Clinical Trials

NCT06348199 | ACTIVE_NOT_RECRUITING | PHASE3

555 participants

A Study to Compare the Efficacy, Safety, Pharmacokinetics, and Immunogenicity Between SB27 and Keytruda in Subjects With Metastatic Non-squamous Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-03-12
Completion:: 2026-03-10

Conditions

Non-small Cell Lung Cancer Stage IV

Interventions

DRUG

No Results Yet

NCT06345963 | RECRUITING | NA

120 participants

Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 1)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-05-21
Completion:: 2029-05-01

Conditions

Schizophrenia

Interventions

DEVICE

No Results Yet

NCT06342440 | RECRUITING

2000 participants

Early Detection of Advanced Adenomas and Colorectal Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-07
Start Date:: 2020-03-15
Completion:: 2028-06-18

Conditions

Colorectal Cancer
Colorectal Neoplasms
Colorectal Polyp
Colorectal Adenocarcinoma
Colorectal Disorders
Colorectal Dysplasia
Colorectal Cancer Stage I
Colorectal Cancer Stage II
Colorectal Cancer Stage III
Colorectal Cancer Stage IV
Colorectal Neoplasms Malignant
Colorectal Serrated Adenocarcinoma
Colorectal Adenoma With Severe Dysplasia
Colorectal Adenoma With Mild Dysplasia
Colorectal Adenoma With Moderate Dysplasia
Colorectal Adenoma and Carcinoma 1
Colorectal Adenomatous Polyp
Colorectal Adenocarcinoma Metastatic in the Liver

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06342414 | RECRUITING

400 participants

An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-03-15
Completion:: 2028-06-18

Conditions

Hepatocellular Carcinoma
Intrahepatic Cholangiocarcinoma
Cholangiocarcinoma
Primary Liver Cancer
Primary Liver Carcinoma
Hepatic Cancer
Hepatic Carcinoma

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06342401 | RECRUITING

400 participants

Early Onset Colorectal Cancer Detection

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-07
Start Date:: 2023-04-15
Completion:: 2028-06-18

Conditions

Colorectal Cancer
Colorectal Neoplasms
Colorectal Adenocarcinoma
Colorectal Cancer Stage I
Colorectal Cancer Stage IV
Colorectal Cancer Stage II
Colorectal Cancer Stage III
Colorectal Neoplasms Malignant

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06336252 | COMPLETED | NA

130 participants

Technology Assisted Nudging to Increase Physical Activity Among Hospitalised Medical Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-05-03
Completion:: 2025-06-07

Conditions

COPD
Heart Failure
Parkinson Disease
Arthritis
Old Age; Cachexia
Stroke Sequelae

Interventions

BEHAVIORAL

No Results Yet

NCT06327477 | RECRUITING | PHASE1/PHASE2

28 participants

Proton-Spatially Fractionated Radiotherapy and Standard Radiation Therapy for the Treatment of Newly Diagnosed Retroperitoneal Soft Tissue Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-04-02
Completion:: 2028-07-01

Conditions

Retroperitoneal Sarcoma

Interventions

PROCEDURE
RADIATION

No Results Yet

NCT06318143 | RECRUITING | NA

900 participants

mAnaging siCkle CELl disEase Through incReased AdopTion of hydroxyurEa in Nigeria

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-07-01
Completion:: 2027-06-30

Conditions

Sickle Cell Disease

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06317675 | TERMINATED | PHASE2

26 participants

Osteopathic Manipulative Treatment for Gastro-oesophageal Reflux Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-02-18
Completion:: 2026-01-11

Conditions

Gastro-oesophageal Reflux Disease

Interventions

OTHER

No Results Yet

NCT06314958 | RECRUITING

400 participants

Stage II/III Colorectal Cancer Recurrence

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-07
Start Date:: 2023-03-15
Completion:: 2028-06-18

Conditions

Colorectal Cancer
Colorectal Adenocarcinoma
Colorectal Cancer Stage II
Colorectal Cancer Stage III
Colorectal Cancer Recurrent

Interventions

OTHER

No Results Yet

NCT06312553 | NOT_YET_RECRUITING | NA

80 participants

Remotely Delivered Mindfulness-Based Diabetes Education

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2026-08-01
Completion:: 2027-06-30

