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MPR for Stroke Risk Assessment of ICAS

NCT07309718 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 400

Last updated 2025-12-30

No results posted yet for this study

Summary

Intracranial atherosclerotic stenosis (ICAS) carries substantial stroke risk despite optimal medical treatment. Current risk stratification relies primarily on stenosis severity, but novel hemodynamic markers may improve prediction. In this multiple prospective registry study we aim to investigate whether regional hemodynamics, measured by a novel Magnetic resonance imaging-derived Pressure Ratio (MPR) technique, are associated with stroke risk in ICAS.

Conditions

  • ICAS - Intracranial Atherosclerosis
  • Stroke Ischemic
  • Hemodynamic

Interventions

DRUG

Standardized medical therapy targeting vascular risk factors and stroke prevention

Dual antiplatelet treatment and management of vascular risk factors, in accordance with AHA/ASA guidelines

Sponsors & Collaborators

  • Xuanwu Hebei Hospital

    collaborator UNKNOWN

  • Xuanwu Xiongan Hospital

    collaborator UNKNOWN

  • Xuanwu Chifeng Hospital

    collaborator UNKNOWN

  • Xuanwu Jinan Hospital

    collaborator UNKNOWN

  • Xuanwu Hospital, Beijing

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-12-01
Primary Completion
2027-12-15
Completion
2028-03-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07309718 on ClinicalTrials.gov