Hip Fracture Surgery Timing and Blood Transfusion Risk in Patients on DOACs
NCT07309848 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 374
Last updated 2025-12-30
Summary
This study looks at patients with hip fractures who are taking direct oral anticoagulants (DOACs), a type of blood thinner. In many hospitals, surgery for these patients is delayed because of concerns about bleeding, but waiting longer can also increase risks such as complications and longer hospital stays. The purpose of this study is to find out whether operating within 24 hours is as safe as delaying surgery beyond 24 hours. Specifically, the investigators want to know if early surgery does not lead to a higher need for blood transfusions compared to delayed surgery.
Conditions
- Blood Transfusion
- Hip Fracture Surgeries
- Geriatric
- Bleeding Complications
- Bleeding as Surgical Complication (Treatment)
- Bleeding
- Blood Transfusions
- Blood Transfusion Complication
- Direct Oral Anticoagulants (DOACs)
Sponsors & Collaborators
-
St. Antonius Hospital
lead OTHER
Principal Investigators
-
Henk Jan Schuijt, MD, PhD · Amsterdam University Medical Center
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-11-01
- Primary Completion
- 2027-09-01
- Completion
- 2027-12-31
Countries
- Netherlands
Study Locations
More Related Trials
-
Evaluation of TXA Prior to Surgery in the Geriatric Hip Fracture Population
NCT03923959 ·Status: COMPLETED ·Phase: PHASE3
-
Does Early Administration of Tranexamic Acid Reduce Blood Loss and Perioperative Transfusion Requirement
NCT03182751 ·Status: COMPLETED ·Phase: PHASE2
-
Single Dose of Tranexamic Acid and Blood Loss, in Elderly Patients With Hip Fracture
NCT03251469 ·Status: UNKNOWN ·Phase: PHASE2
-
Postoperative Blood Transfusion for Frail Elderly With Hip Fracture
NCT01102010 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Noninferiority Oral Tranexamic Acid vs Intravenous Administration in Total Hip Arthroplasty
NCT04691362 ·Status: COMPLETED ·Phase: PHASE4
-
Preoperative Versus Postoperative Start With Thromboprophylaxis in THA (Total Hip Arthroplasty)
NCT01714297 ·Status: COMPLETED ·Phase: PHASE4
-
Heart and Renal Failure in Hip Fracture Surgery
NCT03532919 ·Status: COMPLETED
-
Study Comparing Topical Versus Intravenous Tranexamic Acid in Anterior Total Hip Arthroplasty
NCT03359525 ·Status: UNKNOWN ·Phase: PHASE4
-
Effect of Early Administration of TXA in Adult Hip Fractures
NCT05047133 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
The Effect of Topical Application of Tranexamic Acid in Total Hip Arthroplasty Through the Direct Anterior Approach
NCT01622946 ·Status: COMPLETED ·Phase: PHASE4
-
Tranexamic Acid in HIp Fracture Surgery (THIF Study)
NCT00327106 ·Status: COMPLETED ·Phase: PHASE3
-
Transfusion Rates in Total Hip Replacement Before/After the Implementation of a Patient Blood Management Program.
NCT04398238 ·Status: COMPLETED
-
Prevention of Postoperative Bleeding in Subcapital Femoral Fractures
NCT02150720 ·Status: COMPLETED ·Phase: PHASE3
-
The Effect of Administration of Low Dose Adrenaline During Surgery on Bleeding During Hip Surgery
NCT01708642 ·Status: COMPLETED ·Phase: PHASE3
-
Study of the Effect of Tranexamic Acid Administered to Patients With Hip Fractures. Can Blood Loss be Reduced?
NCT01535781 ·Status: TERMINATED ·Phase: NA
-
Prospective Study: TXA, Anticoagulant, Orthopaedic Trauma
NCT07116395 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Topical Tranexamic Acid and Acute Blood Loss in Total Hip Arthroplasty
NCT01683955 ·Status: COMPLETED ·Phase: PHASE1
-
Tranexamic Acid in Total Hip Arthroplasty.
NCT02252497 ·Status: COMPLETED ·Phase: PHASE4
-
A New Approach to a Personalized Patient Blood Management Program (pPBM) in Total Hip Arthroplasty (THA)
NCT02519088 ·Status: COMPLETED
-
Tranexamic Acid Use and Blood Loss in Total Hip Arthroplasty
NCT02989155 ·Status: COMPLETED
-
Can Thrombelastography Predict Blood Loss in Patients With Hip Fractures
NCT02297061 ·Status: COMPLETED
-
Clinical Trial to Assess the Efficacy of Tranexamic Acid in Reducing Blood Loss in Hip Fracture Patients.
NCT05489185 ·Status: UNKNOWN ·Phase: PHASE4
-
This is a Study to Verify if Tranexamic Acid Can Reduce the Anemia After a Femoral Shaft Fractures Surgery
NCT04803591 ·Status: WITHDRAWN ·Phase: PHASE4
-
Effect of Intravenous Tranexamic Acid on Reduction of Blood Losses in Hip Fracture Patients
NCT03211286 ·Status: COMPLETED ·Phase: PHASE4
-
Tranexamic Acid Use in Acute Hip Fractures
NCT02947529 ·Status: COMPLETED ·Phase: PHASE4