Clinical Trials

NCT04994808 | TERMINATED | PHASE2

23 participants

Treosulfan-Based Versus Clofarabine-Based Conditioning Before Donor Hematopoietic Stem Cell Transplant for the Treatment of Myelodysplastic Syndromes or Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-08-11

Completion:

2026-01-22

Conditions

• Acute Myeloid Leukemia
• Myelodysplastic Syndrome

Interventions

• DRUG
• PROCEDURE
• RADIATION

No Results Yet

NCT04969094 | ACTIVE_NOT_RECRUITING | NA

81 participants

Reducing Fall Risk With NMES

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-01-04

Completion:

2026-12-20

Conditions

• Falls

Interventions

• OTHER

No Results Yet

NCT04967365 | COMPLETED

755 participants

Post-Intensive Care Syndrome - Pediatrics (PICS-p): Longitudinal Cohort Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2021-07-27

Completion:

2026-01-31

Conditions

• Critical Illness
• Post Intensive Care Unit Syndrome

No Results Yet

NCT04930744 | COMPLETED | PHASE2

112 participants

Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-03-04

Completion:

2025-04-29

Conditions

• Tuberculosis
• Pulmonary Tuberculosis
• HIV Coinfection

Interventions

• DRUG

Results Available

NCT04876248 | ACTIVE_NOT_RECRUITING | PHASE2

4 participants

Belantamab Mafodotin and Lenalidomide for the Treatment of Multiple Myeloma in Patients With Minimal Residual Disease Positive After Stem Cell Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-19

Completion:

2026-12-01

Conditions

• Plasma Cell Myeloma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04862325 | COMPLETED | NA

158 participants

SOPHIE Trial: Surgery in Ovarian Cancer With PreHabilitation In ERAS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-04-20

Completion:

2026-04-28

Conditions

• Advanced Ovarian Cancer

Interventions

• OTHER

No Results Yet

NCT04826237 | TERMINATED | PHASE4

3 participants

Oral Statins and Protection From Hearing Loss

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-02-09

Completion:

2025-10-30

Conditions

• Sudden Sensorineural Hearing Loss

Interventions

• DRUG

No Results Yet

NCT04804553 | RECRUITING | PHASE3

60 participants

Apremilast Pediatric Study in Children With Active Juvenile Psoriatic Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-03-17

Completion:

2028-03-21

Conditions

• Active Juvenile Psoriatic Arthritis

Interventions

• DRUG

No Results Yet

NCT04766190 | ACTIVE_NOT_RECRUITING | NA

254 participants

DISCO: A Patient Intervention to Reduce the Financial Burden of Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-02-10

Completion:

2027-08-31

Conditions

• Financial Toxicity
• Cancer
• Question Prompt List
• Breast Cancer
• Prostate Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT04743791 | RECRUITING | PHASE4

30 participants

Measuring the Effect of Dupilumab Treatment on Mucociliary Clearance (MCC) in Subjects With Moderate to Severe Asthma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-10-17

Completion:

2027-12-31

Conditions

• Asthma

Interventions

• DRUG
• OTHER

No Results Yet

NCT04730869 | COMPLETED | NA

18 participants

Metabolic Therapy Program In Conjunction With Standard Treatment For Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-05-26

Completion:

2025-02-18

Conditions

• Glioblastoma

Interventions

• OTHER

No Results Yet

NCT04717349 | RECRUITING

11000 participants

Data Collection Study of Pediatric and Adolescent Gynecology Conditions

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2021-04-21

Completion:

2039-12-02

Conditions

• Disorders of Sex Development (DSD)
• Pediatric and Adolescent Cancers of the Genital Tract
• Reproductive Endocrine Conditions in Puberty
• Structural Gynecologic Conditions Including Vulvar and Vaginal Conditions

No Results Yet

NCT04715191 | RECRUITING | PHASE1

24 participants

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-05-24

Completion:

2027-08-01

Conditions

• Liver Cancer
• Rhabdomyosarcoma
• Malignant Rhabdoid Tumor
• Liposarcoma
• Wilms Tumor
• Yolk Sac Tumor

Interventions

• GENETIC

No Results Yet

NCT04640142 | ACTIVE_NOT_RECRUITING | PHASE3

50 participants

Study to Evaluate the Pharmacokinetics, Efficacy, Tolerability, and Safety of Subcutaneous Human Immunoglobulin (Newnorm) in Patients With Primary Immunodeficiency Diseases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-08-04

Completion:

