Nurse-led Smoking Cessation Program With Follow-up in Healthy Life Centres: a Randomized Clinical Trial

Summary

A better understanding of how to incorporate effective smoking cessation measures into clinical practice is requested. In this is prospective, multi-center, randomized, open, blinded end-point (PROBE) trial, we assigned daily smokers hospitalized with an acute cardiac event 1:1 to an in-hospital nurse-led smoking cessation intervention with direct referral to further follow-up in the municipal healthy life-centres (intensive intervention) or to written information about smoking cessation and the municipal program (low-threshold intervention) . The primary outcome will be the smoking cessation rates between the groups at 6 months follow-up. Key secondary outcomes include a cost-effectiveness analysis of the intensive intervention and cessation rates at 3- and 12-months follow-up, the proportion who used nicotine replacement therapy and the proportion who attended the healthy-life center program between the two groups. We also assess effects of recurrent cardiovascular events and mortality after 12 months, two and five years follow-up. Exploratory analyses include new knowledge about the patient and system factors of importance for participation to healthy life-centers and for changes in smoking behaviour.

Conditions

• Smoking Cessation
• Smoking Behaviors
• Nurse's Role
• Cardiovascular Diseases

Interventions

BEHAVIORAL

Nuse-led interview and referral to municipal healthy life-centres

Usual care treatment and written information to patients and general practitionnaires about smoking cessation and the municipal healthy life-centres

Sponsors & Collaborators

• University of Oslo

  collaborator OTHER

• Oslo University Hospital

  collaborator OTHER

• Norwegian Directorate of Health

  collaborator OTHER_GOV

• Norwegian Institute of Public Health

  collaborator OTHER_GOV

• Vestre Viken Hospital Trust

  lead OTHER

Study Design

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2021-11-01

Primary Completion

2024-10-31

Completion

2026-08-01

Countries

• Norway