Vaccine Therapy Plus Biological Therapy in Treating Adults With Metastatic Solid Tumors
NCT00019331 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2013-06-20
Summary
RATIONALE: Vaccines made from a peptide may make the body build an immune response to kill tumor cells. Combining vaccine therapy with interleukin-2 and/or sargramostim may be a more effective treatment for solid tumors.
PURPOSE: Phase II trial to study the effectiveness of vaccine therapy plus interleukin-2 and/or sargramostim in treating adults who have metastatic solid tumors.
Conditions
- Colorectal Cancer
- Endometrial Cancer
- Head and Neck Cancer
- Liver Cancer
- Lung Cancer
- Melanoma (Skin)
- Pancreatic Cancer
- Testicular Germ Cell Tumor
- Unspecified Adult Solid Tumor, Protocol Specific
Interventions
- BIOLOGICAL
-
aldesleukin
- BIOLOGICAL
-
ras peptide cancer vaccine
- BIOLOGICAL
-
sargramostim
- DRUG
-
DetoxPC
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Barry L. Gause, MD · National Cancer Institute (NCI)
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1997-10-31
- Completion
- 2007-05-31
Countries
- United States
Study Locations
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