2026-09-30

Conditions

• Primary Immune Deficiency

Interventions

• BIOLOGICAL

No Results Yet

NCT04628026 | RECRUITING | PHASE3

650 participants

Phase III Study of Induction and Consolidation Chemotherapy With Venetoclax in Patients With Newly Diagnosed AML or MDS-EB-2

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-09-13

Completion:

2029-03-31

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG
• COMBINATION_PRODUCT
• OTHER

No Results Yet

NCT04599504 | COMPLETED | PHASE2/PHASE3

16 participants

Pharmacological and Behavioral Treatment After Bariatric Surgery: Medication Change for Non-Responders (Stage 2b)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-01-02

Completion:

2026-06-04

Conditions

• Loss-of-control Eating
• Obesity/Overweight

Interventions

• DRUG
• OTHER

Results Available

NCT04527549 | TERMINATED | PHASE2

5 participants

Testing Dabrafenib and Trametinib With or Without Hydroxychloroquine in Stage IIIC or IV BRAF V600E/K Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-06-01

Completion:

2024-01-08

Conditions

• Clinical Stage IV Cutaneous Melanoma AJCC v8
• Locally Advanced Melanoma
• Pathologic Stage IIIC Cutaneous Melanoma AJCC v8
• Pathologic Stage IV Cutaneous Melanoma AJCC v8
• Unresectable Melanoma

Interventions

• DRUG

Results Available

NCT04469959 | COMPLETED | PHASE2

79 participants

Dopaminergic Dysfunction in Late-Life Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-02-15

Completion:

2026-04-29

Conditions

• Late Life Depression
• Cognitive Decline
• Depressive Disorder, Treatment-Resistant
• Levodopa
• Gait Impairment

Interventions

• DRUG

No Results Yet

NCT04469686 | COMPLETED | PHASE3

200 participants

Phase 3 Study to Evaluate the Safety and Efficacy of Hydrocortisone Acetate Suppositories

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-12-10

Completion:

2024-09-19

Conditions

• Ulcerative Proctitis

Interventions

• COMBINATION_PRODUCT

Results Available

NCT04455048 | COMPLETED | NA

84 participants

The Effectiveness of Manipulation Treatment in Cervical Region

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-02-02

Completion:

2023-10-16

Conditions

• Neck Pain

Interventions

• OTHER

No Results Yet

NCT04450459 | COMPLETED

121 participants

Impact of Spiroergometer Parameters as Diagnostic Marker of Cardiac Ischemia in Pts. With Stable Angina Compared to FFR.

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2019-01-02

Completion:

2025-08-25

Conditions

• Stable Angina

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04386967 | COMPLETED | PHASE1/PHASE2

44 participants

OH2 Injection in Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2018-11-22

Completion:

2026-06-02

Conditions

• Solid Tumor
• Melanoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04352569 | COMPLETED | NA

25 participants

Efficacy of tDCS in the Treatment of Resistant Auditory Hallucinations in Schizophrenia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2016-05-03

Completion:

2025-03-31

Conditions

• Schizophrenia
• Hallucinations
• Refractory Schizophrenia

Interventions

• DEVICE

No Results Yet

NCT04332341 | RECRUITING | EARLY_PHASE1

20 participants

Study of Nicotinamide Riboside Supplementation in Allogeneic Hematopoietic Cell Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-05-19

Completion:

2026-09-30

Conditions

• Allogeneic Hematopoietic Cell Transplantation

Interventions

• DRUG

No Results Yet

NCT04298723 | RECRUITING | NA

530 participants

Comparison of LAA-Closure vs Oral Anticoagulation in Patients With NVAF and Status Post Intracranial Bleeding.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-06-16

Completion:

2029-06-30

Conditions

• Intracranial Hemorrhages
• Atrial Fibrillation (AF)
• Atrial Flutter

Interventions

• DEVICE

No Results Yet

NCT04289324 | COMPLETED | NA

36 participants

Open Lung Maneuvers During High Frequency Oscillatory Ventilation in Preterm Infants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-02-25

Completion:

2025-08-31

Conditions

• High Frequency Oscillation Ventilation
• Extreme Prematurity
• Lung Injury, Acute

Interventions

• PROCEDURE

No Results Yet

NCT04246788 | COMPLETED | NA

40 participants

Intensive Robotic Rehabilitation in Children With Hemiparesia Using GEOSYSTEM

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-07-17

Completion:

2021-11-24

Conditions

• Infantile Hemiplegia

Interventions

• OTHER

No Results Yet

NCT04224987 | COMPLETED | PHASE4

864493 participants

Azithromycin for Child Survival in Niger: Mortality and Resistance Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-11-24

