Clinical Trials Updated in 2025

NCT07311577 | RECRUITING | PHASE2

43 participants

Disitamab Vedotin Combined With Platinum and Bevacizumab as First-Line and Maintenance Therapy for HER2-Expressing, HRD-Negative High-Risk Ovarian Cancer: A Multicenter, Non-Randomized, Single-Arm Phase II Clinical Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2026-01-01
Completion:: 2027-12-30

Conditions

Ovarian Cancer Metastatic
Ovarian Cancer Metastatic Recurrent

Interventions

DRUG

No Results Yet

NCT07311551 | NOT_YET_RECRUITING | PHASE4

112 participants

A Comparison of Effectiveness, Safety, and Cost-effectiveness of Dapagliflozin and Empagliflozin in Patients With Type 2 Diabetes Mellitus and High Body Mass Index (BMI)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-24
Completion:: 2026-12-31

Conditions

Type 2 Diabetes

Interventions

DRUG

No Results Yet

NCT07311538 | NOT_YET_RECRUITING | PHASE2

56 participants

Phase IIa Study of BRY812 Monotherapy in Advanced Gynecological Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-31
Completion:: 2027-12-31

Conditions

Advanced Gynecological Malignancies

Interventions

DRUG

No Results Yet

NCT07311499 | NOT_YET_RECRUITING | NA

60 participants

Improvement of Sleep in COPD Patients Through Inhalation Management Education by Nurse.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2026-01-31
Completion:: 2026-12-31

Conditions

Chronic Obstructive Lung Disease

Interventions

BEHAVIORAL

No Results Yet

NCT07311486 | RECRUITING

1000 participants

Implementation of Biomarker-Based Care for mTBI - IMPACTS-BRAINI Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-07-15
Completion:: 2026-05-01

Conditions

Mild Traumatic Brain Injury (mTBI)

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07311473 | COMPLETED | NA

150 participants

Comprehensive Outcomes of Palatal TSADs Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-01-03
Completion:: 2025-09-10

Conditions

Malocclusions

Interventions

DEVICE

No Results Yet

NCT07311460 | COMPLETED | NA

28 participants

HIIT, Steroid Hormones and Mental Health in Adolescents

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-11-01
Completion:: 2025-01-25

Conditions

Hormone

Interventions

BEHAVIORAL

No Results Yet

NCT07311447 | COMPLETED

50 participants

Target-Controlled Infusion and Postoperative Neurocognitive Outcomes in Geriatric Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-05-05
Completion:: 2025-10-31

Conditions

Postoperative Cognitive Dysfunction (POCD)
Neurocognitive Function
Sedation and Analgesia
Geriatric Patients

No Results Yet

NCT07311421 | RECRUITING

49 participants

Raman Spectroscopy-Based Non-Invasive Blood Glucose Detection

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2026-01-01
Completion:: 2026-06-10

Conditions

Diabetes

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07311408 | RECRUITING | PHASE2

40 participants

SHR-1701 + Rivoceranib (± SHR-2554) in Advanced GC After First-Line Immunotherapy Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2026-01-01
Completion:: 2028-01-01

Conditions

Gastric Cancer (GC)
Gastroesophageal Junction Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT07308301 | NOT_YET_RECRUITING

95 participants

Examination of the Relationship Between Quality of Life and Caregiving Burden Among Caregivers of Pediatric Oncology Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2026-01-01
Completion:: 2026-03-31

Conditions

Childhood Cancer
Childhood Cancers
Caregiver Subjective Burden
Primary Caregivers of Children Newly Diagnosed With Cancer
Caregiver
Caregiver Anxiety
Caregiver Health Related QOL

Interventions

BEHAVIORAL

No Results Yet

NCT07307430 | NOT_YET_RECRUITING | NA

226 participants

Effect of Narrative Education on Glycemic Control in Adults With Type 2 Diabetes in Primary Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2026-02-15
Completion:: 2026-11-15

Conditions

Type 2 Diabetes Mellitus (T2DM)
Diabetes Self-management
Diabetes Education

Interventions

BEHAVIORAL

No Results Yet

NCT07307391 | COMPLETED | NA

6 participants

Exercise in Extreme Hot Weather Conditions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-07-07
Completion:: 2025-12-10

Conditions

Heat Acclimation and Thermotolerance
Heat Effect

Interventions

OTHER

No Results Yet

NCT07306858 | NOT_YET_RECRUITING

276 participants

CT-Based Deep Learning for Differentiating Acute and Chronic Osteoporotic Vertebral Compression Fractures

