Clinical Trials Updated in 2026

NCT04858958 | COMPLETED | PHASE1

90 participants

Study of FURMONERTINIB in Patients With NSCLC Having Exon 20 Insertion Mutation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-08-10
Completion:: 2024-12-05

Conditions

NSCLC

Interventions

DRUG

No Results Yet

NCT04856722 | COMPLETED | NA

253 participants

Mini-PNL, RIRS, and ESWL for Treatment of Medium-Sized, High-Density, Non-Lower Pole, Renal Stones

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-04-05
Completion:: 2024-06-04

Conditions

Renal Stone
Percutaneous Nephrolithotomy
Retrograde Intrarenal Surgery
Extracorporeal Shockwave Lithotripsy

Interventions

PROCEDURE

No Results Yet

NCT04855552 | ACTIVE_NOT_RECRUITING | NA

22 participants

Telehealth Weight Loss Program for Breast Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-07-19
Completion:: 2027-07-31

Conditions

Cancer Survivors
Cancer of Breast
Body Weight
Overweight and Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT04835493 | ACTIVE_NOT_RECRUITING | NA

320 participants

Evaluating Telementoring for CHW-centered Diabetes Initiatives

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-09-01
Completion:: 2025-04-30

Conditions

Diabetes Mellitus, Type 2

Interventions

OTHER

No Results Yet

NCT04825782 | COMPLETED

15391 participants

MiMBa Pregnancy Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-02-22
Completion:: 2025-12-31

Conditions

Malaria in Pregnancy
Pregnancy Related
Congenital Anomaly

No Results Yet

NCT04812366 | RECRUITING | PHASE2

315 participants

Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-09-21
Completion:: 2027-06-01

Conditions

Prostate Cancer

Interventions

DRUG

No Results Yet

NCT04797299 | RECRUITING

526 participants

Prospective Evaluation of Breast-Conserving Surgery Alone in Low-Risk Ductal Carcinoma in Situ (DCIS)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-11-23
Completion:: 2030-11-30

Conditions

DCIS

No Results Yet

NCT04789018 | COMPLETED

118 participants

Enhanced Genetic Awareness and Genetic Evaluation for Men Through Technology, ENGAGEMENT Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-01-21
Completion:: 2022-06-02

Conditions

Prostate Carcinoma

Interventions

OTHER

No Results Yet

NCT04786067 | COMPLETED | PHASE4

25 participants

Use of DNA Testing to Help Transition Kidney Transplant Recipients to Belatacept-only Immunosuppression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-07-28
Completion:: 2025-07-10

Conditions

Kidney Transplant Immunosuppression

Interventions

DRUG

Results Available

NCT04776941 | RECRUITING | NA

414 participants

Expressive Writing for the Management of Stress in Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-08-07
Completion:: 2028-12-31

Conditions

Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT04775368 | COMPLETED | NA

598 participants

Fibromyalgia Syndrome in France: The Role of Assessment and Management of Sleep Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-04-01
Completion:: 2023-03-07

Conditions

Fibromyalgia

Interventions

OTHER

No Results Yet

NCT04774718 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

42 participants

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-09-14
Completion:: 2032-02-28

Conditions

ALK Fusion-positive Solid or CNS Tumors

Interventions

DRUG

No Results Yet

NCT04743141 | RECRUITING | PHASE3

600 participants

Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-04-28
Completion:: 2030-07-31

Conditions

Acute Treatment of Migraine

Interventions

DRUG

No Results Yet

NCT04738825 | ACTIVE_NOT_RECRUITING | NA

526 participants

Promoting HIV Risk Reduction Among People Who Inject Drugs: A Stepped Care Approach Using Contingency Management With PrEP Adherence and Support Services

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-10-04
Completion:: 2026-07-31

Conditions

Opioid-use Disorder
HIV Prevention Program

Interventions

BEHAVIORAL

No Results Yet

NCT04736706 | ACTIVE_NOT_RECRUITING | PHASE3

1854 participants

A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-04-14
Completion:: 2026-02-04

Conditions

Carcinoma, Renal Cell

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT04706026 | ACTIVE_NOT_RECRUITING | NA

18 participants

A Pilot Study of Local Anesthesia for Inguinal Hernia Surgery in Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-10-23
Completion:: 2026-08-31

Conditions

Inguinal Hernia
Anesthesia, Local

Interventions

OTHER

No Results Yet

NCT04675307 | COMPLETED

50 participants

Multimodal, Task-Aware Movement Assessment and Control: Clinic to the Home

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-02-17
Completion:: 2023-12-01

Conditions

Frailty

No Results Yet

NCT04649242 | RECRUITING | PHASE3

2100 participants

Randomized Study in Children and Adolescents With Migraine: Acute Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-01-15
Completion:: 2029-01-09

