Cryoablation for the Treatment of Metastatic Cancer
NCT04150939 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15
Last updated 2026-08-06
Summary
This interventional trial studies the effectiveness of adding cryoablation treatment in patients who are receiving standard of care immunotherapy to treat cancer that is has spread to other parts of the body (metastatic). Cryoablation uses a probe that freezes the tissue around the tumor to try to kill the cancer cells. Using cryoablation to treat cancerous lesions may help to kill the cancer cells.
Conditions
- Metastatic Malignant Neoplasm
Interventions
- PROCEDURE
-
Core Biopsy
Undergo core biospy
- PROCEDURE
-
Cryosurgery
Undergo cryoablation
- DRUG
-
Immunotherapeutic Agent
Receive standard of care immunotherapy
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
M.D. Anderson Cancer Center
lead OTHER
Principal Investigators
-
Alda L Tam · M.D. Anderson Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-12-23
- Primary Completion
- 2028-08-31
- Completion
- 2028-08-31
- FDA Device
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Therapeutic Autologous Lymphocytes, Cyclophosphamide, and Aldesleukin in Treating Patients With Metastatic Melanoma
NCT01106235 ·Status: TERMINATED ·Phase: PHASE1
-
Aerosolized Aldesleukin in Treating Patients With Lung Metastases
NCT01590069 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Immunotherapy in Treating Patients With Metastatic Breast Cancer
NCT00003432 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Vaccine and Chemotherapy for Previously Untreated Metastatic Breast Cancer
NCT00048893 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00019214 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Use of IL-15 After Chemotherapy and Lymphocyte Transfer in Metastatic Melanoma
NCT01369888 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Vaccine Therapy in Treating Patients With Metastatic or Recurrent Cancer
NCT00017537 ·Status: WITHDRAWN ·Phase: PHASE1
-
Lymphocyte Re-infusion During Immune Suppression to Treat Metastatic Melanoma
NCT00001832 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Metastatic Cancer
NCT00021164 ·Status: COMPLETED ·Phase: PHASE2
-
High Dose I-131 Metaiodobenzylguanidine(MIBG) for Metastatic Neuroendocrine Tumors
NCT00037869 ·Status: COMPLETED ·Phase: PHASE3
-
Interleukin-7 in Treating Patients With Refractory Solid Tumors
NCT00062049 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy in Treating Patients With Metastatic Melanoma
NCT00019994 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 2 Trial for Patients With Metastatic Solid Cancer
NCT04713371 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Radiation, Chemotherapy, Vaccine and Anti-MART-1 and Anti-gp100 Cells for Patients With Metastatic Melanoma
NCT00923195 ·Status: COMPLETED ·Phase: PHASE2
-
Monoclonal Antibody Therapy and Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00058279 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Melanoma
NCT01993719 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer
NCT00019591 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
IMC-A12 in Treating Patients With Advanced Liver Cancer
NCT00639509 ·Status: COMPLETED ·Phase: PHASE2
-
CD8+ Antigen-Specific T Cells, Cyclophosphamide, Aldesleukin, and Ipilimumab in Treating Patients With Metastatic Melanoma
NCT02027935 ·Status: COMPLETED ·Phase: PHASE2
-
Interleukin-21 in Treating Patients With Metastatic or Recurrent Malignant Melanoma
NCT00514085 ·Status: COMPLETED ·Phase: PHASE2
-
Interleukin-2 Plus Activated White Blood Cells in Treating Patients With Cancer That Has Not Responded to Chemotherapy or Radiation Therapy
NCT00019357 ·Status: COMPLETED ·Phase: PHASE1
-
High-Dose Interferon Alfa and Interleukin-2 in Treating Patients With Metastatic Kidney Cancer or Melanoma
NCT00003091 ·Status: COMPLETED ·Phase: PHASE2
-
T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-A*01 Positive
NCT02153905 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors
NCT04119024 ·Status: RECRUITING ·Phase: PHASE1
-
Gene Therapy in Treating Patients With Metastatic Melanoma
NCT00005943 ·Status: COMPLETED ·Phase: PHASE1