MedTrace Logo

Rapamycin With Grapefruit Juice for Advanced Malignancies

NCT00375245 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 41

Last updated 2014-01-17

No results posted yet for this study

Summary

The purpose of this study is to determine the highest safe dose of rapamycin when given with a fixed amount of grapefruit juice.

Conditions

Interventions

DRUG

Rapamycin (sirolimus)

Weekly oral doses, dose is assigned at the time of study entry

OTHER

Grapefruit Juice

Daily oral doses starting during the second week on study.

Sponsors & Collaborators

  • University of Chicago

    lead OTHER

Principal Investigators

  • Ezra W Cohen, MD · University of Chicago

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-09-30
Primary Completion
2009-05-31
Completion
2012-05-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00375245 on ClinicalTrials.gov