Randomized Placebo-Controlled Trial (RPCT) of Maize/Zinc in Guatemala

Summary

Malnutrition is a serious health problem in the developing world. This study looks at the effects of changing the type of basic food staple (corn) used in Guatemala and infant zinc supplementation on infants' growth, development, and illnesses from infectious diseases.

Conditions

• Nutrition
• Pregnancy

Interventions

DRUG

Low phytic acid maize

DRUG

Zinc

Sponsors & Collaborators

• Global Network for Women's and Children's Health Research

  collaborator OTHER

• Bill and Melinda Gates Foundation

  collaborator OTHER

• Fogarty International Center of the National Institute of Health

  collaborator NIH

• National Center for Complementary and Integrative Health (NCCIH)

  collaborator NIH

• National Institute of Dental and Craniofacial Research (NIDCR)

  collaborator NIH

• National Cancer Institute (NCI)

  collaborator NIH

• RTI International

  collaborator OTHER

• University of Colorado, Denver

  collaborator OTHER

• Center for Studies of Sensory Impairment, Aging and Metabolism

  collaborator OTHER

• Foundation for Alimentation and Nutrition, Central America and Panama

  collaborator OTHER

• USDA Beltsville Human Nutrition Research Center

  collaborator FED

• NICHD Global Network for Women's and Children's Health

  lead NETWORK

Principal Investigators

• Michael Hambidge, MD · University of Colorado, Denver

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Max Age

40 Years

Sex

FEMALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2003-03-31

Completion

2007-04-30

Countries

• Guatemala

Study Locations