Clinical Trials

NCT07213791 | RECRUITING | PHASE1

241 participants

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-10-22

Completion:

2028-07-31

Conditions

• Ovarian Neoplasms
• Breast Neoplasms
• Pancreatic Intraductal Neoplasms
• Colorectal Neoplasms
• Esophageal Neoplasms
• Stomach Neoplasms
• Cholangiocarcinoma

Interventions

• DRUG

No Results Yet

NCT07207876 | RECRUITING

110 participants

Study of Ceftriaxone and Benzathine Penicillin G During Pregnancy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2026-02-16

Completion:

2027-01-15

Conditions

• Pregnancy

Interventions

• DRUG

No Results Yet

NCT07204951 | COMPLETED | NA

64 participants

Clinical Safety and Efficacy Study of Water Flosser in Enhancing Oral Health Among Healthy Adults Having Plaque-induced Gingivitis and Dental Plaque Accumulation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-11-13

Completion:

2026-02-14

Conditions

• Plaque Induced Gingivitis

Interventions

• DEVICE
• OTHER

No Results Yet

NCT07202884 | RECRUITING | PHASE3

1000 participants

A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-09-30

Completion:

2028-03-31

Conditions

• Urinary Incontinence,Stress

Interventions

• DRUG

No Results Yet

NCT07201922 | RECRUITING | PHASE3

80 participants

A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-02-10

Completion:

2029-05-14

Conditions

• Familial Pulmonary Fibrosis
• Interstitial Lung Abnormalities
• Interstitial Lung Diseases

Interventions

• DRUG

No Results Yet

NCT07200375 | RECRUITING

300 participants

An Observational Study of Glofitamab in Chinese Adult Participants With 2L Diffuse Large B-Cell Lymphoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2025-09-29

Completion:

2029-09-29

Conditions

• Diffuse Large B-Cell Lymphoma

Interventions

• DRUG

No Results Yet

NCT07199738 | RECRUITING

144 participants

A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2025-09-25

Completion:

2036-12-31

Conditions

• Inflammatory Arthritis
• Primary Total Knee Arthroplasty Due to Degenerative Joint Disease (Primary Diagnosis of Osteoarthritis)
• Post-traumatic Arthritis

Interventions

• DEVICE

No Results Yet

NCT07195916 | RECRUITING | PHASE1

280 participants

A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-01-08

Completion:

2028-08-18

Conditions

• Solid Tumors
• Hematologic Malignancies

Interventions

• DRUG

No Results Yet

NCT07188896 | RECRUITING | PHASE2

120 participants

A Randomized Trial of Fianlimab and Cemiplimab +/- Ipilimumab or Ipilimumab Plus Nivolumab in First-line Advanced Renal Cell Carcinoma (RCC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-04-29

Completion:

2029-11-30

Conditions

• Advanced Renal Cell Carcinoma (aRCC)
• Metastatic Renal Cell Carcinoma ( mRCC)
• Clear Cell Renal Cell Carcinoma (ccRCC)

Interventions

• DRUG

No Results Yet

NCT07186101 | RECRUITING | PHASE2

252 participants

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-11-10

Completion:

2027-05-31

Conditions

• Ulcerative Colitis

Interventions

• DRUG

No Results Yet

NCT07178990 | RECRUITING | NA

50 participants

Mobile Platform for Optimizing Wellness and Engagement in Recovery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-12-08

Completion:

2027-07-01

Conditions

• Opioid Agonist Treatment
• Alcohol Use Disorder
• Opioid Use Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT07174336 | RECRUITING | PHASE3

800 participants

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-12-22

Completion:

2029-05-31

Conditions

• Breast Neoplasms
• Neoplasm Metastasis

Interventions

• DRUG

No Results Yet

NCT07174310 | RECRUITING | PHASE3

900 participants

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-11-24

Completion:

2029-06-30

Conditions

• Parkinson's Disease

Interventions

• DRUG

No Results Yet

NCT07170150 | RECRUITING | PHASE3

800 participants

A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-11-12

Completion:

2028-06-07

Conditions

• Alzheimers Disease

Interventions

• DRUG
• OTHER

No Results Yet

NCT07169851 | RECRUITING | PHASE2

204 participants

A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-11-28

Completion:

