Clinical Trials Updated in 2025

NCT07309887 | NOT_YET_RECRUITING

100000 participants

This Clinical Trial is a Retrospective, Multicenter Cohort Study Evaluating the Real-world Characteristics and Risk of Disease Recurrence in Hormone Receptor-positive, HER2-negative Early Breast Cancer.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-12-17
Completion:: 2026-01-31

Conditions

Early Breast Cancer

No Results Yet

NCT07309861 | COMPLETED | NA

119 participants

Effect Of Education On Adherence, Self Care And Well-Being Of Patients With Chronic Kidney Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2020-03-03
Completion:: 2021-10-29

Conditions

Chronic Kidney Disease (Stage 3-4)

Interventions

DEVICE

No Results Yet

NCT07309848 | RECRUITING

374 participants

Hip Fracture Surgery Timing and Blood Transfusion Risk in Patients on DOACs

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-11-01
Completion:: 2027-09-01

Conditions

Blood Transfusion
Hip Fracture Surgeries
Geriatric
Bleeding Complications
Bleeding as Surgical Complication (Treatment)
Bleeding
Blood Transfusions
Blood Transfusion Complication
Direct Oral Anticoagulants (DOACs)

No Results Yet

NCT07309835 | NOT_YET_RECRUITING

100 participants

Improving Genetic Medicine for Ethnic Minority Groups

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2026-01-30
Completion:: 2031-01-30

Conditions

Genetic Testing

No Results Yet

NCT07309822 | RECRUITING

27 participants

Study to Assess the Safety and Effectiveness of Beltaven® in Patients With Allergy to Apis Mellifera, Polistes Dominula or Vespula Spp.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-02-01
Completion:: 2031-05-31

Conditions

Allergy

No Results Yet

NCT07309770 | RECRUITING | PHASE2

90 participants

Trastuzumab Rezetecan in Advanced Solid Tumors Refractory to Standard Therapies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-12-18
Completion:: 2027-09-11

Conditions

Urachal Cancer
Advanced Solid Tumor Cancer
Antibody-drug Conjugates

Interventions

DRUG

No Results Yet

NCT07309744 | NOT_YET_RECRUITING | EARLY_PHASE1

30 participants

Universal CAR-T Cell Injection Targeting CD19/BCMA in Patients With Inflammatory Bowel Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-12-20
Completion:: 2027-12-30

Conditions

Moderate-to-severe Ulcerative Colitis
Crohn's Disease (CD)

Interventions

DRUG

No Results Yet

NCT07309718 | RECRUITING

400 participants

MPR for Stroke Risk Assessment of ICAS

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-12-01
Completion:: 2027-12-15

Conditions

ICAS - Intracranial Atherosclerosis
Stroke Ischemic
Hemodynamic

Interventions

DRUG

No Results Yet

NCT07309705 | ACTIVE_NOT_RECRUITING

400 participants

Digital Angiography-Derived Fractional Flow Assessment for Intracranial Stenosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-12-01
Completion:: 2027-01-01

Conditions

Intracranial Atherosclerosis ICAS
Hemodynamic
Stroke

Interventions

DRUG

No Results Yet

NCT07309692 | RECRUITING | NA

106 participants

Different Modalities for the Evaluation of Patients With Peri-menopausal Bleeding

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-12-01
Completion:: 2026-08-31

Conditions

Perimenopausal Bleeding

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07309640 | NOT_YET_RECRUITING | NA

38 participants

The Effects of Magnesium (Mg) Supplement and Alternate Maxillary Expansion and Constriction (Alt-RAMEC) in Patient With Transverse Maxillary Deficiency (TMD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2026-01-01
Completion:: 2026-08-12

Conditions

Magnesium During Orthodontic Expansion
Orthodontic Patients Indicated for Maxillary Expansion

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07309588 | ENROLLING_BY_INVITATION | PHASE1/PHASE2

100 participants

Hyaluronic Acid in the Treatment of Hyposalivation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-07-01
Completion:: 2025-12-19

Conditions

Xerostomia Due to Hyposecretion of Salivary Gland

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT07309575 | RECRUITING

102 participants

Regional Versus General Anesthesia for Hip Fracture and Postoperative Oxygenation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-11-27
Completion:: 2026-12-31

Conditions

Hip-fracture
General Anaesthesia
Regional Anaesthesia

No Results Yet

NCT07309497 | RECRUITING

208 participants

Pragmatic Geriatric Assessment Before CAR-T or Bispecific Antibody Therapy to Predict Side Effects and Outcomes in Older Patients (GA-ACT Trial)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-12-12
Completion:: 2027-12-01