Conditions

Pediatric Migraine

Interventions

DRUG

No Results Yet

NCT04591951 | COMPLETED | NA

108 participants

Family Navigation to Improve ADHD Treatment Adherence for Minority Children

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-05-14
Completion:: 2026-07-30

Conditions

Attention Deficit Hyperactivity Disorder

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT04567303 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

177 participants

Study of Zifibancimig in Participants With Neovascular Age-related Macular Degeneration

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-10-28
Completion:: 2026-08-25

Conditions

Macular Degeneration

Interventions

DRUG
DEVICE

No Results Yet

NCT04550481 | ACTIVE_NOT_RECRUITING | PHASE2

35 participants

Role of Lisinopril in Preventing the Progression of Non-Alcoholic Fatty Liver Disease, RELIEF-NAFLD Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-05-11
Completion:: 2025-08-08

Conditions

Hepatocellular Carcinoma
Nonalcoholic Steatohepatitis

Interventions

PROCEDURE
DRUG
OTHER

Results Available

NCT04537871 | ACTIVE_NOT_RECRUITING

350 participants

Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-11-18
Completion:: 2027-05-25

Conditions

Acute Lymphoblastic Leukemia
Acute Myeloid Leukemia
Hematopoietic and Lymphoid Cell Neoplasm
Hodgkin Lymphoma
Myelodysplastic Syndrome
Non-Hodgkin Lymphoma
Plasma Cell Myeloma

Interventions

PROCEDURE
OTHER

No Results Yet

NCT04401020 | TERMINATED | PHASE1

47 participants

First-in-human Single Agent Study of SAR442257 in RRMM and RR-NHL

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-07-24
Completion:: 2024-03-02

Conditions

Neoplasm Malignant

Interventions

DRUG

No Results Yet

NCT04381897 | NOT_YET_RECRUITING | PHASE2

10 participants

Use of N-Acetylcysteine in the Treatment of Repetitive and Self-Injurious Behaviors in Cornelia de Lange Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-11-01
Completion:: 2027-05-01

Conditions

Cornelia de Lange Syndrome

Interventions

DRUG
OTHER

No Results Yet

NCT04367675 | ACTIVE_NOT_RECRUITING | PHASE1

44 participants

INO 5401 Vaccination in BRCA1/2 Mutation Carriers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-04-20
Completion:: 2026-12-31

Conditions

BRCA1/2 Mutation

Interventions

DRUG
DEVICE

No Results Yet

NCT04357080 | COMPLETED

266 participants

Factors Predicting Urethral Stricture Recurrence After Dorsal Onlay Augmented, Buccal Mucosal Graft Urethroplasty

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-07-15
Completion:: 2020-08-15

Conditions

Urethral Stricture

Interventions

PROCEDURE

No Results Yet

NCT04346134 | COMPLETED | NA

72 participants

Mini- Percutaneous Nephrolithotomy Versus Extracorporeal Shock Wave Lithotripsy for High Density Renal Stones

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-07-14
Completion:: 2020-12-01

Conditions

Renal Stone
Extracorporeal Shockwave Lithotripsy
Percutaneous Nephrolithotomy

Interventions

PROCEDURE

No Results Yet

NCT04336150 | COMPLETED | NA

80 participants

Pelvic Floor Muscle Contraction During Hypopressive Exercise in Women With Pelvic Floor Dysfunction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2019-02-10
Completion:: 2024-12-20

Conditions

Pelvic Floor Disorders

Interventions

OTHER

No Results Yet

NCT04324619 | ACTIVE_NOT_RECRUITING | NA

6000 participants

iLookOut for Child Abuse: Micro-learning to Improve Knowledge Retention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-04-10
Completion:: 2027-08-31

Conditions

Child Abuse

Interventions

OTHER

No Results Yet

NCT04321876 | ACTIVE_NOT_RECRUITING

778 participants

Evaluation of a Collaborative Behavioral Health Program Implementation in Primary Care

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2018-09-01
Completion:: 2024-01-31

Conditions

Depression

Interventions

BEHAVIORAL

No Results Yet

NCT04302259 | COMPLETED | NA

3 participants

Intelligent Spine Interface, Clinical (ISI-C)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-09-01
Completion:: 2025-06-30

Conditions

Spinal Cord Injury

Interventions

DEVICE

No Results Yet

NCT04261478 | RECRUITING | NA

458 participants

Endovascular Acute Stroke Intervention - Tandem OCclusion Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-08-31
Completion:: 2027-05-31