2026-12-31

Conditions

• Nausea
• Vomiting
• Drug-Related Side Effects and Adverse Reactions
• Neoplasms

Interventions

• DRUG

No Results Yet

NCT07169578 | RECRUITING | PHASE3

800 participants

A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-09-17

Completion:

2028-06-07

Conditions

• Alzheimers Disease

Interventions

• DRUG
• OTHER

No Results Yet

NCT07168668 | NOT_YET_RECRUITING | PHASE2

90 participants

Partial Immune-boost TACE in unrEseCTable HCC Patients Under Systemic Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-09-15

Completion:

2029-08-14

Conditions

• HCC
• Tace
• Immunotherapy

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT07167004 | RECRUITING | NA

216 participants

The GRoceries Aimed at Increasing Nutrition Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-10-14

Completion:

2027-02-16

Conditions

• Type 2 Diabetes
• Type II Diabetes Mellitus
• Type II Diabetes
• Pre-diabetes
• Pre-diabetic
• Pre-diabetic State
• Type 2 Diabetes Mellitus (T2DM)
• Type 2 Diabetes Mellitus
• Type 2 Diabetes (T2DM)

Interventions

• BEHAVIORAL

No Results Yet

NCT07165756 | TERMINATED

34 participants

"Mon Parcours de Vie" Localized Breast Cancer: Announcement, Support, Information on the Disease and Treatments. Pilot Study to Assess the Value of Written Information Documents.

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2025-09-09

Completion:

2026-04-02

Conditions

• Localized Breast Cancer

No Results Yet

NCT07165028 | RECRUITING | PHASE3

4500 participants

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-10-15

Completion:

2030-08-31

Conditions

• Metabolic Dysfunction-Associated Steatotic Liver Disease

Interventions

• DRUG

No Results Yet

NCT07162623 | COMPLETED | NA

62 participants

Clinical Study to Assess Safety, Efficacy and In-Use Tolerability of Oziva Bioactive Gluta Fizzy Effervescent Tablets on Subjects With Facial Dark Spots Such as Pimple Marks, Sunspots, Age Spots and Uneven Skin Tone

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-09-02

Completion:

2026-04-15

Conditions

• Hyperpigmentation

Interventions

• OTHER

No Results Yet

NCT07161999 | RECRUITING | PHASE2/PHASE3

120 participants

Study of COYA 302 for the Treatment of ALS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-10-01

Completion:

2027-01-31

Conditions

• Amyotrophic Lateral Sclerosis (ALS)

Interventions

• DRUG

No Results Yet

NCT07159204 | ACTIVE_NOT_RECRUITING | PHASE2

61 participants

Polymeric Micellar Paclitaxel-Based Combination Therapy for Advanced Biliary Tract Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-07

Completion:

2026-08-12

Conditions

• Biliary Tract Cancer (BTC)

Interventions

• DRUG

No Results Yet

NCT07156474 | ACTIVE_NOT_RECRUITING

44504 participants

Impact of Intraoperative Blood Pressure Components on Postoperative AKI: A Phenotype-Stratified Analysis

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2025-09-09

Completion:

2026-12-31

Conditions

• Postoperative Acute Kidney Injury
• Intraoperative Hypotension

No Results Yet

NCT07153471 | RECRUITING | PHASE3

800 participants

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-09-15

Completion:

2028-04-30

Conditions

• Osteoarthritis

Interventions

• DRUG

No Results Yet

NCT07144228 | RECRUITING

300 participants

Validation of a Platelet Proteomic Assay for Diagnosing and Monitoring Prostate Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2026-03-11

Completion:

2026-09-30

Conditions

• Prostate Cancer (Diagnosis)

Interventions

• DEVICE

No Results Yet

NCT07144137 | RECRUITING

75 participants

A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2025-07-30

Completion:

2027-03-31

Conditions

• Geographic Atrophy Secondary to Age-related Macular Degeneration

No Results Yet

NCT07142655 | COMPLETED

1500 participants

An Observational Study to Learn More About the Safety of Rivaroxaban in Participants With Peripheral Arterial Disease Who Had Surgery to Improve Blood Flow to Their Legs