Conditions

Multiple Myeloma (MM), Lymphoma, Large B-Cell, Diffuse (DLBCL), Lymphoma
CART Therapy
Bispecific Antibody
Geriatric Hematology

Interventions

OTHER

No Results Yet

NCT07309419 | NOT_YET_RECRUITING | PHASE2/PHASE3

222 participants

A Phase III Randomized Study of TACE Plus an Oral Triple-Agent Cocktail Versus TACE Plus First-Line Targeted Immunotherapy in Unresectable Hepatocellular Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-12-22
Completion:: 2030-06-30

Conditions

Hepatocellular Carcinoma

Interventions

DRUG
DEVICE

No Results Yet

NCT07309380 | NOT_YET_RECRUITING | PHASE3

150 participants

Phase III Clinical Trial of Hepalatide in Patients With Chronic Hepatitis D

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2026-04-30
Completion:: 2027-06-30

Conditions

Hepatitis D, Chronic

Interventions

DRUG

No Results Yet

NCT07309367 | RECRUITING | NA

100 participants

Web-based Advance Care Planning Intervention for Patients With Kidney Failure on Dialysis: Pilot Testing of 'My Voice'

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-10-02
Completion:: 2026-09-30

Conditions

Kidney Failure, Chronic Therapy; Hemodialysis

Interventions

OTHER

No Results Yet

NCT07309328 | NOT_YET_RECRUITING | PHASE2/PHASE3

220 participants

Evaluation of the Effectiveness of a Cardiac Coherence Exercise on MRI Success and Image Quality in Claustrophobic Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2026-01-31
Completion:: 2026-12-31

Conditions

Claustrophobia
MRI

Interventions

BEHAVIORAL

No Results Yet

NCT07309289 | RECRUITING | PHASE3

144 participants

NALIRIFOX Plus Targeted Therapy Versus FOLFOX Plus Targeted Therapy as First-line Treatment for Metastatic Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-07-01
Completion:: 2029-03-01

Conditions

Metastatic Colorectal Cancer (CRC)

Interventions

DRUG

No Results Yet

NCT07309263 | RECRUITING | NA

60 participants

Comparing the Effects of Smart App-Assited Super-Slow Jogging and Stationary Cycling on Respiratory Function and Aerobic Fitness in College Students

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-11-20
Completion:: 2026-01-31

Conditions

Sedentary Lifestlye
Young Adult

Interventions

BEHAVIORAL

No Results Yet

NCT07309250 | NOT_YET_RECRUITING

932 participants

A Study on Gastrointestinal Transit Time at the Population Level

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-12-31
Completion:: 2026-12-30

Conditions

Gastrointestinal Transit Time

Interventions

OTHER

No Results Yet

NCT07309237 | COMPLETED | NA

30 participants

Spinning-Based High-Intensity Interval Training Induces Greater Cardiopulmonary Adaptations Than Continuous Training in Sedentary College Men

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2024-08-01
Completion:: 2025-01-30

Conditions

Sedentary Lifestlye
Male

Interventions

BEHAVIORAL

No Results Yet

NCT07309211 | RECRUITING

25 participants

Durvalumab as Consolidation Therapy in Patients With LS-SCLC Following sCRT

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-07-08
Completion:: 2025-12-31

Conditions

SCLC, Limited Stage

No Results Yet

NCT07309185 | RECRUITING | PHASE2

66 participants

Adebrelimab Combined With Famitinib and Irinotecan in Advanced Gastric Cancer After Failure of First-Line Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2024-07-24
Completion:: 2027-07-31

Conditions

Stomach Neoplasms

Interventions

DRUG

No Results Yet

NCT07309172 | RECRUITING

34 participants

KetoBrain: Brain Energy Metabolism in Schizophrenia

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-04-15
Completion:: 2027-12-15

Conditions

Schizophrenia Disorder

No Results Yet

NCT07309133 | RECRUITING

25 participants

Local Field Potentials in Dystonia

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-09-04
Completion:: 2028-12-31

Conditions

Dystonia
Dystonia, Focal
Dystonia, Primary

Interventions

DEVICE

No Results Yet

NCT07309094 | RECRUITING

250 participants

Clinical, Morphometric and Biochemical Effects on Adiposopathy Associated With the Use of GLP-1RA in CKD

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2023-09-15
Completion:: 2027-07-31

