Clinical Trials Updated in 2025

NCT06966258 | RECRUITING | NA

90 participants

Inspire HER: Inspiring the Heart and Emotions for Radical Health

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-11-15
Completion:: 2029-01-31

Conditions

Cardiovascular-kidney-metabolic Syndrome
Cardiovascular Diseases
Hypertension
Diabetes
Hyperlipidemia
Kidney Disease
Obesity
Smoking

Interventions

BEHAVIORAL

No Results Yet

NCT06948578 | COMPLETED | NA

34 participants

Thread-Embedding Acupuncture for Functional and QoL Improvement in COPD Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-07-01
Completion:: 2025-11-30

Conditions

Chronic Pulmonary Obstruction

Interventions

DEVICE

No Results Yet

NCT06921473 | COMPLETED | PHASE4

102 participants

Effect of Ephedrine vs. Norepinephrine on Prevention of Fetal Acidosis During Cesarean Section Under Spinal Anesthesia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-09-01
Completion:: 2025-12-12

Conditions

Cesarean Delivery Affecting Newborn
Acidosis
Maternal Hypotension
Spinal Aneshtesia

Interventions

DRUG

No Results Yet

NCT06899230 | ACTIVE_NOT_RECRUITING | PHASE1

72 participants

Safety, Tolerability, and Pharmacokinetics (PK) of Single and Multiple Ascending Oral Doses of iQ-007

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-04-08
Completion:: 2026-01-29

Conditions

Drug Resistant Epilepsy
Focal Seizure

Interventions

DRUG

No Results Yet

NCT06882135 | RECRUITING | PHASE1

76 participants

HW071021 Monotherapy in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-05-28
Completion:: 2026-09-30

Conditions

Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT06881823 | WITHDRAWN | PHASE1/PHASE2

0 participants

Study to Assess [177Lu]Lu-PSMA-R2 (AAA602) and [225Ac]Ac-PSMA-R2 (AAA802) in Participants With PSMA-positive HRLPC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2026-06-29
Completion:: 2030-03-31

Conditions

Prostate Cancer

Interventions

DRUG

No Results Yet

NCT06874894 | ENROLLING_BY_INVITATION

1021 participants

Thromboembolic And Bleeding Risks During anticoaGulant trEatment in Asian paTients With Atrial Fibrillation (TARGET-AF)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-05-25
Completion:: 2026-08-30

Conditions

Fibrillation, Atrial

No Results Yet

NCT06844630 | COMPLETED | NA

60 participants

Interscalene vs Infraspinatus-teres Minor (ITM) Interfascial Block in Shoulder Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-03-01
Completion:: 2025-06-30

Conditions

Shoulder Pain
Pain, Postoperative
Surgical Procedure, Unspecified

Interventions

OTHER

No Results Yet

NCT06834100 | RECRUITING | PHASE3

240 participants

Assessment of Immunogenicity, Reactogenicity and Safety of the Drug GNG-DE in Comparison With the Reference Drug

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-02-12
Completion:: 2025-12-31

Conditions

Infections
Meningococcal

Interventions

DRUG

No Results Yet

NCT06820099 | RECRUITING | PHASE2

225 participants

Study on the Efficacy and Safety of HRS-7535 in Patients With Mild Decrease in Ejection Fraction/Preserved Ejection Fraction Heart Failure and Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-04-10
Completion:: 2026-12-31

Conditions

Adults With Heart Failure, Mild Decrease in Ejection Fraction/Preserved Ejection Fraction, and Obesity

Interventions

DRUG

No Results Yet

NCT06811285 | COMPLETED | NA

97 participants

Kinesio Taping and Foot Massage for Post-Cesarean Recovery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-12-02
Completion:: 2025-04-18

Conditions

Pain
Fatigue
Mood (Psychological Function)
Postpartum Women

Interventions

OTHER

No Results Yet

NCT06796894 | RECRUITING

60 participants

Symptoms, Respiratory Dysfunction and Frailty Level in Allergic and Eosonophilic Asthmatics

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-08-01
Completion:: 2026-10-30

Conditions

Asthma
Respiratory Disease
Fragility

No Results Yet

NCT06793670 | RECRUITING | PHASE4

1500 participants

Landiolol in Mitral Valve Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-01-28
Completion:: 2027-06-30