Conditions

Type 2 Diabetes

Interventions

BEHAVIORAL

No Results Yet

NCT06311682 | RECRUITING | PHASE3

195 participants

A Trial to Evaluate the Efficacy and Safety of Tralokinumab in Combination With Topical Corticosteroids in Children and Infants With Moderate-to-severe Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-06-10
Completion:: 2026-10-20

Conditions

Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT06302725 | COMPLETED | NA

278 participants

Vaginal Self-sampling for Detecting High-risk Human Papillomavirus Cervical Infection in Patients With Immune-mediated Inflammatory Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-03-01
Completion:: 2026-06-16

Conditions

HPV Infection
Systemic Disease

Interventions

PROCEDURE

No Results Yet

NCT06293430 | NOT_YET_RECRUITING

50 participants

Registry on Luma Vision's VERAFEYE System (ENLIgHT)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-07
Start Date:: 2027-02-15
Completion:: 2027-10-15

Conditions

Atrial Fibrillation
Left Atrial Appendage Closure
Atrial Arrhythmia

Interventions

DEVICE

No Results Yet

NCT06288659 | ACTIVE_NOT_RECRUITING | NA

372 participants

aSAH Treatment Based on Intraventricular ICP Monitoring: A Prospective, Multicenter, Randomized and Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-07-19
Completion:: 2026-07-29

Conditions

Aneurysmal Subarachnoid Hemorrhage
Intacranial Hypertension

Interventions

DEVICE

No Results Yet

NCT06281977 | RECRUITING | PHASE3

192 participants

Study Evaluating Dexmedetomidine in the Acute Treatment of Electrical Storm

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-05-08
Completion:: 2027-05-08

Conditions

Ventricular Tachycardia
Ventricular Arrhythmias
Ventricular Fibrillation
Recurrent Ventricular Tachycardia

Interventions

DRUG

No Results Yet

NCT06275698 | RECRUITING | NA

100 participants

HONEY for the Treatment of POst-Tonsillectomy Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2023-09-04
Completion:: 2027-07-31

Conditions

Post Surgical Pain
Analgesia

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06272539 | COMPLETED | NA

36 participants

Spinal Cord Stimulation Combined With Exercise in Persistent Spinal Pain Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-04-09
Completion:: 2026-01-01

Conditions

Failed Back Surgery Syndrome

Interventions

PROCEDURE

No Results Yet

NCT06268210 | ACTIVE_NOT_RECRUITING | PHASE2

160 participants

Neoadjuvant Lazertinib With or Without Chemotherapy for Patients With EGFR-mutated Resectable Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2022-02-07
Completion:: 2028-05-31

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06249191 | RECRUITING | PHASE1/PHASE2

40 participants

Mosunetuzumab With Chemotherapy for the Treatment of Patients With Untreated C-Myc Rearrangement Positive High Grade B Cell Lymphoma or Diffuse Large B Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-06-13
Completion:: 2026-12-01

Conditions

Diffuse Large B-Cell Lymphoma
High Grade B-Cell Lymphoma

Interventions

DRUG
PROCEDURE
BIOLOGICAL

No Results Yet

NCT06248619 | ACTIVE_NOT_RECRUITING | PHASE3

89 participants

A Trial to Investigate Teprotumumab Subcutaneous Administration Compared With Placebo in Male and Female Adult Participants With Moderate-to-severe Active Thyroid Eye Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-07-05
Completion:: 2025-12-23

Conditions

Thyroid Eye Disease

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT06246929 | RECRUITING | NA

400 participants

Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive Decline

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2025-01-10
Completion:: 2028-12-15

Conditions

Chronic Pain
Physical Activity
Older Adults
Mild Cognitive Impairment

Interventions

BEHAVIORAL

No Results Yet

NCT06240351 | ACTIVE_NOT_RECRUITING | PHASE4

15 participants

A Study to Evaluate the Safety and Efficacy of Baricitinib in the Treatment of Frontal Fibrosing Alopecia (FFA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-04-22
Completion:: 2026-10-31

Conditions

Frontal Fibrosing Alopecia

Interventions

DRUG

No Results Yet

NCT06234202 | ACTIVE_NOT_RECRUITING | NA

13 participants

The Effect of a Bioactive Fabric Sleeve

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-02-16
Completion:: 2027-06-30

Conditions

Recovery

Interventions

DEVICE

No Results Yet

NCT06217822 | RECRUITING | PHASE1

198 participants

First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-03-07
Completion:: 2028-11-26

