Clinical Trials

NCT04285671 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

30 participants

Necitumumab and Trastuzumab in Combination With Osimertinib for the Treatment of Refractory Epidermal Growth Factor Receptor (EGFR)-Mutated Stage IV Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2021-01-29

Completion:

2026-12-02

Conditions

• Metastatic Lung Non-Small Cell Carcinoma
• Refractory Lung Non-Small Cell Carcinoma
• Stage IV Lung Cancer American Joint Committee on Cancer (AJCC) v8
• Stage IVA Lung Cancer AJCC v8
• Stage IVB Lung Cancer AJCC v8

Interventions

• BIOLOGICAL
• DRUG
• OTHER

No Results Yet

NCT04230109 | RECRUITING | PHASE2

239 participants

Sacituzumab Govitecan In TNBC

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2020-07-14

Completion:

2028-10-31

Conditions

• Invasive Breast Cancer
• Triple Negative Breast Cancer
• ER-Negative Breast Cancer
• PR-Negative Breast Cancer
• HER2-negative Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04190251 | COMPLETED | NA

73 participants

PANDIA IRIS: Patients With Diabetes and Kidney Failure, an Interdisciplinary Medication Adherence Support Program

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2016-04-14

Completion:

2022-12-20

Conditions

• Diabetes Mellitus, Type 2
• Renal Insufficiency, Chronic

Interventions

• OTHER

No Results Yet

NCT04188899 | NOT_YET_RECRUITING

150 participants

Point-of-care Ultrasound in the Assessment of Snake Bite

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-17

Start Date:

2026-08-31

Completion:

2029-08-31

Conditions

• Rattlesnake Bite (Diagnosis)

No Results Yet

NCT04122456 | RECRUITING | NA

48 participants

DNA Repair Activity in the Skin of Day and Night Shift Workers

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2022-12-07

Completion:

2027-12-31

Conditions

• Skin Cancer

Interventions

• RADIATION
• OTHER

No Results Yet

NCT04115631 | ACTIVE_NOT_RECRUITING | PHASE2

360 participants

A Comparison of Three Chemotherapy Regimens for the Treatment of Patients With Newly Diagnosed Mantle Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2019-12-13

Completion:

2026-12-31

Conditions

• Liver Lymphoma
• Mantle Cell Lymphoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04090411 | COMPLETED | PHASE2

246 participants

A Study to Evaluate the Efficacy and Safety of PF-06480605 in Adults With Moderate to Severe Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2019-12-19

Completion:

2022-10-25

Conditions

• Moderate to Severe Ulcerative Colitis

Interventions

• DRUG
• OTHER

Results Available

NCT04047342 | COMPLETED

824 participants

Assessing the Impact of myHealth Rewards New Hire Enrollment Emails

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-17

Start Date:

2019-07-16

Completion:

2019-12-20

Conditions

• Health Promotion
• Wellness Programs

Interventions

• BEHAVIORAL

Results Available

NCT03950427 | COMPLETED | PHASE4

108 participants

PARQuit Smoking Cessation Intervention for Adults With Serious Mental Illness

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2019-07-08

Completion:

2025-07-30

Conditions

• Smoking Cessation
• Smoking, Tobacco
• Mental Illness
• Tobacco Use Disorder

Interventions

• BEHAVIORAL
• DRUG

Results Available

NCT03938324 | COMPLETED | NA

222 participants

Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2019-10-29

Completion:

2024-06-19

Conditions

• Sickle Cell Disease
• Chronic Kidney Diseases
• Systemic Lupus Erythematosus
• Childhood Cancer
• Inflammatory Bowel Diseases
• Stem Cell Transplant
• Organ Transplant
• Diabetes Mellitus, Type 1
• Cystic Fibrosis

Interventions

• BEHAVIORAL

Results Available

NCT03935906 | COMPLETED | NA

1410 participants

Reaching mEthadone Users Attending Community pHarmacies With HCV

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2019-10-08

Completion:

2021-01-14

Conditions

• Hepatitis C

Interventions

• OTHER

Results Available

NCT03906253 | RECRUITING | NA

72 participants

Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2018-01-10

Completion:

2028-12-31

Conditions

• Actinic Keratoses
• Aging
• Non-Melanoma Skin Cancer

Interventions

• DEVICE

No Results Yet

NCT03841097 | ACTIVE_NOT_RECRUITING | PHASE4

60 participants

Pulse Wave Velocity, Tacrolimus Time in Therapeutic Range and CV in African American Kidney Transplants

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2019-11-11

Completion:

2026-12-31

Conditions

• Kidney Transplant; Complications

Interventions

• DRUG

No Results Yet

NCT03827941 | RECRUITING | NA

40 participants

Auricular Transcutaneous Electrical Nerve Stimulation Treatment of Autism

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2022-11-01

Completion:

2027-09-28

Conditions

• Autism Spectrum Disorder

Interventions

• OTHER

No Results Yet

NCT03804255 | WITHDRAWN

0 participants

Assessment of Current Biomarker Testing Practices for Common Solid Cancers in Precision Oncology in the Community Setting

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-17

Start Date:

2019-01-08

Completion:

2020-05-29

Conditions

• Breast Carcinoma
• Colorectal Carcinoma
• Community Practice
• Lung Carcinoma
• Melanoma
• Solid Neoplasm

Interventions

• OTHER

No Results Yet

NCT03732677 | ACTIVE_NOT_RECRUITING | PHASE3

1063 participants

Durvalumab+ Gemcitabine/Cisplatin (Neoadjuvant Treatment) and Durvalumab (Adjuvant Treatment) in Patients With MIBC

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2018-11-16

Completion:

2024-04-29

Conditions

• Muscle Invasive Bladder Cancer

Interventions

• DRUG

Results Available

NCT03718260 | COMPLETED | NA

9684 participants

PSMA-PET Registry for Recurrent Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2018-09-27

Completion:

2026-06-15

Conditions

• Recurrent Prostate Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03697148 | ACTIVE_NOT_RECRUITING | NA

852 participants

Multiparametric MRI in Evaluating Cancer Stage and Helping Treatment Planning in Patients With Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2019-02-11

Completion:

2026-12-31

Conditions

• Prostate Carcinoma

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03516279 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2019-06-26

Completion:

2028-08-31

Conditions

• Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
• Minimal Residual Disease

Interventions

• DRUG
• OTHER
• BIOLOGICAL

No Results Yet

NCT03510442 | RECRUITING

2000 participants

Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related Conditions

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-17

Start Date:

2018-05-21

Completion:

2050-01-01

Conditions

• Still's Disease, Adult-Onset
• Systemic Inflammation
• Arthritis
• Autoinflammatory Syndrome

No Results Yet

NCT03504163 | ACTIVE_NOT_RECRUITING | PHASE2

45 participants

Pembrolizumab (MK-3475) and Bacillus Calmette-Guérin (BCG) as First-Line Treatment for High-Risk T1 Non-Muscle-Invasive Bladder Cancer (NMIBC) and High-Grade Non-Muscle-Invasive Upper Tract Urothelial Carcinoma (NMI-UTUC)]

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2018-06-27

Completion:

2027-04-30

Conditions

• Bladder Cancer

Interventions

• DRUG

No Results Yet

NCT03480360 | COMPLETED | PHASE3

21 participants

Haploidentical Allogeneic Peripheral Blood Transplantation: Examining Checkpoint Immune Regulators' Expression

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2018-03-28

Completion:

2025-02-14

Conditions

• Acute Myeloid Leukemia
• Chronic Lymphocytic Leukemia
• Chronic Myeloid Leukemia
• Myelodysplasia
• Myeloproliferative Disorder
• Myelofibrosis
• Lymphoma
• Lymphoma, Non-Hodgkin
• Plasma Cell Disorder

Interventions

• DRUG
• RADIATION
• PROCEDURE

Results Available

NCT03427138 | TERMINATED | NA

89 participants

Training Early Social Language in Autism

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2016-07-01

Completion:

2022-08-31

Conditions

• Autism Spectrum Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT03423628 | ACTIVE_NOT_RECRUITING | PHASE1

159 participants

A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2018-04-02

Completion:

2026-09-03

Conditions

• Recurrent Glioblastoma Multiforme
• Primary Glioblastoma Multiforme
• Brain Neoplasms, Malignant
• Leptomeningeal Disease (LMD)

Interventions

• RADIATION
• DRUG

No Results Yet

NCT03383302 | COMPLETED | PHASE1/PHASE2

36 participants

SBRT With Immunotherapy in Early Stage Non-small Cell Lung Cancer: Tolerability and Lung Effects

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2018-02-08

Completion:

2024-08-12

Conditions

• Non-small Cell Lung Cancer Stage II
• Non-small Cell Lung Cancer Stage I

Interventions

• RADIATION
• DRUG

Results Available

NCT03314688 | COMPLETED | NA

173 participants

Lifestyle, Exercise, and Nutrition Study Early After Diagnosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2018-01-02

Completion:

2023-03-24

Conditions

• Breast Neoplasms

Interventions

• BEHAVIORAL

Results Available

NCT03267433 | ACTIVE_NOT_RECRUITING | PHASE3

689 participants

Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2017-11-27

Completion:

2027-01-31

Conditions

• Mantle Cell Lymphoma

Interventions

• PROCEDURE
• BIOLOGICAL

No Results Yet

NCT03230747 | ACTIVE_NOT_RECRUITING | NA

72 participants

SAPIEN M3 EFS: Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral Regurgitation

