FDG PET/CT in Monitoring Very Early Therapy Response in Patients With Glioblastoma
NCT02902757 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 7
Last updated 2025-12-17
Summary
This pilot clinical trial studies fluordeoxyglucose (fludeoxyglucose) F-18 (FDG) positron emission tomography (PET)/computed tomography (CT) in monitoring very early therapy response in patients with glioblastoma. Diagnostic procedures, such as FDG PET/CT, may help measure a patient's response to earlier treatment. Chemotherapy can induce very rapid changes to the tumor's glucose consumption which can be measured with imaging. FDG PET/CT shortly after the start of therapy may help identify very early therapy response in patients with glioblastoma.
Conditions
Interventions
- PROCEDURE
-
Computed Tomography
Undergo FDG PET/CT
- RADIATION
-
Fludeoxyglucose F-18
Undergo FDG PET/CT
- PROCEDURE
-
Positron Emission Tomography
Undergo FDG PET/CT
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
National Institutes of Health (NIH)
collaborator NIH -
Jonsson Comprehensive Cancer Center
lead OTHER
Principal Investigators
-
Johannes Czernin, MD · UCLA / Jonsson Comprehensive Cancer Center
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-08-25
- Primary Completion
- 2025-01-29
- Completion
- 2025-01-29
Countries
- United States
Study Locations
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