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2025-08-12

Completion:

2026-03-09

Conditions

• Peripheral Arterial Disease (PAD)

No Results Yet

NCT07136922 | RECRUITING | PHASE1

20 participants

First in Human Safety and Ease of Use Assessment of 400mg Progesterone Callavid in Women With Luteal Phase Insufficiency

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-04-20

Completion:

2026-08-31

Conditions

• Luteal Phase Insuffiency
• Progesterone Delivery

Interventions

• COMBINATION_PRODUCT
• DRUG

No Results Yet

NCT07129226 | RECRUITING | NA

60 participants

Musculoskeletal Cancers Remote Monitoring and Care

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-02-12

Completion:

2026-11-30

Conditions

• Osteosarcoma
• Metastatic Bone Disease

Interventions

• OTHER

No Results Yet

NCT07127874 | RECRUITING | PHASE1

165 participants

A Study of PHN-012 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-09-23

Completion:

2027-09-30

Conditions

• Colon Cancer
• Pancreatic Cancer
• Lung Cancer (NSCLC)
• Advanced Cancer
• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT07117695 | NOT_YET_RECRUITING | NA

150 participants

Duke Cardiometabolic Prevention Clinic's Impact on High-risk Cardiovascular Patients With Uncontrolled Risk Factors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-09-02

Completion:

2027-09-27

Conditions

• ASCVD
• Hyperlipidemia
• Hypertension

Interventions

• OTHER

No Results Yet

NCT07116694 | COMPLETED | PHASE2

33 participants

Assessment of Acute Psychomotor Agitation Measures Associated With Schizophrenia and Bipolar Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-06-19

Completion:

2025-10-07

Conditions

• Bipolar I Disorder
• Bipolar II Disorder
• Schizophrenia
• Schizoaffective Disorder
• Schizophreniform Disorders
• Psychomotor Agitation

Interventions

• DRUG

No Results Yet

NCT07114601 | RECRUITING | PHASE1

421 participants

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-08-06

Completion:

2030-04-30

Conditions

• Breast Neoplasms
• Colorectal Neoplasms
• Prostate Neoplasm
• Endometrial Neoplasms
• Neoplasm Metastasis
• Stomach Neoplasms
• Esophageal Neoplasms

Interventions

• DRUG
• DIAGNOSTIC_TEST

No Results Yet

NCT07110142 | RECRUITING | NA

40 participants

Tongue Proactive Strengthening Exercise Program Following Partial/Hemi Glossectomy and Reconstruction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-12-10

Completion:

2028-06-30

Conditions

• Oral Cancer
• Head and Neck Cancer

Interventions

• OTHER

No Results Yet

NCT07104565 | RECRUITING | PHASE2

56 participants

Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-12-29

Completion:

2027-09-23

Conditions

• Immune Thrombocytopenia

Interventions

• DRUG

No Results Yet

NCT07102979 | TERMINATED | NA

19 participants

Remedial Mechanism of Simvastatin and Ursodeoxycholic Acid in Liver Cirrhosis: Crosstalk of Bile Secretion, Gut Microbiome, and Host Immune Response

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-01-01

Completion:

2025-12-22

Conditions

• Liver Fibrosis

Interventions

• DRUG

No Results Yet

NCT07101666 | NOT_YET_RECRUITING | PHASE2

20 participants

Total Neoadjuvant Therapy With Short Course Radiation Therapy in Gastric Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-10-31

Completion:

2031-04-30

Conditions

• Gastric Cancer

Interventions

• RADIATION
• DRUG

No Results Yet

NCT07097584 | COMPLETED | NA

180 participants

Effect of Small Double-lumen Tube on the Intubation Time of Thoracoscopic Pulmonectomy in Asian Women

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-07-28

Completion:

2025-12-22

Conditions

• Women
• Asian
• Thoracic Surgery With One-lung Ventilation

Interventions

• DEVICE

No Results Yet

NCT07094256 | RECRUITING | NA

25 participants

Torque Device Evaluation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-08-25

Completion:

2026-12-31

Conditions

• Electrophysiology Study
• Ablation

Interventions

• DEVICE

No Results Yet