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2017-09-14

Completion:

2021-06-16

Conditions

• Mitral Regurgitation
• Mitral Disease

Interventions

• DEVICE

No Results Yet

NCT03115333 | ACTIVE_NOT_RECRUITING | NA

146 participants

DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2017-07-25

Completion:

2025-12-31

Conditions

• Gliosarcoma
• Recurrent Glioblastoma

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03100279 | COMPLETED | NA

247 participants

Process and Outcomes in CBT for Anxious and Depressed Youth

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2005-07-01

Completion:

2020-01-31

Conditions

• Anxiety Disorders
• Depression

Interventions

• BEHAVIORAL

No Results Yet

NCT03077360 | COMPLETED | NA

62 participants

Skeletal Muscle Diacylglycerol and Sphingolipids - Impact of Localization and Species on Insulin Resistance in Humans

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2017-02-01

Completion:

2020-11-19

Conditions

• Diabetes Mellitus, Type 2
• Pre-diabetes
• Obesity

Interventions

• BEHAVIORAL

Results Available

NCT03069378 | ACTIVE_NOT_RECRUITING | PHASE2

41 participants

A Study of Talimogene Laherparepvec (T-VEC) in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2017-03-03

Completion:

2025-07-22

Conditions

• Sarcoma
• Epithelioid Sarcoma
• Cutaneous Angiosarcoma

Interventions

• DRUG

Results Available

NCT02993796 | RECRUITING

60 participants

Krabbe Disease Global Patient Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-17

Start Date:

2014-09-30

Completion:

2026-09-30

Conditions

• Krabbe Disease

No Results Yet

NCT02967276 | TERMINATED | PHASE2

28 participants

Clinical Activity of Metformin With High-dose of Dexamethasone in Relapse Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2017-01-31

Completion:

2019-10-31

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT02902757 | COMPLETED | NA

7 participants

FDG PET/CT in Monitoring Very Early Therapy Response in Patients With Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2015-08-25

Completion:

2025-01-29

Conditions

• Glioblastoma

Interventions

• PROCEDURE
• RADIATION

No Results Yet

NCT02740634 | RECRUITING | NA

60 participants

Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2016-05-31

Completion:

2027-03-31

Conditions

• Atypical Alzheimer's Disease
• Logopenic Progressive Aphasia (LPA)
• Posterior Cortical Atrophy (PCA)
• Alzheimer Disease
• Alzheimer Disease, Early Onset
• Amnestic Disorder
• Amnestic Symptoms
• Amnestic Mild Cognitive Disorder

Interventions

• DRUG

No Results Yet

NCT02721732 | ACTIVE_NOT_RECRUITING | PHASE2

157 participants

Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2016-08-15

Completion:

2028-12-31

Conditions

• Advanced Malignant Solid Neoplasm
• Carcinoma of Unknown Primary
• Metastatic Adrenal Gland Pheochromocytoma
• Metastatic Kidney Medullary Carcinoma
• Metastatic Malignant Germ Cell Tumor
• Metastatic Malignant Solid Neoplasm
• Metastatic Paraganglioma
• Metastatic Penile Carcinoma
• Metastatic Skin Squamous Cell Carcinoma
• Small Cell Carcinoma
• Stage III Adrenal Cortex Carcinoma AJCC v7
• Stage IV Adrenal Cortex Carcinoma AJCC v7
• Stage IV Penile Cancer AJCC v7
• Stage IV Renal Cell Cancer AJCC v7
• Unresectable Adrenal Gland Pheochromocytoma
• Unresectable Paraganglioma
• Unresectable Skin Squamous Cell Carcinoma
• Unresectable Solid Neoplasm
• Vascular Neoplasm

Interventions

• OTHER
• BIOLOGICAL

Results Available

NCT02708836 | RECRUITING | NA

130 participants

Limiting Emergence Phenomena After General Anesthesia With Combined LMA and ETT Airway Management Technique

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2020-01-01

Completion:

2028-06-01

Conditions

• Limit Emergence Phenomena After General Anesthesia

Interventions

• PROCEDURE
• DEVICE

No Results Yet

NCT02694783 | COMPLETED | EARLY_PHASE1

60 participants

Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy With Ex Vivo Generated Polyomavirus-Specific T-Cells

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2016-03-28

Completion:

2019-12-13

Conditions

• Progressive Multifocal Leukoencephalopathy

Interventions

• BIOLOGICAL

No Results Yet

NCT02656511 | ACTIVE_NOT_RECRUITING | PHASE4

74 participants

Immediate Initiation of Antiretroviral Therapy During "Hyperacute" HIV Infection

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-17

Start Date:

2015-12-31

Completion:

2027-05-31

Conditions

• HIV

Interventions

• DRUG

No Results Yet