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Open Lung Maneuvers During High Frequency Oscillatory Ventilation in Preterm Infants

NCT04289324 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2024-11-20

No results posted yet for this study

Summary

To assess whether stepwise oxygenation-guided lung recruitment at regular intervals reduces the oxygen saturation index (OSI = Mean Airway Pressure × Fraction of inspired Oxygen × 100 / peripheral Oxygen Saturation, OSI = MAPxFiO2x100/SpO2) averaged over high frequency oscillation ventilation (HFOV) time in extremely preterm infants.

Conditions

  • High Frequency Oscillation Ventilation
  • Extreme Prematurity
  • Lung Injury, Acute

Interventions

PROCEDURE

regular lung recruitment

stepwise oxygenation-guided lung recruitment at regular (twelve hours) intervals during high frequency oscillation ventilation

Sponsors & Collaborators

  • Medical University of Vienna

    lead OTHER

Principal Investigators

  • Tobias Werther · Medical University of Vienna

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Max Age
8 Weeks
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-02-25
Primary Completion
2025-08-31
Completion
2025-12-31

Countries

  • Austria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04289324 on ClinicalTrials.gov