Vaccine Therapy in Treating Patients With Colon, Pancreatic, or Lung Cancer
NCT00019006 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2024-03-04
Summary
RATIONALE: Vaccines made from mutated ras peptides may make the body build an immune response to and kill tumor cells.
PURPOSE: Phase I trial to study the effectiveness of a vaccine containing mutated ras peptides and an immune adjuvant in treating patients who have colon, pancreatic, or lung cancer.
Conditions
- Recurrent Colon Cancer
- Extensive Stage Small Cell Lung Cancer
- Stage III Pancreatic Cancer
- Stage III Rectal Cancer
- Limited Stage Small Cell Lung Cancer
- Recurrent Pancreatic Cancer
- Recurrent Rectal Cancer
- Stage III Non-small Cell Lung Cancer
- Stage I Pancreatic Cancer
- Stage II Non-small Cell Lung Cancer
- Stage IVB Pancreatic Cancer
- Stage II Pancreatic Cancer
- Stage III Colon Cancer
- Stage IVA Pancreatic Cancer
Interventions
- DRUG
-
Detox-B adjuvant
- DRUG
-
ras peptide cancer vaccine
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Samir N. Khleif · National Cancer Institute (NCI)
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1995-03-31
Countries
- United States
Study Locations
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