Oltipraz in the Prevention of Lung Cancer in People Who Smoke
NCT00006457 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2012-06-11
Summary
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development of cancer.
PURPOSE: Randomized phase I trial to study the effectiveness of oltipraz in preventing lung cancer in people who smoke.
Conditions
Interventions
- DRUG
-
oltipraz
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH - lead OTHER
Principal Investigators
-
Raymond C. Bergan, MD · Robert H. Lurie Cancer Center
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- DOUBLE
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-08-31
- Primary Completion
- 2004-04-30
- Completion
- 2004-04-30
Countries
- United States
Study Locations
More Related Trials
-
Clinical Trial of Lung Cancer Chemoprevention With Sulforaphane in Former Smokers
NCT03232138 ·Status: COMPLETED ·Phase: PHASE2
-
Captopril in Treating Patients With Non-Small Cell Lung Cancer or Limited-Stage Small Cell Lung Cancer That Has Been Previously Treated With Radiation Therapy With or Without Chemotherapy
NCT00077064 ·Status: TERMINATED ·Phase: PHASE2
-
Minocycline for Reduction of Radiation Therapy Treatment-Related Symptom Burden in Oropharynx Cancer: A Randomized Study.
NCT01173692 ·Status: COMPLETED ·Phase: PHASE2
-
Radiation Therapy, Chemotherapy, and Soy Isoflavones in Treating Patients With Stage IIIA-IIIB Non-Small Cell Lung Cancer
NCT01958372 ·Status: COMPLETED ·Phase: PHASE1
-
The Study Of An Oral Drug Called A Radiation Sensitizer In Patients With Newly Diagnosed Small Cell Lung Cancer (SCLC)
NCT00043862 ·Status: COMPLETED ·Phase: PHASE2
-
A Study To Test The Impact Of PF- 00299804 On How The Body Handles Dextromethorphan In Cancer Patients
NCT00728468 ·Status: COMPLETED ·Phase: PHASE1
-
ACAPHA in Preventing Lung Cancer in Former Smokers With Bronchial Intraepithelial Neoplasia
NCT00522197 ·Status: COMPLETED ·Phase: PHASE2
-
Green Tea Extract in Treating Current or Former Smokers With Bronchial Dysplasia
NCT00611650 ·Status: TERMINATED ·Phase: PHASE2
-
Indole-3-Carbinol in Preventing Breast Cancer in Nonsmoking Women Who Are at High Risk For Breast Cancer
NCT00033345 ·Status: COMPLETED ·Phase: PHASE1
-
Inositol in Preventing Lung Cancer in Patients With Bronchial Epithelial Dysplasia Who Are Current or Former Smokers
NCT00061997 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Non-small Cell Lung Cancer (NSCLC), Ovarian Cancer, or Breast Cancer
NCT03937154 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Radiation Therapy Plus Topotecan in Treating Patients With Non-small Cell Lung Cancer
NCT00002537 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I, Open-label Study to Assess Bioavailability of a Single Oral Dose of AZD9291 vs an IV Dose of [14C]AZD9291
NCT02491944 ·Status: COMPLETED ·Phase: PHASE1
-
Carcinogenicity Study of Bupropion
NCT01077596 ·Status: COMPLETED
-
Open-Label Extension and Safety Study of Talazoparib
NCT02921919 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Trial of Metastasis Inhibitor NP-G2-044 in Patients With Advanced or Metastatic Treatment-Refractory Solid Tumor Malignancies
NCT03199586 ·Status: COMPLETED ·Phase: PHASE1
-
Effects of Vitamin D in Patients With Breast Cancer
NCT01948128 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase I Study of Infusional Chemotherapy With the P-Glycoprotein Antagonist PSC 833
NCT00001302 ·Status: COMPLETED ·Phase: PHASE1
-
Resveratrol in Healthy Adult Participants
NCT00721877 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Cytoreductive Surgery and Hyperthermic Intrathoracic Pleural Chemotherapy (HITC) With Escalating Doses for Children and Adolescents With Unilateral Pleural Malignancy
NCT01998529 ·Status: COMPLETED ·Phase: PHASE1
-
Amifostine, Chemotherapy, and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer
NCT00004176 ·Status: COMPLETED ·Phase: PHASE2
-
To Evaluate the QoL Improvement of Oral Oligo Fucoidan in Subjects Receiving Platinum-based Chemotherapy With NSCLC
NCT03130829 ·Status: WITHDRAWN ·Phase: NA
-
Safety of Batracylin in Patients With Solid Tumors and Lymphomas
NCT00450502 ·Status: COMPLETED ·Phase: PHASE1
-
Ph 1 Trial of ADI-PEG 20 Plus Docetaxel in Solid Tumors With Emphasis on Prostate Cancer and Non-Small Cell Lung Cancer
NCT01497925 ·Status: COMPLETED ·Phase: PHASE1
-
Rapamycin With Grapefruit Juice for Advanced Malignancies
NCT00375245 ·Status: COMPLETED ·Phase: PHASE1