Clinical Trials Updated in 2026

NCT05319444 | TERMINATED | NA

2 participants

Cleansing Device for the Treatment of Scalp and Hair Conditions

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-05-27
Completion:: 2023-05-12

Conditions

Dandruff
Seborrheic Dermatitis
Hair Loss

Interventions

DEVICE

Results Available

NCT05315700 | RECRUITING | PHASE1/PHASE2

350 participants

Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-03-10
Completion:: 2026-09-30

Conditions

Solid Tumors

Interventions

DRUG

No Results Yet

NCT05314088 | COMPLETED | NA

82 participants

Testing the Efficacy and Mechanisms of an Adapted Resilience Building Intervention in People Aging With HIV

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2023-02-03
Completion:: 2025-05-31

Conditions

Resilience
HIV-1-infection
Stress, Psychological

Interventions

BEHAVIORAL

Results Available

NCT05281380 | COMPLETED | NA

107 participants

VITAMin Insufficiency in Esophagogastric Neoplasms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2021-12-01
Completion:: 2024-12-31

Conditions

Esophageal Cancer
Gastric Cancer
Vitamin Disease
Quality of Life

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05275868 | TERMINATED | PHASE1

41 participants

Study of MGY825 in Patients With Advanced Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-10-05
Completion:: 2025-10-13

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05271409 | ACTIVE_NOT_RECRUITING | PHASE3

132 participants

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-08-30
Completion:: 2025-11-20

Conditions

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)

Interventions

DRUG
OTHER

No Results Yet

NCT05238519 | COMPLETED | PHASE3

257 participants

Improved Diagnosis of Familial Hypercholesterolemia Across the Northland (ID-FH)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-02-15
Completion:: 2024-11-06

Conditions

Familial Hypercholesterolemia
Cholesterol, Elevated
Genetic Disease

Interventions

BEHAVIORAL

No Results Yet

NCT05231824 | COMPLETED | NA

301 participants

Using Artificial Intelligence to Optimize Delivery of Weight Loss Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-03-22
Completion:: 2025-02-28

Conditions

Obesity
Weight Loss

Interventions

BEHAVIORAL

No Results Yet

NCT05215327 | ACTIVE_NOT_RECRUITING | PHASE2

270 participants

High vs. Standard Dose Influenza Vaccine in Lung Allograft Recipients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-11-08
Completion:: 2027-07-31

Conditions

Immunization; Infection
Transplantation Infection
Influenza

Interventions

BIOLOGICAL

No Results Yet

NCT05204927 | ACTIVE_NOT_RECRUITING | PHASE3

439 participants

177Lu-PSMA-I&T for Metastatic Castration-Resistant Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-02-14
Completion:: 2024-08-02

Conditions

Metastasis From Malignant Tumor of Prostate

Interventions

DRUG

No Results Yet

NCT05198830 | ACTIVE_NOT_RECRUITING | PHASE2

42 participants

Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-12-15
Completion:: 2027-06-30

Conditions

Lung Adenocarcinoma
Lung Large Cell Carcinoma
Lung Non-Squamous Non-Small Cell Carcinoma
Stage III Lung Cancer AJCC v8

Interventions

DRUG
PROCEDURE
BIOLOGICAL
RADIATION

No Results Yet

NCT05198674 | ACTIVE_NOT_RECRUITING | NA

1899 participants

SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2021-10-20
Completion:: 2026-03-05

Conditions

Hypertension
Vascular Diseases
Cardiovascular Diseases
Chronic Kidney Diseases
Diabetes Mellitus

Interventions

DEVICE

No Results Yet

NCT05192798 | RECRUITING | PHASE2

128 participants

Albumin-Bound Paclitaxel Combined With Antiangiogenic Agents in First-line Treatment of Relapsed or Metastatic TNBC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-01-14
Completion:: 2027-09-10

Conditions

Triple-negative Breast Cancer

Interventions

DRUG

No Results Yet

NCT05189925 | RECRUITING | PHASE1

25 participants

NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-07-22
Completion:: 2027-07-01

Conditions

Chronic Granulomatous Disease
Infection

Interventions

BIOLOGICAL

No Results Yet

NCT05163314 | TERMINATED | PHASE3

352 participants

A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-03-04
Completion:: 2025-09-24

Conditions

Dravet Syndrome (DS)
Lennox Gastaut Syndrome (LGS)

Interventions

DRUG

Results Available

NCT05142267 | COMPLETED | PHASE4

101 participants

Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-03-02
Completion:: 2026-02-16

