An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer
NCT06342414 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 400
Last updated 2026-04-03
Summary
It is sometimes difficult to precisely understand whether a primary liver cancer is a hepatocellular carcinoma or a cholangiocarcinoma. The researchers will develop and validate a liquid biopsy, based on exosomal content analysis and powered by machine learning, to help clinicians differentiate these two cancers before surgery.
Conditions
- Hepatocellular Carcinoma
- Intrahepatic Cholangiocarcinoma
- Cholangiocarcinoma
- Primary Liver Cancer
- Primary Liver Carcinoma
- Hepatic Cancer
- Hepatic Carcinoma
Interventions
- DIAGNOSTIC_TEST
-
ELUCIDATE
ELUCIDATE (Evaluation of Liver Cholangiocarcinoma Intrahepatic)
Sponsors & Collaborators
-
City of Hope Medical Center
lead OTHER
Principal Investigators
-
Ajay Goel, PhD · City of Hope Medical Center
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-03-15
- Primary Completion
- 2026-06-18
- Completion
- 2026-06-18
Countries
- United States
- Japan
Study Locations
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