Trial Outcomes & Findings for COVID-19 Infection Screening in Cancer Patients (NEOSCREENCOVID) (NCT NCT04492410)

NCT ID: NCT04492410

Last Updated: 2026-07-02

Results Overview

Results for IgG testing. The number of samples may exceed the number of participants as re-testing was allowed.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

214 participants

Primary outcome timeframe

Baseline (Day 0)

Results posted on

2026-07-02

Participant Flow

Participant milestones

Participant milestones
Measure
Experimental Arm
screening using a rapid serological test with a drop of blood from a finger prick.
Overall Study
STARTED
214
Overall Study
COMPLETED
154
Overall Study
NOT COMPLETED
60

Reasons for withdrawal

Reasons for withdrawal
Measure
Experimental Arm
screening using a rapid serological test with a drop of blood from a finger prick.
Overall Study
Protocol Violation
3
Overall Study
Death
19
Overall Study
Withdrawal by Subject
3
Overall Study
Lost to Follow-up
12
Overall Study
Missed visit window / Not seen within protocol-defined timeframe
23

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Experimental Arm
n=211 Participants
screening using a rapid serological test with a drop of blood from a finger prick.
Age, Continuous
64.81 years
STANDARD_DEVIATION 12.68 • n=211 Participants
Sex: Female, Male
Female
117 Participants
n=211 Participants
Sex: Female, Male
Male
94 Participants
n=211 Participants
Presence of COVID-19 Symptoms
No
190 Participants
n=210 Participants • Missing data for 1 participant
Presence of COVID-19 Symptoms
Yes
20 Participants
n=210 Participants • Missing data for 1 participant

PRIMARY outcome

Timeframe: Baseline (Day 0)

Population: The analysis population includes all participants who met the study eligibility criteria. Of the 214 participants enrolled, 3 were excluded from the analysis set because they were found to be ineligible (inclusion errors) after enrollment. The number of tests exceeds the number of participants because re-testing was permitted per protocol if the initial sample was inconclusive or for clinical monitoring. All valid test results obtained within the specified time frame are reported.

Results for IgG testing. The number of samples may exceed the number of participants as re-testing was allowed.

Outcome measures

Outcome measures
Measure
Experimental Arm
n=223 Numbers of tests
screening using a rapid serological test with a drop of blood from a finger prick.
Healthcare Professionals
Healthcare professionals (physicians, nurses, or laboratory technicians) involved in the COVID-19 screening process who completed the satisfaction/feedback survey regarding the testing techniques.
Number of IgG Test Results at Inclusion
Positive (Samples)
21 Numbers of tests
Number of IgG Test Results at Inclusion
Equivocal Positive (Samples)
41 Numbers of tests
Number of IgG Test Results at Inclusion
Negative (Samples)
153 Numbers of tests
Number of IgG Test Results at Inclusion
Equivocal Negative (Samples)
2 Numbers of tests
Number of IgG Test Results at Inclusion
Non-contributory (Samples)
4 Numbers of tests
Number of IgG Test Results at Inclusion
Result not available
2 Numbers of tests

PRIMARY outcome

Timeframe: Baseline (Day 0)

Population: The analysis population includes all participants who met the study eligibility criteria. Of the 214 participants enrolled, 3 were excluded from the analysis set because they were found to be ineligible (inclusion errors) after enrollment. The number of tests exceeds the number of participants because re-testing was permitted per protocol if the initial sample was inconclusive or for clinical monitoring. All valid test results obtained within the specified time frame are reported.

Results for IgM testing. The number of samples may exceed the number of participants as re-testing was allowed.

Outcome measures

Outcome measures
Measure
Experimental Arm
n=218 Numbers of tests
screening using a rapid serological test with a drop of blood from a finger prick.
Healthcare Professionals
Healthcare professionals (physicians, nurses, or laboratory technicians) involved in the COVID-19 screening process who completed the satisfaction/feedback survey regarding the testing techniques.
Number of IgM Test Results at Inclusion
Positive (Samples)
24 Tests
Number of IgM Test Results at Inclusion
Equivocal Positive (Samples)
54 Tests
Number of IgM Test Results at Inclusion
Negative (Samples)
135 Tests
Number of IgM Test Results at Inclusion
Equivocal Negative (Samples)
1 Tests
Number of IgM Test Results at Inclusion
Non-contributory (Samples)
4 Tests

SECONDARY outcome

Timeframe: Day 1

Population: The analysis population includes all participants available at this time point (N=211). The total number of responses in the categories may be lower than the overall number of participants analyzed due to missing data or incomplete questionnaires for some variables (e.g., participants who declined to answer specific questions).

The assessment of the perception of the rapid serological test for patient and health care professional will be measured in terms of Pain, simplicity, rapidity and satisfaction, reported on a questionnaire: * • Pain: The pain assessment will be performed using a visual analog scale (VAS). The score will be graded between 0 (absence of pain) to 10 (maximum pain) * • Simplicity: The assessment of the satisfaction of care will be carried out using a Likert scale with 4 modalities. The score will be graded between "Poor" to "Very Good". * • Rapidity: The assessment of the satisfaction of care will be carried out using a Likert scale with 4 modalities. The score will be graded between "Poor" to "Very Good". * • Satisfaction with care: The assessment of the satisfaction of care will be carried out using a Likert scale with 4 modalities. The score will be graded between "Poor" to "Very Good"

