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GOLD 0 - DLCO 1: A Look Beyond the Obstruction. Is Spirometry Enough for COPD (Chronic Obstructive Pulmonary Disease) Screening?

NCT05016466 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 236

Last updated 2021-08-23

No results posted yet for this study

Summary

This is a multicenter observational prospective study in smokers or ex-smokers with cumulative exposure ≥ 10 a / p (years / pack) with respiratory symptoms and presenting a normal spirometry.

The patients who sign the corresponding informed consent, will undergo a DLCO and will be divided into two groups according to the result:

* Group I. Patients with DLCO \<80%.
* Group II Patients with DLCO≥80%.

Both groups will be followed for 5 years.

Conditions

  • COPD, Chronic Obstructive Pulmonary Disease

Interventions

OTHER

Standard Care

Patients will followed during 5 years, and only 2 visits , baseline and 5 years

OTHER

Standard Care plus oxidative stress study plus inflammation biomarkers study

Patients will followed during 5 years, Annual follo-up visits will be carried out during this period

Sponsors & Collaborators

  • Fundación para la Investigación del Hospital Clínico de Valencia

    lead OTHER

Principal Investigators

  • Cruz González, PhD · Hospital Clínico Universitario de Valencia

Eligibility

Min Age
18 Years
Max Age
99 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-09-10
Primary Completion
2025-02-10
Completion
2025-12-31

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05016466 on ClinicalTrials.gov