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
70 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-06-21
Primary Completion
2009-04-21
Completion
2010-02-23

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00318227 on ClinicalTrials.gov