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-16
Completion:: 2025-12-29

Conditions

Osteoporotic Vertebral Compression Fractures

Interventions

OTHER

No Results Yet

NCT07306611 | COMPLETED | PHASE1/PHASE2

30 participants

Regenerative Treatment of Female Genital Atrophy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-06-04
Completion:: 2025-06-18

Conditions

Vulvo Vaginal Atrophy

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT07306000 | RECRUITING | NA

100 participants

Pilot Study: Effects of CCP Intervention on NICU Environment and Preterm Infants Development

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-22
Completion:: 2028-12-31

Conditions

Preterm Infant Development
Preterm Infant Health

Interventions

BEHAVIORAL

No Results Yet

NCT07305701 | RECRUITING

10000 participants

Cohort Study on Medical Students' Mental Health

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-10-22
Completion:: 2047-10-31

Conditions

Major Depressive Disorder
Generalized Anxiety Disorder
Suicidal Ideation
Alcoholism
Marijuana Abuse
Loneliness

Interventions

OTHER

No Results Yet

NCT07305506 | COMPLETED | NA

16 participants

Effects of Post-Match Foam Rolling, Static Stretching, and Passive Rest on Acute Cardiac-Autonomic, Hemodynamic, and Neuromuscular Recovery in National Wrestlers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-01-09
Completion:: 2024-02-25

Conditions

Cardiac Autonomic Function
Hemodynamic Changes
Neuromuscular Adaptations
Exercise and Recovery

Interventions

PROCEDURE

No Results Yet

NCT07304635 | COMPLETED | NA

42 participants

Comparison of the Postoperative Analgesic Effectiveness of Erector Spinae Plane Block Versus Its Combination With Superficial Parasternal Intercostal Plane Block Within the ERACS Program

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-08-30
Completion:: 2025-07-27

Conditions

Sternotomy
Postoperative Delirium
Postoperative Pain Management

Interventions

PROCEDURE

No Results Yet

NCT07304505 | RECRUITING | NA

50 participants

Probiotics in Adults With Rheumatoid Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-11-13
Completion:: 2026-03-31

Conditions

Rheumatoid Arthritis (RA)

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07303504 | NOT_YET_RECRUITING | NA

26 participants

Preparation for Sports Retirement: Study Protocol

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2026-02-01
Completion:: 2027-02-01

Conditions

Sport Retirement
Psychoeducation
Retirement
Adaptation
Psychosocial Factors
Psychology

Interventions

BEHAVIORAL

No Results Yet

NCT07303218 | ACTIVE_NOT_RECRUITING

100 participants

The HER Project: HRD in EGFR-mutated NSCLC

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-01
Completion:: 2029-12-31

Conditions

EGFR
Non Small Cell Lung Cancer
Homologous Recombination Deficiency
PARP Inhibitor

Interventions

OTHER

No Results Yet

NCT07303088 | COMPLETED | NA

52 participants

Effects of L-carnitine and Coenzyme Q10 Supplementation on Oxidative Stress in Tunisian Hemodialysis Patients.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-06-17
Completion:: 2024-11-30

Conditions

Oxidative Stress Response
Hemodialysis
End Stage Kidney Disease (ESRD)

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT07302191 | COMPLETED | NA

58 participants

High-Intensity Interval or Concurrent Exercise on Oxidative Stress and Inflammation in Obese Women

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-09-02
Completion:: 2025-11-20

Conditions

Women Veterans
Obese Women
Postmenopausal
Sedentary Lifestlye

Interventions

BEHAVIORAL

No Results Yet

NCT07301086 | NOT_YET_RECRUITING

2000 participants

Deep Learning-Assisted Ultrasonic Diagnosis and Localization of Testicular Appendix Torsion

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2026-01-31
Completion:: 2026-05-31

Conditions

Testicular Appendix Torsion
Testicular Torsion
Epididymitis

No Results Yet

NCT07300488 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

60 participants

Efficacy and Safety of Pracytarabine Versus Regorafenib in the Treatment of Patients With Hepatocellular Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-09-01
Completion:: 2027-02-28

Conditions

HCC

Interventions

DRUG

No Results Yet

NCT07300371 | COMPLETED | NA

96 participants

Intra-oral Evaluation of Force Decay of Pigmented and Transparent Elastomeric Power Chains:

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-11-19
Completion:: 2024-09-20

Conditions

Orthodontic Treatment
Malocclusion

Interventions

OTHER

No Results Yet

NCT07299110 | RECRUITING | NA

50 participants

Effect of Whey Protein Versus Egg Albumen Protein Challenge on Blood Ammonia Level in Patients of Decompensated Ethanol Related Cirrhosis.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-12
Completion:: 2025-12-31

Conditions

Decompensated Cirrhosis Ethanol Related

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07298499 | ENROLLING_BY_INVITATION | NA

100 participants

Amplification and Tinnitus Masker Performance and Benefit for Adults With Hearing Loss and Tinnitus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-07-07
Completion:: 2027-12-31

Conditions

Hearing Aid
Tinnitus

Interventions

DEVICE

No Results Yet

NCT07297368 | ACTIVE_NOT_RECRUITING | NA

30 participants

Enhanced Tai Chi for Parkinson's Disease (Enhanced Tai Chi PD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-05-01
Completion:: 2026-04-01

Conditions

Parkinson Disease (PD)

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT07297056 | COMPLETED | NA

40 participants

Mindfulness Psychoeducation for Bipolar Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-03-03
Completion:: 2025-05-02

Conditions

Bipolar Disorder (BD)
Mindfulness-Based Stress Reduction
Mindfulness Meditation

Interventions

OTHER

No Results Yet

NCT07295392 | NOT_YET_RECRUITING

30 participants

Is There Any Prognostic Value of Serum Uromodulin in Sepsis Induced AKI.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2026-03-10
Completion:: 2026-12-10

Conditions

Acute Kidney Injury

No Results Yet

NCT07292363 | COMPLETED

45 participants

Inflammation-Related Endothelial Barrier Dysfunction in Patients With Apical Periodontitis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2021-02-09
Completion:: 2022-04-30

Conditions

Apical Periodontitis
Healhty

Interventions

OTHER

No Results Yet

NCT07288008 | RECRUITING | NA

40 participants

Transcranial Alternating Current Stimulation (tACS) for the Treatment of Anxiety in Veterans: An Open-Label Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-15
Completion:: 2027-12-30

Conditions

Anxiety

Interventions

DEVICE

No Results Yet

NCT07287748 | RECRUITING | PHASE1

38 participants

A Phase I Trial of Af-001 in Patients With Differentiated Thyroid Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2026-01-01
Completion:: 2028-07-31

Conditions

DTC - Differentiated Thyroid Cancer

Interventions

DRUG

No Results Yet

NCT07286981 | COMPLETED | NA

40 participants

Glycemic Index of Date Cultivars and Date-based Products

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-08-16
Completion:: 2025-05-25

Conditions

Glycaemic Response Measurements

Interventions

OTHER

No Results Yet

NCT07286799 | COMPLETED

54 participants

Comparison of the Analgesic Efficacy of Transversalis Fascia Plane Block and Posterior Quadratus Lumborum Block in Pediatric Patient Undergoing Orchiopexy: A Prospective Observational Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-05-01
Completion:: 2025-11-01

Conditions

Pain Management
Orchiopexy
Transversalis Fascia Plane Block
Quadratus Lumborum Block

No Results Yet

NCT07283133 | COMPLETED | NA

34 participants

Effects of Task Specific Circuit Training on Gross Motor Function, Balance, and Quality of Life in Cerebral Palsy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-09-13
Completion:: 2025-12-10

Conditions

Cerebral Palsy (CP)
Quality of Life (QOL)

Interventions

PROCEDURE

No Results Yet

NCT07275229 | NOT_YET_RECRUITING | NA

62 participants

Efficacy and Safety of Irregular Pulsed Radiofrequency (Sluijter-Teixera Poisson) Versus Regular Pulsed Radiofrequency to the Gasserian Ganglion for Treatment of Primary Trigeminal Neuralgia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-31
Completion:: 2026-12-31

Conditions

Trigeminal Neuralgia

Interventions

PROCEDURE

No Results Yet

NCT07274995 | ACTIVE_NOT_RECRUITING

90 participants

Machine Learning-Based Prediction of Postoperative Pain After Pediatric Ambulatory Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-08-01
Completion:: 2026-11-30

Conditions

Pain, Acute Post-Operative
Ambulatory Surgical Procedures
Pediatric Pain
Pediatric Patient (1m-21y)

No Results Yet