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Oxidative Stress and Lipidomics in Male Infertility

NCT02062229 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2015-12-11

No results posted yet for this study

Summary

Infertility is a common problem, affecting perhaps one couple in six, the majority of whom now seek medical care. It is becoming a social challenge because it is responsible for personal and interpersonal discomfort and anxiety. A major obstacle to meaningful study of the epidemiology of male infertility is the difficulty in accurate diagnosis of the presence or absence of a problem. Traditionally, the diagnosis of male infertility is facilitated by the conventional assessment of the semen profile - constructed according to recognized guidelines (i.e. WHO) and including pH, cell count and motility - but no specific biomarkers are available.

We sought to determine the oxysterol and fatty acid lipidome with the ai of finding a lipid biomarker useful for the diagnosis of male infertility.

Conditions

  • Male Infertility

Sponsors & Collaborators

  • Civic Hospital, Italy

    collaborator OTHER

  • University of Roma La Sapienza

    lead OTHER

Principal Investigators

  • Rocco Rago, M.D. · Civic Hospital

  • Luigi Iuliano, M.D. · University of Roma La Sapienza

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-02-29
Primary Completion
2013-10-31
Completion
2016-06-30

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02062229 on ClinicalTrials.gov