A Study of PHN-012 in Patients With Advanced Solid Tumors
NCT07127874 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 165
Last updated 2026-04-17
Summary
This first-in-human study will evaluate safety, tolerability, anti-tumor activity, immunogenicity, pharmacokinetics and pharmacodynamics of PHN-012, a novel antibody-drug conjugate (ADC), in patients with advanced solid tumors.
Conditions
- Colon Cancer
- Pancreatic Cancer
- Lung Cancer (NSCLC)
- Advanced Cancer
- Advanced Solid Tumors
Interventions
- DRUG
-
PHN-012
PHN-012 is an ADC
Sponsors & Collaborators
-
Pheon Therapeutics
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-09-23
- Primary Completion
- 2027-09-30
- Completion
- 2028-05-31
- FDA Drug
- Yes
Countries
- United States
- Spain
Study Locations
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