Conditions

Opioid Use Disorder
Back Pain
Stress

Interventions

DRUG

No Results Yet

NCT05139368 | ACTIVE_NOT_RECRUITING | NA

22 participants

Hypofractionated Radiotherapy for the Treatment of Cervical or Endometrial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2021-11-11
Completion:: 2024-07-17

Conditions

Cervical Carcinoma
Endometrial Carcinoma

Interventions

RADIATION

Results Available

NCT05136196 | RECRUITING | PHASE2

150 participants

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-12-06
Completion:: 2027-01-01

Conditions

Clinical Stage III Cutaneous Melanoma AJCC v8
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Clinical Stage IV Cutaneous Melanoma AJCC v8
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Locally Recurrent Head and Neck Squamous Cell Carcinoma
Locally Recurrent Hypopharyngeal Squamous Cell Carcinoma
Locally Recurrent Laryngeal Squamous Cell Carcinoma
Locally Recurrent Oral Cavity Squamous Cell Carcinoma
Locally Recurrent Oropharyngeal Squamous Cell Carcinoma
Metastatic Head and Neck Squamous Cell Carcinoma
Metastatic Hypopharyngeal Squamous Cell Carcinoma
Metastatic Laryngeal Squamous Cell Carcinoma
Metastatic Melanoma
Metastatic Oral Cavity Squamous Cell Carcinoma
Metastatic Oropharyngeal Squamous Cell Carcinoma
Recurrent Melanoma
Stage III Hypopharyngeal Carcinoma AJCC v8
Stage III Laryngeal Cancer AJCC v8
Stage III Lip and Oral Cavity Cancer AJCC v8
Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage IV Hypopharyngeal Carcinoma AJCC v8
Stage IV Laryngeal Cancer AJCC v8
Stage IV Lip and Oral Cavity Cancer AJCC v8
Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Unresectable Melanoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT05112601 | RECRUITING | PHASE2

81 participants

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-06-02
Completion:: 2032-07-30

Conditions

Endometrial Adenocarcinoma
Endometrial Clear Cell Adenocarcinoma
Endometrial Dedifferentiated Carcinoma
Endometrial Endometrioid Adenocarcinoma
Endometrial Mixed Cell Adenocarcinoma
Endometrial Mucinous Adenocarcinoma
Endometrial Undifferentiated Carcinoma
Endometrioid Adenocarcinoma
Recurrent Endometrial Carcinoma

Interventions

PROCEDURE
BIOLOGICAL

No Results Yet

NCT05108298 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

500 participants

Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2021-11-10
Completion:: 2027-05-01

Conditions

Hematopoietic and Lymphatic System Neoplasm
Malignant Solid Neoplasm

Interventions

OTHER

No Results Yet

NCT05099003 | RECRUITING | PHASE1/PHASE2

132 participants

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-05-31
Completion:: 2027-06-30

Conditions

Malignant Glioma

Interventions

PROCEDURE
RADIATION
DRUG

No Results Yet

NCT05084352 | COMPLETED

1200 participants

Real Time Vital Sign Assessment to Predict Neurological Decline After Traumatic Brain Injury

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-04
Start Date:: 2021-03-29
Completion:: 2026-08-31

Conditions

Traumatic Brain Injury

No Results Yet

NCT05049174 | COMPLETED | NA

221 participants

Nurse-led Smoking Cessation Program With Follow-up in Healthy Life Centres: a Randomized Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2021-11-01
Completion:: 2024-10-31

Conditions

Smoking Cessation
Smoking Behaviors
Nurse's Role
Cardiovascular Diseases

Interventions

BEHAVIORAL

No Results Yet

NCT05041127 | ACTIVE_NOT_RECRUITING | PHASE2

29 participants

Cetuximab for the Treatment of Advanced Unresectable or Metastatic Chordoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-05-27
Completion:: 2028-09-01

Conditions

Chordoma
Metastatic Chordoma
Unresectable Chordoma

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT05027386 | COMPLETED | PHASE1/PHASE2

125 participants

Apatinib Mesylate Combined With IT Regimen for the Treatment of Recurrent or Refractory Neuroblastoma: A Single-arm, Phase I/II，Multi-center, Clinical Study.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2021-08-26
Completion:: 2026-02-04

Conditions

Neuroblastoma

Interventions

DRUG

No Results Yet

NCT05020184 | COMPLETED | PHASE2

26 participants

Effect of Oral Cimetidine in the Protoporphyrias

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-06-14
Completion:: 2025-04-24

Conditions

Erythropoietic Protoporphyria
X-linked Protoporphyria

Interventions

DRUG

Results Available

NCT05016466 | COMPLETED

236 participants

GOLD 0 - DLCO 1: A Look Beyond the Obstruction. Is Spirometry Enough for COPD (Chronic Obstructive Pulmonary Disease) Screening?