Conditions

Cardiac Failure
Low Cardiac Output Syndrome

Interventions

DRUG

No Results Yet

NCT06753877 | COMPLETED | NA

200 participants

Clinical Monitoring Using ICF

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-06-01
Completion:: 2024-10-01

Conditions

Stroke

Interventions

BEHAVIORAL

No Results Yet

NCT06735430 | COMPLETED | NA

86 participants

Ciprofol Based on Total Intravenous Anesthesia During Pediatric Laparoscopic Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-03-09
Completion:: 2025-08-31

Conditions

Pediatric Hernia
Laparoscopic Surgery
Appendicitis, Surgery

Interventions

DRUG

No Results Yet

NCT06700902 | RECRUITING | NA

300 participants

Taking Action for College Students

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-09-01
Completion:: 2027-05-31

Conditions

Major Depressive Disorder
Bipolar Disorder
Schizophrenia

Interventions

BEHAVIORAL

No Results Yet

NCT06667518 | COMPLETED

20 participants

Knee Neuromuscular Assessment in Children With Cerebral Palsy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-09-20
Completion:: 2025-01-01

Conditions

Force Measurement
Electromyography
Children
Cerebral Palsy
Lower Limb

Interventions

DEVICE

No Results Yet

NCT06667492 | RECRUITING

30 participants

Lower Extremity Dynamometry Assessment in Neurotypical Children

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-09-20
Completion:: 2026-06-30

Conditions

Force Measurement
Children
Lower Limb
Assessment Tool

Interventions

DEVICE

No Results Yet

NCT06648915 | ACTIVE_NOT_RECRUITING

364 participants

Lipoprotein(a) and Progression of Aortic Stenosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-02-10
Completion:: 2026-02-28

Conditions

Aortic Valve Stenosis
Lipoprotein(a)

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06645808 | RECRUITING | EARLY_PHASE1

32 participants

PET-imaging of Two Vartumabs in Patients With Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-12-10
Completion:: 2026-08-31

Conditions

Solid Tumor
Colon Carcinoma
Rectal Carcinoma
Osteosarcoma
Chondrosarcoma
Lung Carcinoma
Head and Neck Squamous Cell Carcinoma
Esophageal Carcinoma
Gastric Carcinoma
Pancreas Carcinoma
Bladder Carcinoma
Glioblastoma
Soft Tissue Sarcoma (STS)
Breast Cancer

Interventions

BIOLOGICAL
RADIATION

No Results Yet

NCT06640894 | RECRUITING | NA

66 participants

Power2Walk: The Impact of Functional Power Training on Participation and Activity in Children With Cerebral Palsy.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-07-19
Completion:: 2027-08-31

Conditions

Cerebral Palsy, Spastic

Interventions

OTHER

No Results Yet

NCT06629649 | RECRUITING | NA

1800 participants

Implementing AI-based Glaucoma Screening Within Federally Qualified Health Centers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-10-22
Completion:: 2029-09-29

Conditions

Glaucoma
Ocular Hypertension

Interventions

OTHER

No Results Yet

NCT06626659 | COMPLETED

40 participants

Lipoprotein (a) and Vascular Regenerative Cell Content

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-10-05
Completion:: 2024-12-03

Conditions

Cardiovascular Diseases
Atherosclerosis Cardiovascular Disease
Ischemic Heart Disease
Dyslipidemia

No Results Yet

NCT06625541 | COMPLETED | PHASE1

57 participants

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AJ302-IM in Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-06-24
Completion:: 2025-08-15

Conditions

Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT06614270 | RECRUITING | NA

15 participants

Anti-CD19 IL-10/IL15 CAR-NK Cells in Refractory/Relapsed Autoimmune Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-01-06
Completion:: 2026-01-06

Conditions

Systemic Sclerosis (SSc)
ANCA Associated Vasculitis (AAV)
Idiopathic Inflammatory Myopathy (IIM)
Sjogren's Syndrome
Antiphospholipid Syndrome
Systemic Lupus Erythematosus

Interventions

DRUG

No Results Yet

NCT06603181 | COMPLETED | NA

60 participants

Effect of Extracorporeal Shock Wave Therapy (ESWT) and Phonophoresis Treatment in Patients With Lateral Epicondylitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-09-25
Completion:: 2025-01-30

