An Observational Study of Glofitamab in Chinese Adult Participants With 2L Diffuse Large B-Cell Lymphoma
NCT07200375 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 300
Last updated 2026-05-04
Summary
This study will investigate how well glofitamab-based therapy works and how safe it is in Chinese adult participants with relapsed or refractory diffuse large B-cell lymphoma (R/R DLBCL).
Conditions
- Diffuse Large B-Cell Lymphoma
Interventions
- DRUG
-
Glofitamab
Participants will receive glofitamab as part of a cancer-treatment regimen in a real-world setting. No intervention will be administered by study investigators.
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Clinical Trials · Hoffmann-La Roche
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-09-29
- Primary Completion
- 2029-09-29
- Completion
- 2029-09-29
Countries
- China
Study Locations
More Related Trials
-
The Efficacy and Safety of Glofitamab in Combination With PD-1 Antibody and Lenalidomide in Patients With Relapsed/Refractory Large B-cell Lymphoma (LBCL) With TP53 Aberrations: A Prospective, Multicenter, Phase II Clinical Study
NCT07240194 ·Status: RECRUITING ·Phase: PHASE2
-
Hypofractionation Radiotherapy in Combination With Glofitamab in Relapsed/Refractory Diffuse B-cell Lymphoma With Baseline High Tumor Burden
NCT06867536 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma
NCT05533775 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Glofitamab Combined With CAR-T Therapy in R/R DLBCL
NCT07326371 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Glofitamab Bridging ASCT for Patients With Relapsed or Refractory DLBCL
NCT06682130 ·Status: RECRUITING ·Phase: PHASE2
-
Large Fraction Radiation Therapy Combined With Lenalidomide, and Glofitamab in Refractory Relapsed DLBCL
NCT06651853 ·Status: RECRUITING ·Phase: PHASE2
-
A Study Evaluating the Efficacy, Safety, and Pharmacokinetics of Glofitamab in Combination With Rituximab Plus Ifosfamide, Carboplatin Etoposide Phosphate in Participants With Relapsed/Refractory Transplant or CAR-T Therapy Eligible Diffuse B-Cell Lymphoma
NCT05364424 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase II Study of Glofitamab Plus Polatuzumab-R-CHP for Patients With High-risk Diffuse Large B-cell Lymphoma
NCT05800366 ·Status: RECRUITING ·Phase: PHASE2
-
Glofitamab Plus Polatuzumab Vedotin and Zuberitamab in Patients With Newly Diagnosed Diffuse Large B-cell Lymphoma
NCT07231250 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Study of Glofitamab in Combination With Rituximab or Obinutuzumab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP), or Polatuzumab Vedotin Plus Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone (CHP) in Participants With Non-Hodgkin Lymphomas or With DLBCL
NCT03467373 ·Status: COMPLETED ·Phase: PHASE1
-
Clinical Study With Blinatumomab in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL)
NCT01741792 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of GLB-002 in Patients With Relapsed or Refractory Non-Hodgkin Lymphomas
NCT06219356 ·Status: RECRUITING ·Phase: PHASE1
-
A Phase III Study Evaluating Glofitamab in Combination With Gemcitabine + Oxaliplatin vs Rituximab in Combination With Gemcitabine + Oxaliplatin in Participants With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
NCT04408638 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
An Observational Study of MabThera/Rituxan (Rituximab) Plus Chemotherapy As First-Line Treatment in Patients With Diffuse Large B-Cell Lymphoma or Follicular Lymphoma
NCT01340443 ·Status: COMPLETED
-
Glofitamab for Consolidation After First-line Treatment of High-risk Large B-cell Lymphoma
NCT06956092 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
A Study of Glofitamab-based Treatment in People With Diffuse Large B-cell Lymphoma
NCT06765317 ·Status: RECRUITING ·Phase: PHASE2
-
Evaluate the Safety and Efficacy of Tafasitamab Combined With Lenalidomide in Patients With Relapsed or Refractory DLBCL
NCT05552937 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Learn About the Effects of Two Study Medicines (Maplirpacept [PF-07901801] And Glofitamab) When Given Together In People With Relapsed Or Refractory Diffuse Large B Cell Lymphoma.
NCT05896163 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Lenalidomide Plus ICE in the Treatment of Refractory and Relapsed DLBCL
NCT03367143 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of Rocbrutinib in Participants With Relapse or Refractory Non-GCB Diffuse Large B-Cell Lymphoma
NCT07189065 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RO7443904 in Combination With Glofitamab in Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma
NCT05219513 ·Status: TERMINATED ·Phase: PHASE1
-
Glofitamab in Relapsed or Refractory Diffuse Large B-cell Lymphoma After CD19 Chimeric Antigen Receptor T-cell Therapy
NCT06552572 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study to Evaluate the Safety and Efficacy of Glofitamab in Combination With Rituximab (R) Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) in Circulating Tumor (ct)DNA High-Risk Patients With Untreated Diffuse Large B-Cell Lymphoma
NCT04980222 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
R-CDOP Combined With Intrathecal Methotrexate for DLBCL Patients With High-risk of CNS Relapse
NCT05257018 ·Status: RECRUITING ·Phase: PHASE2
-
Lenalidomide Combined With G-CHOP in the Treatment of Newly Diagnosed DLBCL With FL
NCT06151080 ·Status: RECRUITING ·Phase: PHASE2