Clinical Trials

NCT04770870 | ACTIVE_NOT_RECRUITING | NA

94 participants

Post Approval Study2: Hintermann Series H3 Total Ankle Replacement System

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2022-02-01

Completion:

2029-09-01

Conditions

• Osteoarthritis Ankle
• Post-Traumatic Osteoarthritis of Ankle
• Osteoarthritis of Ankle Secondary to Inflammatory Arthritis (Disorder)

Interventions

• DEVICE

No Results Yet

NCT04770090 | ACTIVE_NOT_RECRUITING | NA

200 participants

Research of Circulating Tumor Cells Released During Cervical Cancer Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2022-03-10

Completion:

2022-12-05

Conditions

• Cervical Cancer Stage IA1
• Cervical Cancer Stage IB1
• Cervical Cancer Stage IA2
• Cervical Cancer Stage IB2

Interventions

• OTHER

No Results Yet

NCT04727307 | ACTIVE_NOT_RECRUITING | PHASE2

202 participants

Neoadjuvant Atezo, Adjuvant Atezo + Beva Combined With RF Ablation of Small HCC: a Multicenter Randomized Phase II Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2021-02-23

Completion:

2028-02-29

Conditions

• Hepatocellular Carcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04708613 | RECRUITING

300 participants

University of Pittsburgh Brain Health Initiative

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-22

Start Date:

2019-11-18

Completion:

2026-12-31

Conditions

• Traumatic Brain Injury

Interventions

• DIAGNOSTIC_TEST
• DRUG

No Results Yet

NCT04668300 | ACTIVE_NOT_RECRUITING | PHASE2

75 participants

Oleclumab and Durvalumab for the Treatment of Recurrent, Refractory, or Metastatic Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-11-26

Completion:

2027-06-30

Conditions

• Metastatic Angiosarcoma
• Metastatic Dedifferentiated Liposarcoma
• Metastatic Osteosarcoma
• Recurrent Angiosarcoma
• Recurrent Dedifferentiated Liposarcoma
• Recurrent Osteosarcoma
• Refractory Dedifferentiated Liposarcoma
• Refractory Osteosarcoma

Interventions

• BIOLOGICAL

No Results Yet

NCT04626050 | RECRUITING | NA

120 participants

General Psychological Distress, PTSD, and Co-Morbidities in Healthcare Workers Consequent to Occupational Trauma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2022-01-20

Completion:

2028-01-31

Conditions

• Post-traumatic Stress Disorder
• Moral Injury

Interventions

• BEHAVIORAL

No Results Yet

NCT04616807 | COMPLETED

53 participants

An Observational Study in Adult Patients With Non-dystrophic Myotonic Disorders

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-22

Start Date:

2020-12-17

Completion:

2026-01-16

Conditions

• Myotonic Dystrophy

Interventions

• DRUG

No Results Yet

NCT04581512 | RECRUITING | PHASE1/PHASE2

70 participants

Study to Evaluate the Safety and Tolerability of EP0042

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-11-02

Completion:

2027-12-31

Conditions

• Acute Myeloid Leukemia
• Chronic Myelomonocytic Leukemia
• Myelodysplastic Syndromes

Interventions

• DRUG

No Results Yet

NCT04581109 | TERMINATED | NA

100 participants

Detection of Viable CTCs Using the EPIDROP Technology in Metastatic Prostate Cancer (EPIDROP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2021-05-27

Completion:

2025-05-12

Conditions

• Prostate Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT04571736 | RECRUITING | NA

220 participants

Pilot Study for Thyroid Surgery by Preoperative Video Support and Personalized and Secure Web Platform

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-11-18

Completion:

2026-11-18

Conditions

• Thyroid

Interventions

• OTHER

No Results Yet

NCT04556916 | RECRUITING | NA

320 participants

Early Detection of Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2021-02-19

Completion:

2023-11-15

Conditions

• Prostate Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04555551 | ACTIVE_NOT_RECRUITING | PHASE1

17 participants

MCARH109 Chimeric Antigen Receptor (CAR) Modified T Cells for the Treatment of Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-09-08

Completion:

2027-08-31

Conditions

• Multiple Myeloma

Interventions

• BIOLOGICAL

No Results Yet

NCT04545762 | RECRUITING | PHASE1

36 participants

Anti-CD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-09-11

Completion:

