Attribution of Toxicities Due to Radiotherapy and Immuno-Biological Therapies
NCT04115267 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 3600
Last updated 2024-06-28
Summary
Every year, new molecular agents enter the market with more and more patients receiving these treatments, especially in the metastatic setting. These molecular agents could correspond to immunotherapy and modulators of signaling pathways. More than 50% of cancer patients will receive radiation therapy during the course of their illness, including radiotherapy aimed a palliating symptoms secondary to metastatic diseases. Therefore, there will be an increasing number of patients who will be receiving radiotherapy while they are still receiving molecular agents. A better understanding of the interaction of these two treatment modalities is needed.
Conditions
- Cancer
- Radiotherapy Side Effect
Interventions
- RADIATION
-
Radiotherapy
Combined modality
Sponsors & Collaborators
-
Centre hospitalier de l'Université de Montréal (CHUM)
lead OTHER
Principal Investigators
-
Philip Wong, MD · CHUM
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-09-13
- Primary Completion
- 2025-09-30
- Completion
- 2025-09-30
Countries
- Canada
Study Locations
More Related Trials
-
Cardiopulmonary Toxicity of Thoracic Radiotherapy
NCT03978377 ·Status: RECRUITING
-
Early Biomarkers of Tumor Response in High Dose Hypofractionated Radiotherapy Word Package 3 : Immune Response
NCT02439008 ·Status: TERMINATED ·Phase: NA
-
Predictive Modelling for Patient Stratification According to Treatment-related Toxicity and Survival After Chemoradiation for Head and Neck Cancer
NCT02103010 ·Status: COMPLETED
-
Immunotherapy And Palliative Radiotherapy Combined In Patients With Advanced Malignancy
NCT03042156 ·Status: COMPLETED
-
Circulating Immunes Cells, Cytokines and Brain Radiotherapy
NCT05082961 ·Status: RECRUITING ·Phase: NA
-
Detection of Circulating Biomarkers of Immunogenic Cell Death
NCT02921854 ·Status: COMPLETED ·Phase: NA
-
Acupuncture for the Immune System in Radiation Cancer Patients
NCT01422928 ·Status: WITHDRAWN ·Phase: PHASE3
-
Optimising Molecular Radionuclide Therapy
NCT04922801 ·Status: COMPLETED
-
Unusual Toxicity Induced by Radiotherapy
NCT03980977 ·Status: COMPLETED ·Phase: NA
-
SBRT + Immunomodulating Systemic Therapy for Inoperable, Recurrent H&N
NCT03402737 ·Status: TERMINATED ·Phase: NA
-
Hypofractionated Radiotherapy in Breast Cancer
NCT03167359 ·Status: COMPLETED ·Phase: NA
-
Investigation of the Timely-coordinated Therapy of Patients With Metastatic Cancer by Radiotherapy Together With Immune Checkpoint Inhibition
NCT03453892 ·Status: COMPLETED
-
Prospective Study on Factors Predicting Chemo-Radiotherapy Induced Pulmonary and Esophageal Injury
NCT00631839 ·Status: UNKNOWN
-
Radiotherapy in Association With Cetuximab in Patients Treated for an Epidermoid Cancer
NCT01647555 ·Status: COMPLETED
-
Adaptive, Image-guided, Intensity-modulated Radiotherapy for Head and Neck Cancer in the Reduced Volumes of Elective Neck
NCT01287390 ·Status: COMPLETED ·Phase: PHASE2
-
Cancer Patients Treated With Immunotherapy in Intensive Care Unit
NCT03357861 ·Status: COMPLETED
-
Helical Tomotherapy as a Radiotherapy Technique for Treating Pelvic and Abdominal Metastases
NCT00129051 ·Status: COMPLETED ·Phase: PHASE1
-
Stereotactic Ablative Radiotherapy for Oligo-Progressive Disease REfractory to Systemic Therapy in Metastatic Cancer
NCT04989725 ·Status: RECRUITING ·Phase: PHASE2
-
Radiotherapy for Extracranial Oligometastatic Breast Cancer
NCT04646564 ·Status: RECRUITING ·Phase: PHASE3
-
Evaluation of Late Effects and Natural History of Disease in Patients Treated With Radiotherapy
NCT00026650 ·Status: RECRUITING
-
Image-Guided Adaptive Radiotherapy for in Detecting Tumors During Treatment in Patients With Head and Neck Cancer
NCT01843673 ·Status: COMPLETED ·Phase: NA
-
Multimodal Assesment of Acute Cardiac Toxicity Induced by Thoracic Radiotherapy in Cancer Patients
NCT04896242 ·Status: COMPLETED
-
Predictors of Radiation Pneumonitis in Locally Advanced Lung Cancer Treated With Chemoradiation
NCT01580579 ·Status: COMPLETED
-
Radiotherapy Safety for Liver Malignancies Using Post-Treatment Imaging
NCT07346573 ·Status: COMPLETED
-
Palliative Radiotherapy Protocol in Head and Neck Cancer
NCT02460471 ·Status: COMPLETED ·Phase: PHASE2