Conditions

Advanced Metastatic Castration-resistant Prostate Cancer
Prostate Specific Membrane Antigen (PSMA) Expression

Interventions

DRUG

No Results Yet

NCT06214923 | RECRUITING | NA

78 participants

Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-04-09
Completion:: 2026-05-30

Conditions

Pain
Virtual Reality
Placebo
Temporomandibular Disorder

Interventions

DEVICE
OTHER

No Results Yet

NCT06210880 | COMPLETED

10 participants

Change of Gastric Fluid Volume After Oral Hydration in Fasted Objects

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-02-22
Completion:: 2024-07-04

Conditions

Preoperative Fasting

No Results Yet

NCT06192979 | RECRUITING | NA

41 participants

Optimize First-line Treatment for AL Amyloidosis With t (11; 14)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-01-05
Completion:: 2026-09-30

Conditions

Amyloidosis; Systemic
AL Amyloidosis

Interventions

DRUG

No Results Yet

NCT06188923 | RECRUITING | PHASE2

84 participants

A New Intervention to Improve Function in Veterans With Anxiety and Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2025-08-14
Completion:: 2028-06-30

Conditions

Anxiety and Depression

Interventions

DRUG

No Results Yet

NCT06183944 | COMPLETED

2350 participants

Data Clustering Study With Artificial Intelligence and Phenotyping of Patients With Acute Pulmonary Embolism

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-07
Start Date:: 2023-12-11
Completion:: 2026-07-01

Conditions

Pulmonary Embolism

Interventions

OTHER

No Results Yet

NCT06183437 | RECRUITING | PHASE4

335 participants

The STOP-MED CTRCD Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-03-04
Completion:: 2027-12-31

Conditions

Heart Failure
Cardiotoxicity
Cardiac Toxicity
Antineoplastics Toxicity
Cancer

Interventions

OTHER

No Results Yet

NCT06182163 | COMPLETED | NA

20 participants

Reduce Sedentary Time in Acute Lymphoblastic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-07-01
Completion:: 2025-12-17

Conditions

Acute Lymphoblastic Leukemia (ALL)

Interventions

BEHAVIORAL

No Results Yet

NCT06174779 | COMPLETED | PHASE3

448 participants

A Study to Evaluate Efficacy and Safety of HM11260C in Adult Obesity Patients Without Diabetes Mellitus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-01-03
Completion:: 2025-08-14

Conditions

Obesity

Interventions

DRUG

No Results Yet

NCT06169371 | RECRUITING | PHASE4

50 participants

Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2023-12-28
Completion:: 2030-11-30

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT06165380 | ACTIVE_NOT_RECRUITING | PHASE2

43 participants

Cardenilimab Combined With Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2023-10-23
Completion:: 2026-08-31

Conditions

Esophageal Squamous Cell Carcinoma
Neoadjuvant Therapies

Interventions

DRUG

No Results Yet

NCT06161922 | COMPLETED

600 participants

Real World Patient-Reported Outcomes in Chinese Her2+ EBC Patients Receiving (Neo) Adjuvant Anti-Her2 Based Therapy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-07
Start Date:: 2023-11-07
Completion:: 2025-07-08

Conditions

HER2-positive Breast Cancer

No Results Yet

NCT06160284 | RECRUITING | PHASE1

12 participants

Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2025-05-28
Completion:: 2027-01-31

Conditions

Opioid Use Disorder

Interventions

DRUG

No Results Yet

NCT06153238 | COMPLETED | PHASE1

322 participants

A PK Study to Compare GME751 (Proposed Pembrolizumab Biosimilar) and US-licensed and EU-authorized Keytruda® in Participants With Stage II and III Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-05-15
Completion:: 2026-05-05

Conditions

Melanoma

Interventions

DRUG

No Results Yet

NCT06152185 | COMPLETED | NA

106 participants

Mindfulness App Training for Cardiovascular Health

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-02-06
Completion:: 2026-06-30

Conditions

Cardiovascular Diseases
Mindfulness

Interventions

BEHAVIORAL

No Results Yet

NCT06150989 | ACTIVE_NOT_RECRUITING

80 participants

Black Women's Life Experience On Cardiovascular Health Via Ongoing Monitoring

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-07
Start Date:: 2024-03-04
Completion:: 2026-05-31

Conditions

Cardiovascular Diseases
Heart Disease Risk Factors

Interventions

BEHAVIORAL

No Results Yet