Clinical Trials

NCT04645602 | RECRUITING | PHASE2

20 participants

Merck IIT: RRP Pembro and Lenvatinib

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2025-07-18

Completion:

2027-12-31

Conditions

• Human Papilloma Virus
• Recurrent Respiratory Papillomatosis
• Pulmonary Disease

Interventions

• DRUG

No Results Yet

NCT04626635 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

548 participants

A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-12-21

Completion:

2026-11-13

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT04621396 | RECRUITING

600 participants

The Next Generation Longitudinal Birth Cohort Diabetes Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-02

Start Date:

2013-09-30

Completion:

2026-12-31

Conditions

• Type 2 Diabetes
• Gestational Diabetes Mellitus

Interventions

• OTHER

No Results Yet

NCT04609904 | COMPLETED | PHASE3

2187 participants

Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (LOGOS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-03-01

Completion:

2025-03-20

Conditions

• Asthma

Interventions

• DRUG

Results Available

NCT04595825 | COMPLETED | PHASE2

77 participants

CM-101 in PSC Patients -The SPRING Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-10-01

Completion:

2025-01-10

Conditions

• Primary Sclerosing Cholangitis

Interventions

• BIOLOGICAL
• OTHER

Results Available

NCT04576117 | ACTIVE_NOT_RECRUITING | PHASE3

300 participants

A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-02-16

Completion:

2026-12-30

Conditions

• Recurrent Low Grade Astrocytoma
• Recurrent WHO Grade 2 Glioma
• Refractory Low Grade Astrocytoma
• Refractory Low Grade Glioma
• Refractory WHO Grade 1 Glioma

Interventions

• PROCEDURE
• OTHER
• DRUG

No Results Yet

NCT04562870 | ACTIVE_NOT_RECRUITING | PHASE2

112 participants

A Study to Evaluate Single Agent Selinexor Versus Physician's Choice in Participants With Previously Treated Myelofibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-03-17

Completion:

2026-09-30

Conditions

• Myelofibrosis

Interventions

• OTHER
• DRUG

No Results Yet

NCT04541446 | COMPLETED | NA

773 participants

Study Dynamic Haptic Robotic Trainer (DHRT) and DHRT+ for Central Venous Catherization Insertion Training for Surgical Residents

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-08-19

Completion:

2025-06-30

Conditions

• Central Line Complication
• Central Line Infection

Interventions

• OTHER

No Results Yet

NCT04535193 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

10 participants

Open-Label Study of 18F-mFBG for Imaging Myocardial Sympathetic Innervation

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-11-05

Completion:

2025-03-07

Conditions

• Cardiovascular Diseases

Interventions

• DRUG

No Results Yet

NCT04509037 | WITHDRAWN

0 participants

Evaluation of Breast Reduction Techniques

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-02

Start Date:

2012-08-08

Completion:

2026-06-02

Conditions

• Breast Reductions

No Results Yet

NCT04504825 | ACTIVE_NOT_RECRUITING | PHASE3

125 participants

A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis (CARES)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-08-25

Completion:

2025-05-10

Conditions

• AL Amyloidosis

Interventions

• DRUG
• OTHER

Results Available

NCT04492410 | COMPLETED | NA

214 participants

COVID-19 Infection Screening in Cancer Patients (NEOSCREENCOVID)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-07-21

Completion:

2021-05-12

Conditions

• Cancer

Interventions

• OTHER

Results Available

NCT04444609 | COMPLETED

161 participants

PROSAIC-19 - Prospective Longitudinal Assessment in a COVID-19 Infected Cohort

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-02

Start Date:

2020-06-18

Completion:

2024-06-17

Conditions

• COVID-19
• SARS-CoV 2
• ARDS, Human
• Immune System Disorder

Interventions

• OTHER

No Results Yet

NCT04442022 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

501 participants

A Study of Rituximab-Gemcitabine-Dexamethasone-Platinum (R-GDP) With or Without Selinexor in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-09-03

Completion:

2026-12-31

Conditions

• Relapsed/Refractory Diffuse Large B-cell Lymphoma

Interventions

• DRUG

No Results Yet

NCT04427761 | ACTIVE_NOT_RECRUITING

55 participants

A Study of the Life Changes Experienced by Patients With Pancreatic Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-02