Outcome measures

Outcome measures
Measure
Experimental Arm
n=211 Participants
screening using a rapid serological test with a drop of blood from a finger prick.
Healthcare Professionals
n=45 Participants
Healthcare professionals (physicians, nurses, or laboratory technicians) involved in the COVID-19 screening process who completed the satisfaction/feedback survey regarding the testing techniques.
To Evaluate Patient's and Health Care Professional's Perception About the Rapid Serological Test.
Speed · Not at All Satisfied
1 Participants
0 Participants
To Evaluate Patient's and Health Care Professional's Perception About the Rapid Serological Test.
Speed · Not available
3 Participants
0 Participants
To Evaluate Patient's and Health Care Professional's Perception About the Rapid Serological Test.
Simplicity · Slightly Satisfied
3 Participants
1 Participants
To Evaluate Patient's and Health Care Professional's Perception About the Rapid Serological Test.
Simplicity · Not at All Satisfied
0 Participants
0 Participants
To Evaluate Patient's and Health Care Professional's Perception About the Rapid Serological Test.
Simplicity · Not available
5 Participants
0 Participants
To Evaluate Patient's and Health Care Professional's Perception About the Rapid Serological Test.
Speed · Very Satisfied
188 Participants
35 Participants
To Evaluate Patient's and Health Care Professional's Perception About the Rapid Serological Test.
Speed · Somewhat Satisfied
16 Participants
10 Participants
To Evaluate Patient's and Health Care Professional's Perception About the Rapid Serological Test.
Speed · Slightly Satisfied
3 Participants
0 Participants
To Evaluate Patient's and Health Care Professional's Perception About the Rapid Serological Test.
Simplicity · Very Satisfied
189 Participants
35 Participants
To Evaluate Patient's and Health Care Professional's Perception About the Rapid Serological Test.
Simplicity · Somewhat Satisfied
14 Participants
9 Participants
To Evaluate Patient's and Health Care Professional's Perception About the Rapid Serological Test.
SATISFACTION · Very Satisfied
187 Participants
9 Participants
To Evaluate Patient's and Health Care Professional's Perception About the Rapid Serological Test.
SATISFACTION · Somewhat Satisfied
14 Participants
15 Participants
To Evaluate Patient's and Health Care Professional's Perception About the Rapid Serological Test.
SATISFACTION · Slightly Satisfied
6 Participants
14 Participants
To Evaluate Patient's and Health Care Professional's Perception About the Rapid Serological Test.
SATISFACTION · Not at All Satisfied
1 Participants
6 Participants
To Evaluate Patient's and Health Care Professional's Perception About the Rapid Serological Test.
SATISFACTION · Not available
3 Participants
0 Participants

SECONDARY outcome

Timeframe: Day 1

Population: The analysis population includes all participants who met the study eligibility criteria. Of the 214 participants enrolled, 3 were excluded from the analysis set because they were found to be ineligible (inclusion errors) after enrollment. The number of tests exceeds the number of participants because re-testing was permitted per protocol if the initial sample was inconclusive or for clinical monitoring. All valid test results obtained within the specified time frame are reported.

Results for RT-PCR testing. The number of samples may exceed the number of participants as re-testing was allowed.

Outcome measures

Outcome measures
Measure
Experimental Arm
n=66 Number of RT-PCR Test Results at Inclusi
screening using a rapid serological test with a drop of blood from a finger prick.
Healthcare Professionals
Healthcare professionals (physicians, nurses, or laboratory technicians) involved in the COVID-19 screening process who completed the satisfaction/feedback survey regarding the testing techniques.
Number of RT-PCR Test Results at Inclusion
Negative
59 Number of RT-PCR Test Results at Inclusi
Number of RT-PCR Test Results at Inclusion
Positive
7 Number of RT-PCR Test Results at Inclusi

SECONDARY outcome

Timeframe: Day 1

Population: The analysis population includes all participants available at this time point (N=211). The total number of responses in the categories may be lower than the overall number of participants analyzed due to missing data or incomplete questionnaires for some variables (e.g., participants who declined to answer specific questions).

The assessment of the perception of the rapid serological test for patient will be measured in terms of Pain, simplicity, rapidity and satisfaction, reported on a questionnaire: * • Pain: The pain assessment will be performed using a visual analog scale (VAS). The score will be graded between 0 (absence of pain) to 10 (maximum pain) * • Simplicity: The assessment of the satisfaction of care will be carried out using a Likert scale with 4 modalities. The score will be graded between "Poor" to "Very Good". * • Rapidity: The assessment of the satisfaction of care will be carried out using a Likert scale with 4 modalities. The score will be graded between "Poor" to "Very Good". * • Satisfaction with care: The assessment of the satisfaction of care will be carried out using a Likert scale with 4 modalities. The score will be graded between "Poor" to "Very Good"

Outcome measures

Outcome measures
Measure
Experimental Arm
n=211 Participants
screening using a rapid serological test with a drop of blood from a finger prick.
Healthcare Professionals
Healthcare professionals (physicians, nurses, or laboratory technicians) involved in the COVID-19 screening process who completed the satisfaction/feedback survey regarding the testing techniques.
To Evaluate Patient's Pain Perception About the Rapid Serological Test.
0
163 Participants
To Evaluate Patient's Pain Perception About the Rapid Serological Test.
2
14 Participants
To Evaluate Patient's Pain Perception About the Rapid Serological Test.
1
19 Participants
To Evaluate Patient's Pain Perception About the Rapid Serological Test.
3
5 Participants
To Evaluate Patient's Pain Perception About the Rapid Serological Test.
4
3 Participants
To Evaluate Patient's Pain Perception About the Rapid Serological Test.
5
3 Participants
To Evaluate Patient's Pain Perception About the Rapid Serological Test.
6
1 Participants
To Evaluate Patient's Pain Perception About the Rapid Serological Test.
Not available
3 Participants

Adverse Events

Experimental Arm

Serious events: 0 serious events
Other events: 0 other events
Deaths: 19 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Director of Clinical Trials

Centre Antoine Lacassagne

Phone: +33 4 92 03 10 00

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place