Conditions

Lateral Epicondylitis
Extracorporeal Shock Wave Therapy
Phonophoresis

Interventions

OTHER

No Results Yet

NCT06602037 | RECRUITING | NA

90 participants

ImmunoPET Imaging of Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-11-20
Completion:: 2027-06-30

Conditions

Neoplasms Pancreatic

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06588205 | RECRUITING

200 participants

Exploring the Clinical Impact of MYC Aberrations and Their Relationship With Microenvironment in Diffuse Large B Cell Lymphoma and High-Grade B Cell Lymphoma

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-05-05
Completion:: 2027-12-31

Conditions

Diffuse Large B Cell Lymphoma
High-grade B-cell Lymphoma
High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements

No Results Yet

NCT06587386 | COMPLETED | PHASE4

55 participants

The Minimum Effective Dose (ED90) of Liposomal Bupivacaine for Preserving Motor Function

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-05-20
Completion:: 2025-11-10

Conditions

Motion Sickness

Interventions

DRUG

No Results Yet

NCT06581627 | COMPLETED | PHASE1

24 participants

A Research Study Looking at a Single Dose of Etavopivat in Healthy Chinese Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-08-26
Completion:: 2024-10-31

Conditions

Healthy Volunteers
Sickle Cell Disease
Thalassemia

Interventions

DRUG

No Results Yet

NCT06562673 | COMPLETED | PHASE1/PHASE2

10 participants

Intra-arterial Cisplatin Plus Rh-endostatin Combined With Systematic Chemotherapy in Osteosarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-12-03
Completion:: 2025-04-17

Conditions

Osteosarcoma
Bone Cancer

Interventions

DRUG

No Results Yet

NCT06559371 | RECRUITING

150 participants

68Ga FAPI PET/CT Evaluation of Axillary Lymph Node Status After Neoadjuvant Therapy in Patients With Clinical Axillary Lymph Node Positive Breast Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-08-30
Completion:: 2026-06-30

Conditions

BREAST CANCER
PET/CT

No Results Yet

NCT06549699 | COMPLETED | NA

206 participants

Medically Used Tailored Traditional Food to Optimize Nutrition in Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-05-12
Completion:: 2025-11-11

Conditions

Heart Failure

Interventions

OTHER

No Results Yet

NCT06535659 | RECRUITING

122 participants

VitaFlow LIBERTY Europe

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-05-06
Completion:: 2027-06-06

Conditions

Aortic Valve Stenosis

Interventions

DEVICE

No Results Yet

NCT06534723 | RECRUITING | PHASE3

570 participants

Phase 3 Clinical Trial of Wujia Yizhi Granules in the Treatment of Mild-to-moderate Alzheimer's Dementia (Syndrome of Deficiency of Spleen and Kidney)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-08-20
Completion:: 2026-08-31

Conditions

Alzheimer's Dementia

Interventions

DRUG

No Results Yet

NCT06525532 | RECRUITING

35 participants

Clinical-MRI Evaluation in Patients Undergoing Subtalar Arthrorisis With Reabsorbable Endorthesis Implant in PLLA

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-06-12
Completion:: 2026-11-30

Conditions

Lower Limb Deformity

Interventions

OTHER

No Results Yet

NCT06522932 | RECRUITING | PHASE1

32 participants

PET Imaging Study of 64Cu-GRIP B for Patients Receiving CD19-directed CAR-T Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-10-23
Completion:: 2027-01-31

Conditions

Non Hodgkin Lymphoma

Interventions

DRUG
PROCEDURE

No Results Yet

NCT06510998 | RECRUITING | NA

390 participants

Isometric Resistance Exercise for Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-01-01
Completion:: 2027-07-28

Conditions

Hypertension

Interventions

BEHAVIORAL

No Results Yet

NCT06494189 | COMPLETED | PHASE1

9 participants

Low-dose Radiotherapy Plus Tislelizumab in Combination With Afatinib for Neoadjuvant Treatment of Surgically Resectable Head and Neck Squamous Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-07-31
Completion:: 2025-04-10

Conditions

Head and Neck Cancer

Interventions

BIOLOGICAL
DRUG
RADIATION

No Results Yet

NCT06492434 | COMPLETED | NA

16 participants

Enhancing Community Participation Through Peer-Delivered Decision Support

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-07-01
Completion:: 2025-08-31

Conditions

Severe Mental Disorder

Interventions

BEHAVIORAL

No Results Yet