Start Date:

2020-06-05

Completion:

2027-06-05

Conditions

• Pancreatic Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT04401995 | COMPLETED | PHASE2

9 participants

Study of TLR9 Agonist Vidutolimod (CMP-001) in Combination With Nivolumab vs. Nivolumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-09-02

Completion:

2024-08-16

Conditions

• Melanoma

Interventions

• DRUG
• BIOLOGICAL
• OTHER

Results Available

NCT04401982 | RECRUITING | PHASE4

50 participants

Measuring the Effects of Netarsudil, Latanoprost, and Combination Therapy on Episcleral and Retinal Blood Flow in Ocular Hypertension and Glaucoma Suspects

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2026-07-02

Completion:

2027-03-17

Conditions

• Ocular Hypertension
• Suspect Glaucoma

Interventions

• DRUG

No Results Yet

NCT04336722 | COMPLETED | PHASE3

254 participants

Efficacy and Safety of Odevixibat in Children With Biliary Atresia Who Have Undergone a Kasai HPE (BOLD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-07-08

Completion:

2026-06-22

Conditions

• Biliary Atresia

Interventions

• DRUG

No Results Yet

NCT04300894 | COMPLETED | NA

1757 participants

"Mamma Mia" for Perinatal Health and Wellness

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-10-15

Completion:

2025-06-01

Conditions

• Perinatal Depression

Interventions

• DEVICE
• OTHER

Results Available

NCT04265950 | COMPLETED | PHASE4

97 participants

Establishing Optimal Number of Doses for HPV Vaccination in Children and Adolescents Living With HIV, OPTIMO Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2022-03-10

Completion:

2026-05-12

Conditions

• HIV Infection

Interventions

• BIOLOGICAL

No Results Yet

NCT04264897 | COMPLETED | PHASE3

166 participants

Antecedent Metabolic Health and Metformin Aging Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-07-29

Completion:

2025-03-12

Conditions

• Aging
• Insulin Sensitivity
• Chronic Disease
• Mitochondria
• Insulin Resistance

Interventions

• DRUG

Results Available

NCT04261153 | COMPLETED | NA

55 participants

Use of Cognitive Stimulation Software for Patients Over the Age of 70 Followed for Breast Cancer: COG-TAB-AGE Feasibility Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-06-05

Completion:

2022-03-08

Conditions

• Breast Cancer

Interventions

• OTHER

Results Available

NCT04250155 | COMPLETED | PHASE1

195 participants

An Open-Label Dose-Escalation Study to Evaluate XmAb24306 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-03-09

Completion:

2026-05-27

Conditions

• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT04225429 | NO_LONGER_AVAILABLE

Tazemetostat Expanded Access Program for Adults With Epithelioid Sarcoma

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-07-02

Conditions

• Epithelioid Sarcoma

Interventions

• DRUG

No Results Yet

NCT04214067 | ACTIVE_NOT_RECRUITING | PHASE3

164 participants

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-04-09

Completion:

2025-12-30

Conditions

• Endometrial Endometrioid Adenocarcinoma
• Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
• Stage II Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8

Interventions

• PROCEDURE
• RADIATION
• BIOLOGICAL
• OTHER

No Results Yet

NCT04213365 | COMPLETED | NA

20 participants

Management of Cognitive Difficulties After Cancer Treatments in Women Treated for Breast Cancer: Feasibility Study (Step 1 of the Cog-Stim Protocol)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-01-24

Completion:

2021-11-02

Conditions

• Breast Cancer

Interventions

• OTHER

Results Available

NCT04189471 | RECRUITING

5000 participants

Improving Outcomes for Patients With Life-Threatening Neurologic Illness

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-02

Start Date:

2014-09-08

Completion:

2034-01-01

Conditions

• Intracerebral Hemorrhage
• Subarachnoid Hemorrhage
• Intraventricular Hemorrhage
• Nontraumatic Haemorrhage
• Status Epilepticus

No Results Yet

NCT04131413 | RECRUITING | PHASE1

48 participants

HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-09-14

Completion:

2027-12-31

Conditions

• Human Papillomavirus Type 16
• Cervical Intraepithelial Neoplasia Grade II
• Cervical Intraepithelial Neoplasia, Grade III

