MedTrace Logo

DNA Repair Activity in the Skin of Day and Night Shift Workers

NCT04122456 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 48

Last updated 2025-02-06

No results posted yet for this study

Summary

The purpose of this study is to test how the skin of night shift workers responds to artificial sunlight (ultraviolet B radiation; UVB) at two different times of the day in comparison to normal day shift workers. After the skin biopsies are obtained, they will be brought to the laboratory to be exposed to UVB radiation and to measure UVB responses.

Conditions

Interventions

RADIATION

Ultraviolet B Radiation

One skin punch biopsy will be taken to the laboratory for exposure to ultraviolet B radiation. After 1-hour incubation, the biopsies will be bisected in half.

OTHER

No Ultraviolet B Radiation

One skin punch biopsy will be taken to the laboratory and will be kept as a non-irradiated control.

Sponsors & Collaborators

  • Wright State University

    lead OTHER

Principal Investigators

  • Jeffrey B Travers, MD, PhD · Wright State University

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-12-07
Primary Completion
2025-12-31
Completion
2025-12-31
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04122456 on ClinicalTrials.gov