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Effects of Atorvastatin on Human Semen and Gonadal Hormones

NCT02094313 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 17

Last updated 2014-03-21

No results posted yet for this study

Summary

Recently, concerns about the effect of atorvastatin intake on men fertility have been raised. However, this statin has never been investigated regarding its influence on male fertility, notably sperm quality.

The aim of this pilot study is to evaluate the efficacy and the safety of a decrease of cholesterol blood levels, induced by taking atorvastatin, on sperm quality of normocholesterolaemic and healthy men without confounding factors.

Conditions

  • Healthy Volunteers
  • Normocholesterolaemic Men
  • Normozoospermic Men

Interventions

DRUG

Atorvastatin

The aim of this pilot study is to evaluate the efficacy and the safety of a decrease of cholesterol blood levels, induced by taking atorvastatin, on sperm quality of normocholesterolaemic and healthy men without confounding factors.

Sponsors & Collaborators

  • Service de Biologie de la Reproduction : AMP-CECOS

    collaborator UNKNOWN

  • EA 975, Laboratoire de BDR

    collaborator UNKNOWN

  • Service d'Endocrinologie, Diabète et Maladies Métaboliques

    collaborator UNKNOWN

  • Laboratoire d'Hormonologie - Biochimie

    collaborator UNKNOWN

  • University Hospital, Clermont-Ferrand

    lead OTHER

Principal Investigators

  • Igor TAUVERON · University Hospital, Clermont-Ferrand

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-01-31
Primary Completion
2014-01-31
Completion
2014-01-31

Countries

  • France

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02094313 on ClinicalTrials.gov