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-04
Start Date:: 2021-09-10
Completion:: 2025-02-10

Conditions

COPD, Chronic Obstructive Pulmonary Disease

Interventions

OTHER

No Results Yet

NCT05010564 | RECRUITING | PHASE1

38 participants

Trivalent CAR-T Cell in Acute B-Lineage Leukemia (TRICAR-ALL)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2023-07-18
Completion:: 2028-07-16

Conditions

Leukemia, B-Cell

Interventions

GENETIC

No Results Yet

NCT05010122 | RECRUITING | PHASE1/PHASE2

42 participants

ASTX727, Venetoclax, and Gilteritinib for the Treatment of Newly Diagnosed, Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2021-07-08
Completion:: 2028-01-30

Conditions

Acute Myeloid Leukemia
Myelodysplastic Syndrome
Recurrent Acute Myeloid Leukemia
Refractory Acute Myeloid Leukemia

Interventions

DRUG

No Results Yet

NCT05008133 | COMPLETED

25 participants

Mapping of Cardiac Power in Healthy Humans and Testing of a New Blood Pressure Sensor

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-04
Start Date:: 2021-09-13
Completion:: 2021-11-04

Conditions

Healthy Volunteers

Interventions

BEHAVIORAL

No Results Yet

NCT04999124 | COMPLETED | NA

1762 participants

Characteristics of NAFLD Among Type 2 Diabetes Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2020-01-01
Completion:: 2026-06-30

Conditions

Non-Alcoholic Fatty Liver Disease
Type2 Diabetes

Interventions

OTHER

No Results Yet

NCT04992624 | RECRUITING | PHASE2

200 participants

Cannabinoid Interactions With Central and Peripheral Pain Mechanisms in Osteoarthritis of the Knee

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-02-22
Completion:: 2027-03-22

Conditions

Osteoarthritis, Knee
Osteoarthritis of the Knee

Interventions

DRUG

No Results Yet

NCT04991870 | RECRUITING | PHASE1

25 participants

Phase I CB-NK-TGF-ßR2-/NR3C1- in rGBM

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2023-04-28
Completion:: 2027-01-31

Conditions

Recurrent Gliosarcoma
Recurrent Supratentorial Glioblastoma
Supratentorial Gliosarcoma

Interventions

BIOLOGICAL
PROCEDURE

No Results Yet

NCT04976322 | ENROLLING_BY_INVITATION | PHASE3

760 participants

A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2021-07-27
Completion:: 2030-08-07

Conditions

Systemic Lupus Erythematosus

Interventions

DRUG

No Results Yet

NCT04950309 | RECRUITING | NA

100 participants

Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) Array

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2022-05-12
Completion:: 2027-08-01

Conditions

Normal Physiology

Interventions

DEVICE

No Results Yet

NCT04947865 | COMPLETED | NA

54 participants

Reflex Excitability in Post-stroke Stiff-Knee Gait

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2021-06-11
Completion:: 2025-06-11

Conditions

Stroke
Chronic Stroke
Gait, Hemiplegic
Gait, Spastic
Gait Disorder, Sensorimotor
Gait Disorders, Neurologic
Walking, Difficulty

Interventions

OTHER
DEVICE

No Results Yet

NCT04945707 | COMPLETED | PHASE2/PHASE3

65 participants

Impact of Intravenous Iron Repletion On Mechanisms of Exercise InTolerance in HFpEF (IRONMET-HFpEF)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2021-11-26
Completion:: 2026-06-25

Conditions

Iron-deficiency
Heart Failure With Preserved Ejection Fraction

Interventions

DRUG

No Results Yet

NCT04940624 | COMPLETED | PHASE3

144 participants

A Study of Soticlestat as an Add-on Therapy in Children and Young Adults With Dravet Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2021-10-28
Completion:: 2024-04-11

Conditions

Dravet Syndrome (DS)

Interventions

DRUG

Results Available

NCT04909164 | COMPLETED

1519 participants

The Prospective Non-randomized Case-control Study From Real-world Lung Cancer Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-04
Start Date:: 2021-06-15
Completion:: 2025-12-31

Conditions

Non-small Cell Lung Cancer (NSCLC)

Interventions

DRUG

No Results Yet

NCT04901195 | COMPLETED | PHASE3

658 participants

A Study to Test the Long-term Treatment of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-04
Start Date:: 2021-05-27
Completion:: 2026-07-22

Conditions

Hidradenitis Suppurativa

Interventions

DRUG

No Results Yet