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Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm

NCT00012480 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 400

Last updated 2015-04-15

No results posted yet for this study

Summary

Our data indicate that environmental exposure to the heavy metal lead are more widespread than currently appreciated and that such exposures are associated with the production of human male subfertility. Lead's effects are observed in male partners of infertile couples attending an IVF clinical, in men acting as semen donors in an artificial insemination program and in men representative of the general public. Our goal is to identify the mechanism(s) underlying lead's anti-fertility action.

Conditions

  • Male Infertility
  • Testicular Diseases
  • Urologic and Male Genital Diseases
  • Lead Poisoning

Sponsors & Collaborators

  • National Institute of Environmental Health Sciences (NIEHS)

    lead NIH

Principal Investigators

  • Susan H Benoff, PhD · North Shore University Hospital

Eligibility

Min Age
21 Years
Max Age
55 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2002-08-31
Primary Completion
2007-07-31
Completion
2007-07-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00012480 on ClinicalTrials.gov