Conditions

Stroke, Acute
Carotid Stenosis
Carotid Artery Diseases

Interventions

DEVICE
DRUG

No Results Yet

NCT04248192 | ACTIVE_NOT_RECRUITING | PHASE1

8 participants

Evaluate the Safety, Immunologic, and Virologic Responses of Donor Derived (DD) HIV-Specific T-cells (HST) in HIV-infected Individuals Following Allogeneic Bone Marrow Transplantation (alloRESIST)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-05-01
Completion:: 2026-11-30

Conditions

HIV-Infected Individuals

Interventions

BIOLOGICAL

No Results Yet

NCT04230759 | ACTIVE_NOT_RECRUITING | PHASE2

180 participants

Radiochemotherapy +/- Durvalumab for Locally-advanced Anal Carcinoma. A Multicenter, Randomized, Phase II Trial of the German Anal Cancer Study Group

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-01-07
Completion:: 2026-12-31

Conditions

Anal Cancer
Anal Carcinoma
Anal Cancer Stage III
Anal Cancer Stage II

Interventions

DRUG
RADIATION

No Results Yet

NCT04221893 | RECRUITING | NA

28 participants

Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-08-07
Completion:: 2027-04-30

Conditions

Stage IV Esophageal Adenocarcinoma
Stage IV Esophageal Squamous Cell Carcinoma
Stage IV Gastric Cancer
Stage IV Adenocarcinoma of the Gastroesophageal Junction
Stage IVA Esophageal Adenocarcinoma
Stage IVA Esophageal Squamous Cell Carcinoma
Stage IVA Gastric Cancer
Stage IVA Adenocarcinoma of the Gastroesophageal Junction
Stage IVB Esophageal Adenocarcinoma
Stage IVB Esophageal Squamous Cell Carcinoma
Stage IVB Gastric Cancer
Stage IVB Gastroesophageal Junction Adenocarcinoma
Metastatic Anal Canal Carcinoma
Metastatic Colorectal Carcinoma
Metastatic Esophageal Carcinoma
Metastatic Gastric Carcinoma
Metastatic Gastroesophageal Junction Adenocarcinoma
Metastatic Hepatocellular Carcinoma
Metastatic Malignant Digestive System Neoplasm
Metastatic Small Intestinal Carcinoma
Pancreatobiliary Carcinoma
Pathologic Stage IV Gastric Cancer AJCC v8
Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8
Pathologic Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8
Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8
Pathologic Stage IVB Esophageal Squamous Cell Carcinoma AJCC v8
Pathologic Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
Postneoadjuvant Therapy Stage IV Esophageal Squamous Cell Carcinoma AJCC v8
Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8
Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
Postneoadjuvant Therapy Stage IVA Esophageal Adenocarcinoma AJCC v8
Postneoadjuvant Therapy Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8
Postneoadjuvant Therapy Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
Postneoadjuvant Therapy Stage IVB Esophageal Adenocarcinoma AJCC v8
Postneoadjuvant Therapy Stage IVB Esophageal Squamous Cell Carcinoma AJCC V8
Postneoadjuvant Therapy Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
Stage IV Anal Cancer AJCC v8
Stage IV Colorectal Cancer AJCC v8
Stage IV Hepatocellular Carcinoma AJCC v8
Stage IVA Colorectal Cancer AJCC v8
Stage IVA Hepatocellular Carcinoma AJCC v8
Stage IVB Colorectal Cancer AJCC v8
Stage IVB Hepatocellular Carcinoma AJCC v8
Stage IVC Colorectal Cancer AJCC v8

Interventions

RADIATION

No Results Yet

NCT04173533 | COMPLETED | PHASE3

326 participants

Randomised Study of Oral Azacitidine vs Placebo Maintenance in AML or MDS Patients After Allo-SCT

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2019-06-14
Completion:: 2026-04-29

Conditions

Acute Myeloid Leukemia
Myelodysplasia

Interventions

DRUG

No Results Yet

NCT04163809 | NOT_YET_RECRUITING | NA

80 participants

The Role of Virtual Reality During Regional Anesthesia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2027-01-01
Completion:: 2028-06-30

Conditions

Anxiety
Pain

Interventions

DEVICE

No Results Yet

NCT04146051 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2019-12-04
Completion:: 2026-01-05

Conditions

Myasthenia Gravis, Generalized

Interventions

DRUG

No Results Yet

NCT04115267 | RECRUITING

3600 participants

Attribution of Toxicities Due to Radiotherapy and Immuno-Biological Therapies

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2019-09-13
Completion:: 2030-09-30

Conditions

Cancer
Radiotherapy Side Effect

Interventions

RADIATION

No Results Yet

NCT04104464 | RECRUITING

200 participants

Patient Reported Outcomes for Vascular Malformations EmbolizatioN (PROVEN)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2019-07-22
Completion:: 2028-07-31

Conditions

Vascular Malformations
VM - Vascular Malformation

No Results Yet