Interventions

• DRUG

No Results Yet

NCT04104672 | ACTIVE_NOT_RECRUITING | PHASE1

196 participants

A Study to Evaluate the Safety and Tolerability of AB680 in Participants With Gastrointestinal Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2019-11-06

Completion:

2027-05-31

Conditions

• Advanced Pancreatic Cancer

Interventions

• DRUG

No Results Yet

NCT04085523 | COMPLETED | PHASE2

57 participants

A Dose Escalation Trial Evaluating Safety, Efficacy, and Pharmacokinetics of TransCon CNP Administered Once Weekly in Prepubertal Children With Achondroplasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-06-24

Completion:

2022-09-27

Conditions

• Achondroplasia

Interventions

• DRUG

Results Available

NCT04000880 | COMPLETED | NA

603 participants

Adapting Multiple Behavior Interventions That Effectively Improve Cancer Survivor Health Cancer Survivor Health

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-03-04

Completion:

2025-04-01

Conditions

• Breast Cancer
• Colorectal Cancer
• Endometrial Cancer
• Kidney Cancer
• Multiple Myeloma
• Ovary Cancer
• Prostate Cancer
• Thyroid Cancer
• Non-Hodgkin Lymphoma

Interventions

• BEHAVIORAL
• OTHER

Results Available

NCT03990428 | RECRUITING

250 participants

Supportive Care Needs of Caregivers of People With Erdheim-Chester Disease and Other Histiocytic Diseases

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-02

Start Date:

2019-06-14

Completion:

2027-06-30

Conditions

• Supportive Care Needs of Caregivers

Interventions

• BEHAVIORAL

No Results Yet

NCT03987581 | COMPLETED | NA

151 participants

Cost Effectiveness of Combined Contingency Management and Cognitive Behavioral Therapy for Alcohol Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2019-11-26

Completion:

2024-04-11

Conditions

• Alcohol Drinking
• Veterans

Interventions

• BEHAVIORAL

Results Available

NCT03978442 | COMPLETED | PHASE4

115 participants

CPT-SMART for Treatment of PTSD and Cigarette Smoking

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2019-11-07

Completion:

2025-10-08

Conditions

• Smoking
• Stress Disorders, Post-Traumatic

Interventions

• BEHAVIORAL
• DRUG

Results Available

NCT03972930 | ACTIVE_NOT_RECRUITING | PHASE2

48 participants

Hypofractionated Radiotherapy for Soft Tissue Sarcomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2019-06-11

Completion:

2024-11-28

Conditions

• Soft Tissue Sarcoma

Interventions

• RADIATION

Results Available

NCT03968003 | COMPLETED | NA

165 participants

Impact of Dietary Fiber as Prebiotics on Intestinal Microbiota in Obese Thai Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2017-08-01

Completion:

2020-06-30

Conditions

• Obesity

Interventions

• DIETARY_SUPPLEMENT

Results Available

NCT03958474 | COMPLETED | EARLY_PHASE1

12 participants

Neurobehavioral Mechanisms of Choice in Opioid Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2019-08-16

Completion:

2025-07-10

Conditions

• Opioid Use Disorder

Interventions

• DRUG

Results Available

NCT03952585 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

384 participants

De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2019-10-09

Completion:

2024-03-01

Conditions

• Basaloid Squamous Cell Carcinoma
• Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Oropharyngeal Squamous Cell Carcinoma
• Papillary Squamous Cell Carcinoma
• Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Squamous Cell Carcinoma

Interventions

• PROCEDURE
• DRUG
• OTHER
• RADIATION
• BIOLOGICAL

Results Available

NCT03919955 | COMPLETED | PHASE2

117 participants

A Novel Pharmacological Therapy for Obstructive Sleep Apnea

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2019-09-03

Completion:

2023-09-07

Conditions

• Sleep Apnea

Interventions

• DRUG

Results Available

NCT03911050 | COMPLETED | NA

12 participants

Scavenging of Reactive Carbonyl Species by Apple Polyphenols in Human

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2018-11-26

Completion:

2018-12-14

Conditions

• Human Health
• Polyphenols
• Pharmacokinetics

Interventions

• DIETARY_SUPPLEMENT

Results Available