2026-10-31

Conditions

• Refractory Non-Hodgkin Lymphoma
• Burkitt Lymphoma
• Mantle Cell Lymphoma
• Follicular Lymphoma
• Lymphoplasmacytic Lymphoma
• Primary Mediastinal Large B Cell Lymphoma
• Diffuse Large B Cell Lymphoma
• Small Lymphocytic Lymphoma
• Transformed Lymphoma
• Non-Hodgkin Lymphoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04542161 | ACTIVE_NOT_RECRUITING | PHASE2

95 participants

Assessment of N-Acetylcysteine as Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-09-01

Completion:

2027-04-30

Conditions

• Chronic Fatigue Syndrome
• Myalgic Encephalomyelitis

Interventions

• DRUG

No Results Yet

NCT04523727 | SUSPENDED | PHASE3

45 participants

Study to Evaluate the Safety and Tolerability of Ferric Citrate in Children With Hyperphosphatemia Related to Chronic Kidney Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2022-06-16

Completion:

2026-12-31

Conditions

• Hyperphosphatemia Related to Chronic Kidney Disease

Interventions

• DRUG

No Results Yet

NCT04483726 | COMPLETED | NA

9 participants

Distal Pancreatectomy, Minimally Invasive or Open, for Malignancy (DIPLOMA)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-07-09

Completion:

2021-04-29

Conditions

• Pancreatic Ductal Adenocarcinoma

Interventions

• PROCEDURE

No Results Yet

NCT04471961 | COMPLETED | NA

100 participants

Analyse of Tumour and Constitutional DNA for the Study of the Determinism in Child Neoplasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-07-09

Completion:

2025-06-12

Conditions

• Pediatric Tumor
• Familial Cancer
• Solid Tumor, Childhood
• Hematological Tumor

Interventions

• GENETIC

No Results Yet

NCT04458857 | COMPLETED | PHASE3

235 participants

A Study to Test if Fremanezumab is Effective in Preventing Episodic Migraine in Patients 6 to 17 Years of Age

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-07-15

Completion:

2024-03-13

Conditions

• Migraine

Interventions

• DRUG

Results Available

NCT04458129 | TERMINATED | PHASE2

23 participants

Polyethylene Glycol and Intestinal Inflammation in Cystic Fibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-09-29

Completion:

2022-04-08

Conditions

• Cystic Fibrosis

Interventions

• DRUG

No Results Yet

NCT04429594 | RECRUITING | NA

1000 participants

Study of the Incidence of SARS-CoV-2 Infection (COVID-19)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-07-28

Completion:

2026-09-30

Conditions

• Coronavirus Infections

Interventions

• OTHER

No Results Yet

NCT04419402 | ACTIVE_NOT_RECRUITING | PHASE2

162 participants

Enzalutamide With Lu PSMA-617 Versus Enzalutamide Alone in Men With Metastatic Castration-resistant Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-08-17

Completion:

2024-04-12

Conditions

• Metastatic Castration-Resistant Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT04414917 | SUSPENDED | PHASE2

133 participants

Reducing Opioid Use and Misuse After Wisdom Molar Extractions

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2026-11-30

Completion:

2029-11-30

Conditions

• Pain, Postoperative

Interventions

• DRUG
• DEVICE

No Results Yet

NCT04409080 | TERMINATED | PHASE1

17 participants

REGN7257 in Adult Patients With Severe Aplastic Anemia That Is Refractory to or Relapsed on Immunosuppressive Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2021-01-13

Completion:

2024-10-17

Conditions

• Severe Aplastic Anemia (SAA)

Interventions

• DRUG

No Results Yet

NCT04370574 | RECRUITING

200 participants

Discovery of Soluble Biomarkers for Pancreatic Cancer Using Innovative All-Patient Inclusive Methodology

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-22

Start Date:

2021-01-14

Completion:

2021-01-14

Conditions

• Pancreatic Neoplasms

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04355923 | COMPLETED

1000 participants

Confinement and Spondyloarthritis Treatment

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-22

Start Date:

2020-04-20

Completion:

2020-09-01

Conditions

• Spondyloarthritis

No Results Yet

NCT04334109 | COMPLETED | NA

1100 participants

Comparative Effectiveness of Family DSMES and Standard DSMES Among Diverse Populations

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2021-01-04

Completion:

2023-05-17

Conditions

• Diabetes Mellitus, Type 2

Interventions

• BEHAVIORAL

Results Available

NCT04290754 | ACTIVE_NOT_RECRUITING | NA

636 participants

PATH 2 Purpose: Primary Care and Community-Based Prevention of Mental Disorders in Adolescents

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-01-01

Completion:

2026-07-01

Conditions

• Depression

Interventions

• BEHAVIORAL

No Results Yet

NCT04290000 | RECRUITING

300 participants

Collection of Biological Samples From Patients Treated With CAR-T Cells for Hematological Malignancies

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-22

Start Date:

2020-03-27

Completion:

2025-09-27

Conditions

• Lymphoma and Acute Lymphoblastic Leukemia

Interventions

• OTHER

No Results Yet

NCT04277637 | ACTIVE_NOT_RECRUITING | PHASE1

437 participants

Study of Bcl-2 Inhibitor Sonrotoclax (BGB-11417) in Participants With Mature B-Cell Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-03-24

Completion:

2027-05-31

Conditions

• Mature B-Cell Malignancies

Interventions

• DRUG

No Results Yet

NCT04260698 | COMPLETED | PHASE3

36 participants

Expanded Access of Omidubicel, for Allogeneic Transplantation in Patients With Hematological Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-07-08

Completion:

2025-05-08

Conditions

• Hematological Malignancies

Interventions

• BIOLOGICAL

Results Available

NCT04254549 | TERMINATED | PHASE2

5 participants

Rifaximin in Patients With Diabetic Gastroparesis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2019-06-14

Completion:

2025-04-08

Conditions

• Crohn Disease
• Diabetic Gastroparesis

Interventions

• DRUG

Results Available

NCT04236128 | RECRUITING | NA

670 participants

Home to Stay Mobile App for Colorectal Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2021-05-25

Completion:

2028-06-30

Conditions

• Colorectal Disorders

Interventions

• OTHER

No Results Yet

NCT04213014 | ACTIVE_NOT_RECRUITING | NA

935 participants

Guys/Girls Opt for Activities for Life Trial (GOAL) to Increase Young Adolescents' Physical Activity and Healthy Eating

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-09-26

Completion:

2026-04-30

Conditions

• Obesity, Adolescent

Interventions

• BEHAVIORAL

No Results Yet

NCT04204707 | COMPLETED

294 participants

Patient Reported Outcomes After Surgery for Rectal Endometriosis

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-22

Start Date:

2019-12-09

Completion:

2023-03-31

Conditions

• Endometriosis
• Endometriosis, Rectum
• Endometriosis-related Pain
• Endometriosis; Bowel

Interventions

• OTHER

No Results Yet

NCT04195451 | COMPLETED | NA

150 participants

Re-Energize Fontan

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-08-06

Completion:

2026-02-27

Conditions

• Single-ventricle

Interventions

• OTHER

No Results Yet

NCT04188548 | ACTIVE_NOT_RECRUITING | PHASE1

379 participants

A Study of LY3484356 in Participants With Advanced or Metastatic Breast Cancer or Endometrial Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2019-12-10

Completion:

2020-06-29

Conditions

• Breast Cancer
• Advanced Breast Cancer
• Metastatic Breast Cancer
• Endometrial Cancer

Interventions

• DRUG

No Results Yet

NCT04174066 | RECRUITING

144 participants

From Immune System Damage to Podocyte Cell Damage: Prospective Database and Biological Collection of Patients (Children and Adults) With MGLS and HSFP

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-22

Start Date:

2020-05-20

Completion:

2031-05-20

Conditions

• Nephrotic Syndrome

Interventions

• OTHER

No Results Yet

NCT04167358 | ACTIVE_NOT_RECRUITING | PHASE3

242 participants

Linerixibat Long-term Safety, and Tolerability Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-07-14

Completion:

2026-09-30

Conditions

• Cholestasis

Interventions

• DRUG

No Results Yet

NCT04137562 | ACTIVE_NOT_RECRUITING | PHASE2

118 participants

Safety and Efficacy in Patients With Moderate to Severe Subacute and Chronic Atopic Dermatitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2019-12-11

Completion:

2023-01-26

Conditions

• Atopic Dermatitis

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT04106466 | ACTIVE_NOT_RECRUITING | NA

10 participants

DBS for TRD With the Medtronic Summit RC+S

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2020-01-21

Completion:

2030-12-31

Conditions

• Major Depressive Disorder
• Treatment Resistant Depression

Interventions

• DEVICE

No Results Yet