Conditions

Chronic Kidney Disease stage3
Chronic Kidney Disease stage4
Chronic Kidney Disease Stage 1
Chronic Kidney Disease Stage 2
Obesity
Diabetes Mellitus, Type 2

Interventions

DRUG

No Results Yet

NCT07309081 | NOT_YET_RECRUITING | NA

40 participants

Effect of Soleus Muscle Kinetic Control Training on Gait and Electromyographic Activity in Patients With Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-12-15
Completion:: 2026-06-15

Conditions

Stroke

Interventions

OTHER

No Results Yet

NCT07309042 | NOT_YET_RECRUITING | PHASE1

24 participants

Phase 1 Study of the Safety and Pharmacokinetics of YN001 With Rosuvastatin in Healthy Chinese Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-12-31
Completion:: 2026-02-28

Conditions

Atherosclerotic Cardiovascular Diseases
Cerebrovascular Diseases

Interventions

DRUG

No Results Yet

NCT07309029 | RECRUITING

30 participants

Pre-Emptive LAVA-ECMO for Complex High-Risk TAVR

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2026-01-01
Completion:: 2027-05-30

Conditions

Severe Aortic Stenosis
Cardiogenic Shock
Cardiogenic Shock, ECMO
Trans-catheter Aortic Valve Implantation

Interventions

DEVICE

No Results Yet

NCT07309016 | NOT_YET_RECRUITING | NA

50 participants

Weighted Blanket in Pregnancy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-12-30
Completion:: 2026-07-15

Conditions

Leg Cramps, Nocturnal
Poor Sleep Quality
Pregnancy
Anxiety
Stress

Interventions

DEVICE

No Results Yet

NCT07309003 | RECRUITING

52 participants

The Effects of Functional Electrical Stimulation (FES) and Exercise on the Quadriceps in Patients With Knee Osteoarthritis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-01-03
Completion:: 2025-12-30

Conditions

Osteoarthritis (OA) of the Knee

Interventions

DEVICE

No Results Yet

NCT07308990 | RECRUITING | NA

800 participants

Limited Versus Extended Lymph Node Dissection During Radical Prostatectomy in Patients With Localized or Locally Advanced Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-10-29
Completion:: 2030-05-30

Conditions

Prostate Cancer Patients Undergoing Radical Prostatectomy

Interventions

PROCEDURE

No Results Yet

NCT07308964 | NOT_YET_RECRUITING | PHASE4

40 participants

Comparison of the Efficacy and Safety of 4 vs. 8 Treatments With Tepezza (Teprotumumab) for Thyroid Eye Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2026-01-31
Completion:: 2028-01-31

Conditions

Thyroid Eye Disease
Thyroid Eye Disease, TED
Thyroid Eye Disease (TED)

Interventions

DRUG

No Results Yet

NCT07308951 | RECRUITING | NA

290 participants

Effect of Patient-Controlled Transcutaneous Electrical Acupoint Stimulation on Quality of Life in Chronic Cancer Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-09-10
Completion:: 2026-10-31

Conditions

Quality of Life
Chronic Cancer Pain

Interventions

OTHER

No Results Yet

NCT07308925 | NOT_YET_RECRUITING | NA

108 participants

Real-time Continuous Glucose Monitoring Compared With Intermittent Continuous Glucose Monitoring in People With Type 2 Diabetes Treated With Insulin.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2026-01-31
Completion:: 2028-05-31

Conditions

Type 2 Diabetes

Interventions

DEVICE

No Results Yet

NCT07308912 | COMPLETED | NA

36 participants

Effect of GaAlAs 940 Laser on Pain and Wound Healing After Free Gingival Graft

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2024-10-01
Completion:: 2025-10-01

Conditions

Low Level Laser Therapy
Healthy
Postoperative Pain Management
Wound Healing

Interventions

DEVICE

No Results Yet

NCT07308899 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:: 2025-12-30

No Results Yet

NCT07308860 | ACTIVE_NOT_RECRUITING

1500 participants

Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (FAME) 3 Extended

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-08-01
Completion:: 2030-06-30

Conditions

Coronary Artery Disease

Interventions

PROCEDURE

No Results Yet

NCT07308821 | NOT_YET_RECRUITING | NA

65 participants

Effects of a Peer-mentoring Program on Undergraduate Students' Outcomes and Perspectives Related to a Career in Communication Sciences and Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-12-15
Completion:: 2026-06-30

Conditions

Mentoring

Interventions

BEHAVIORAL

No Results Yet