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Early Detection of Advanced Adenomas and Colorectal Cancer

NCT06342440 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 2000

Last updated 2025-06-17

No results posted yet for this study

Summary

This study aims to develop a highly sensitive, specific, and cost-effective blood assay for early detection of colorectal adenomas and cancer, using advanced machine learning and state-of-the-art biological analyses.

Conditions

  • Colorectal Cancer
  • Colorectal Neoplasms
  • Colorectal Polyp
  • Colorectal Adenocarcinoma
  • Colorectal Disorders
  • Colorectal Dysplasia
  • Colorectal Cancer Stage I
  • Colorectal Cancer Stage II
  • Colorectal Cancer Stage III
  • Colorectal Cancer Stage IV
  • Colorectal Neoplasms Malignant
  • Colorectal Serrated Adenocarcinoma
  • Colorectal Adenoma With Severe Dysplasia
  • Colorectal Adenoma With Mild Dysplasia
  • Colorectal Adenoma With Moderate Dysplasia
  • Colorectal Adenoma and Carcinoma 1
  • Colorectal Adenomatous Polyp
  • Colorectal Adenocarcinoma Metastatic in the Liver

Interventions

DIAGNOSTIC_TEST

DENEB

A panel of circulating microRNA, whose expression level is tested in cell-free and exosome-derived samples.

Sponsors & Collaborators

  • City of Hope Medical Center

    lead OTHER

Principal Investigators

  • Ajay Goel, PhD · City of Hope Medical Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-03-15
Primary Completion
2026-06-18
Completion
2026-06-18

Countries

  • United States
  • China
  • Italy
  • Japan
  • Spain

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06342440 on ClinicalTrials.gov