Completion:

2024-07-31

Conditions

• Mortality
• Resistance Bacterial
• Child, Only

Interventions

• DRUG
• OTHER

Results Available

NCT04221542 | RECRUITING | PHASE1

479 participants

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-03-04

Completion:

2030-03-22

Conditions

• Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT04221438 | TERMINATED | PHASE2

3 participants

Testing Treatment With Encorafenib and Binimetinib Before Surgery for Melanoma With Lymph Node Involvement

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-09-22

Completion:

2024-06-10

Conditions

• Melanoma of Unknown Primary
• Metastatic Malignant Neoplasm in Lymph Node
• Pathologic Stage IIIB Cutaneous Melanoma AJCC v8
• Pathologic Stage IIIC Cutaneous Melanoma AJCC v8
• Pathologic Stage IIID Cutaneous Melanoma AJCC v8
• Recurrent Cutaneous Melanoma

Interventions

• DRUG
• PROCEDURE
• OTHER

Results Available

NCT04218617 | RECRUITING | PHASE2

130 participants

Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-02-07

Completion:

2026-10-31

Conditions

• Spine Metastases
• Spine Stereotactic Radiosurgery (sSRS)

Interventions

• DEVICE
• OTHER
• RADIATION

No Results Yet

NCT04193878 | TERMINATED | PHASE3

465 participants

ARrest RESpiraTory Failure From PNEUMONIA

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-06-01

Completion:

2025-07-22

Conditions

• Pneumonia
• Hypoxemia
• Acute Respiratory Failure
• COVID-19 Pneumonia

Interventions

• DRUG

Results Available

NCT04192591 | ACTIVE_NOT_RECRUITING | NA

166 participants

A 5-year Superion™ IDS Clinical Outcomes Post-Approval Evaluation (SCOPE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-01-30

Completion:

2038-02-28

Conditions

• Lumbar Spinal Stenosis

Interventions

• DEVICE

No Results Yet

NCT04179643 | COMPLETED | PHASE1

11 participants

AB-1002 in Patients With Class III Heart Failure

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-11-20

Completion:

2024-08-20

Conditions

• Congestive Heart Failure
• Heart Failure
• Heart Disease, Ischemic
• Cardiovascular Diseases
• Heart Failure, Systolic
• Heart Failure，Congestive
• Heart Arrhythmia
• Heart Failure, Diastolic
• Heart; Complications

Interventions

• BIOLOGICAL

No Results Yet

NCT04165694 | COMPLETED | NA

54 participants

Single Anastomosis Duodenal Ileal Bypass (SADI) for Sleeve Revision

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-10-15

Completion:

2025-05-01

Conditions

• Bariatric Surgery Candidate
• Severe Obesity

Interventions

• PROCEDURE

No Results Yet

NCT04151940 | RECRUITING | NA

80 participants

PET/CT Changes During Chemoimmunotherapy and Radiation Therapy in Patients With Stage IV Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-09-26

Completion:

2027-11-30

Conditions

• Metastatic Lung Non-Small Cell Carcinoma
• Recurrent Lung Non-Small Cell Carcinoma
• Stage IV Lung Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• RADIATION

No Results Yet

NCT04150939 | ACTIVE_NOT_RECRUITING | NA

15 participants

Cryoablation for the Treatment of Metastatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-12-23

Completion:

2028-08-31

Conditions

• Metastatic Malignant Neoplasm

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04122976 | ACTIVE_NOT_RECRUITING

805 participants

A Study in Which Non-metastatic Castration-resistant Prostate Cancer (nmCRPC) Patients for Whom a Decision to Treat With Darolutamide Has Been Made Before Enrollment Are Observed and Certain Outcomes Are Described

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2020-01-30

Completion:

2026-07-20

Conditions

• Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT04114903 | COMPLETED

233 participants

Exploring the Anti-inflammatory Properties of Cannabis and Their Relevance to Insulin Sensitivity

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2019-11-08

Completion:

2024-12-01

Conditions

• Type 2 Diabetes
• Obesity
• Cannabis Use
• Insulin Sensitivity

Interventions

• OTHER

Results Available

NCT04106713 | RECRUITING | NA

250 participants

Understanding the Person, Exploring Change Across Psychotherapies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-10-04

Completion:

2026-09-30

Conditions

• Depression
• Anxiety Disorders

Interventions

• BEHAVIORAL

No Results Yet